MLS Hematology Exam Questions and Answers (Verified
Answers) 2023
What is the first type of cell produced by the developing embryo? – correct
answers ✅Erythrocyte
What percentage of tissue located in the bone marrow cavities of adults is
fat? – correct answers ✅50%
Which of the following is not characteristic of pluripotent hematopoietic
stem cells? – correct answers ✅Express the stem marker CD13
In an adult, what are the two best areas for obtaining active bone marrow by
aspiration? – correct answers ✅Posterior iliac crest, sternum
What is the normal ratio of myeloid to erythroid precursors in bone marrow
(M:E ratio)? – correct answers ✅4:1
Which of the following does not accurately describe hematopoietic growth
factors? – correct answers ✅Action of majority is lineage restricted
In the third month of gestation, what is the primary site of hematopoiesis? –
correct answers ✅Liver
The mechanism that relays information about tissue oxygen levels to
erythropoietin-producing sites is located in the: – correct answers ✅Kidney
MLS Hematology Exam Questions and Answers (Verified
Answers) 2023
Antigen-independent lymphopoiesis occurs in primary lymphoid tissue
located in the: – correct answers ✅Thymus and bone marrow
Programmed cell death is called: – correct answers ✅Apoptosis
In what area of the bone marrow does hematopoiesis take place? – correct
answers ✅Cords
Bone marrow cellularity refers to the ration of: – correct answers
✅Hematopoietic tissue to adipose tissue
Interleukins and colony stimulating factors are cytokines produced by: –
correct answers ✅Monocytes and T lymphocytes
What is the approximate total blood volume in an adult? – correct answers
✅6 L
The myeloid progenitor cell can produce cells committed to: – correct
answers ✅Granulocytic, erythrocytic, monocytic, or megakaryocytic
lineages
The largest hematopoietic cells in normal bone marrow are: – correct
answers ✅Megakaryocytes
MLS Hematology Exam Questions and Answers (Verified
Answers) 2023
When evaluating a bone marrow aspirate smear, which finding is considered
abnormal? – correct answers ✅The presence of 10% myeloblasts on the cell
differential count
As most blood cell lines mature, which of the following is characteristic? –
correct answers ✅Nucleus to cytoplasm ratio (N:C) decreases
Which of the following describes thrombopoietin (TPO)? – correct answers
✅Hormone produced by the liver that stimulates megakaryopoiesis
When the hepatic phase of fetal life is reactivated in an adult, hematopoiesis
can be termed: – correct answers ✅Myeloid metaplasia or extramedullary
What is the average life span of a normal red blood cell? – correct answers
✅120 days
The Na+-K+ cation pump is an important mechanism in keeping the red
blood cell intact. Its function is to maintain a high level of: – correct answers
✅Intracellular K+
Which of the following depicts the structure of the hemoglobin molecule? –
correct answers ✅Four heme groups, four globin chains
Which of the following describes the process known as culling? – correct
answers ✅Removal of abnormal red cells by spleen
MLS Hematology Exam Questions and Answers (Verified
Answers) 2023
Hemoglobin forms that are incapable of oxygen transport include: – correct
answers ✅Carboxyhemoglobin and methemoglobin
The majority of iron found in an adult is a constituent of: – correct answers
✅Hemoglobin
A senescent red blood cell is one that has: – correct answers ✅Lived its life
span
What red cell morphologic abnormality is described by the term
“poikilocytosis”? – correct answers ✅Deviations from normal shape
Howell-Jolly bodies are composed of: – correct answers ✅DNA
When spherocytes are reported, what is observed on the peripheral blood
smear? – correct answers ✅Red cells without a central pallor
The red cells found in lead poisoning characteristically exhibit coarse
granules composed of _ that are reported as . – correct
answers ✅Aggregated ribosomes; basophilic stippling
Rouleaux of red blood cells when seen in the monolayer of a blood smear is
characteristic of: – correct answers ✅Multiple myeloma