Chapter 1: Introduction to Pathology
Test Bank
MULTIPLE CHOICE
- The sequence of events producing cellular changes following injury best defines:
a. manifestations.
b. pathogenesis.
c. sign.
d. symptom.
ANS: B REF: p. 2 - An abnormal disturbance of the function and structure of the human body following injury
refers to:
a. disease.
b. etiology.
c. manifestations.
d. pathogenesis.
ANS: A REF: p. 2 - The study of the cause of disease is termed:
a. disease.
b. etiology.
c. pathogenesis.
d. prognosis.
ANS: B REF: p. 2 - Common agents that cause disease include:
- bacteria.
- chemicals.
- heat.
a. 1 and 2 only
b. 1 and 3 only
c. 2 and 3 only
d. 1, 2, and 3
ANS: D REF: p. 2 - A syndrome is best defined as:
a. a genetic abnormality of a single protein.
b. an adverse response to medical treatment.
c. the patient’s perception of the disease.
d. signs and symptoms that characterize a specific abnormal disturbance.
ANS: D REF: p. 2 - An adverse response to medical treatment itself is termed:
a. autoimmune.
b. iatrogenic.
c. idiopathic.
d. nosocomial.
ANS: B REF: p. 3
- Prognosis refers to:
a. diseases usually having a quick onset.
b. the name of the particular disease.
c. the predicted course and outcome of the disease.
d. the structure of cells or tissue.
ANS: C REF: p. 3 - Diseases that generally require a decrease in the exposure technique are considered:
a. destructive.
b. lytic.
c. subtractive.
d. all of the above.
ANS: D REF: p. 3 - The investigation of disease occurring in large groups best defines:
a. epidemiology.
b. incidence.
c. prevalence.
d. all of the above.
ANS: A REF: p. 3 - Data regarding the number of deaths caused by a particular disease averaged over a population
are collected and reported by the:
a. American College of Radiology.
b. Centers for Disease Control.
c. Food and Drug Administration.
d. National Center for Health Statistics.
ANS: D REF: p. 2 - Which of the following are leading causes of death in the United States for adults aged 45
years and greater? - Heart disease
- Malignant neoplasm
- Polycystic kidney disease
a. 1 and 2 only
b. 1 and 3 only
c. 2 and 3 only
d. 1, 2, and 3
ANS: A REF: p. 4 - In 2010, health spending accounted for approximately _% of the U.S. gross domestic
product.
a. 12
b. 17
c. 21
d. 33
ANS: B REF: p. 7
- Each cell in the human body, except the reproductive cells, contains _ pairs of autosomal chromosomes and _ sex chromosomes.
a. 11; 1
b. 11; 2
c. 22; 1
d. 22; 2
ANS: D REF: p. 8 - The types of gene maps that grew out of the identification of DNA sequences include _
maps. - genetic
- SNP
- physical
a. 1 and 2 only
b. 1 and 3 only
c. 2 and 3 only
d. 1, 2, and 3
ANS: B REF: p. 8 - The identification of common DNA pattern sequences and common patterns of genetic
variations of single DNA bases resulted in:
a. the Genome Project.
b. genetic linkage maps.
c. haplotype mapping.
d. physical mapping.
ANS: C REF: p. 8 - Diseases that are present at birth from genetic or environmental factors are classified as:
a. congenital.
b. degenerative.
c. genetic.
d. metabolic.
ANS: A REF: p. 10 - A genetic disorder caused by an abnormality on one of the 22 nonsex chromosomes is
considered:
a. autosomal.
b. dominant.
c. recessive.
d. sex linked.
ANS: A REF: p. 11
- A protein coat surrounding a genome of either RNA or DNA without an organized cellular
structure best describes which type of microorganism?
a. Bacteria
b. Fungi
c. Virus
d. All of the above
ANS: C REF: p. 11 - The ease with which a pathogenic organism can overcome the body’s defenses best describes:
a. etiology.
b. infection.
c. pathogenesis.
d. virulence.
ANS: D REF: p. 12 - Diseases caused by the disturbance of normal physiologic function are classified as:
a. degenerative.
b. metabolic.
c. neoplastic.
d. traumatic.
ANS: B REF: p. 13 - The lymph node into which the primary neoplasm drains during metastasis is termed the
_ node.
a. primary
b. sentinel
c. metastatic
d. neoplastic
ANS: B REF: p. 14 - The spread of cancerous cells into surrounding tissue by virtue of the close proximity best
describes:
a. lymphatic spread.
b. hematogenous spread.
c. invasion.
d. oncogenesis.
ANS: C REF: p. 16 - Cancer originating in epithelial tissue is termed:
a. carcinoma.
b. leukemia.
c. lymphoma.
d. sarcoma.
ANS: A REF: p. 16