NURS 251 Pharmacology Final Exam-Portage Learning

Sublingual: When rapid effect is needed right away
Subcutaneous: Destroy or inactivated in the GI Tract
Intramuscular: Used for drugs with poor oral absorption
Topical: For local effects on skin and eyes
Pharmaceutics is the study of how various dosage forms influence the way in
which the drug affects the body/ Administration of dosage form, dissolution of
drug into body/ manipulating chemical compound.
Pharmacokinetics is the study of what the body does to the drug, including
absorption, distribution, metabolism, and excretion/ Absorption, distribution,
metabolism, excretion.
Pharmacodynamics is the study of what the drug does to the body/ Drugreceptor interaction.

  1. The drug naltrexone is given to prevent relapse or cravings in individuals who
    use opioids. It binds to opioid receptors blocking endogenous agonist and other
    opioid drugs from binding and having an effect. Naltrexone is a/an
    Competitive agonist (binds to the same site of agonist)
  2. Due to the many chronic diseases associated with aging the elderly can have
    decreased blood flow to the liver. With age, there can also be a decrease in liver
    enzymes, which can increase the duration of a drug in the patient’s systems.
    Which pharmacokinetic process is affected in this scenario?
    Metabolism (stored in the body)/ cytochrome P-450 enzymes/ liver/ Grapefruit
    and statins
  3. When the combined effect of two drugs is greater than the sum of the
    individual effects it refers to
    Synergism: When the combined effect of two drugs is greater than the sum of
    their individual effects
    1 / 3
    2
  4. True or false. Schedule I drugs have a low abuse potential and are accepted
    medical use
    False via having a high abuse potential and no accepted medical use
  1. Ibuprofen: Antipyretic/NSAID Antihistamine: Sneezing/ runny nose/ Chlorphen
    Expectorant: Productive cough/ Gaifenesin Phenylephrine: Nasal Congestion/ Decongest
    Acetaminophen: Analgesic/antipyretic/ Pain/fever Dextromethorphan: Antitussive/Dry Cough
  2. True or False. The term antihistamine references drugs that block H1 Receptors
    True
    Drugs that block H2 receptors are simply called “H2 blockers
  3. Pantoprazole (Protonix, Nexium, Prilosec) PPI
    Milk of magnesia (Tums, Maalox) Antacid Neutralize gastric acid
    Famotidine (Pepcid, Tagment Zantac) H2 Receptor blockers Block H2 receptors in
    Antacids (Gaviscon) Neutralize gastric acid
  4. Carl 57-year-old male, has come to the clinic today for a standard wellness
    visit. The nurse asks Carl, what, if any, medications he is taking? He lists a
    medication typically associated with arthritis. The nurse has had many patients
    with Carl’s similar medical history also take glucosamine and chondroitin but fail
    to report taking these because they are not typical “medications”. What should
    the nurse discuss with Carl pertaining to supplementation use and reporting
    whether he takes them?
    He should disclose this, and know supplements are not safe via being natural. As
    dietary and herbal products can cause adverse effects, toxic effects, and allergic
    reactions just like prescription and OTC medications. And can also have drug
    interactions with other medications causing unwanted side effects.
  5. Which treatment for chronic heart failure works by decreasing blood volume,
    preload and workload required of the heart? ACE- inhibitors or ARBs

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