Fundamentals of Chemotherapy Immunotherapy Administration _ Questions And Answers
Fundamentals of Chemotherapy Immunotherapy Administration _
Questions And Answers
Hematologic cancer (blood cancer) Correct Ans ➡ -cancer that begins in bone
marrow or immune system cells.
-Ex: leukemia, lymphoma, multiple myeloma
Leukemia Correct Ans ➡ cancer starts in blood-forming tissues like bone
marrow
-causes lots of abnormal blood cells to be produced and enter bloodstream
Lymphoma Correct Ans ➡ -cancer that begins in immune system
(WBC=lymphocytes)
-hodgkin and non-hodgkins
-B lymphocytes (B cells) – make antibodies (bacteria and viruses, most common
lymphoma
-T lymphocytes (T cells) – boost/slow immune, destroy germs and abnormal cells
Hodgkin lymphoma Correct Ans ➡ Reed-Sternberg cell (cancer cells in classic)
-typically starts in B cells
Non-Hodgkin’s Lymphoma Correct Ans ➡ -large, diverse group of cancers in
immune system cells
-indolent (slow growing) or aggressive (fast)
Myeloma Correct Ans ➡ Cancer in plasma cells (WBC that produce antibodies)
Chemotherapy Correct Ans ➡ All antineoplastic agents used to treat cancer,
given through oral and parenteral routes or other routes as specified in the standard,
not including hormonal therapies.
Who can order chemotherapy? Correct Ans ➡ Written and signed by licensed
independent practitioners (MD/DO, PA, Oncology NP)
Can you use verbal orders for chemotherapy? Correct Ans ➡ NO! Only when
holding/stopping admin.
Who can mix Chemotherapy? Correct Ans ➡ Pharmacist, Pharmacy tech,
MD/DO, qualified RN
Who can administer chemotherapy? Correct Ans ➡ Registered Nurses with
specialized education, prep and training. See specific state laws and statutes
How often is chemo competency reassessed> Correct Ans ➡ Annual continuing
ed and competency assessment is recommended
What is the dose verification process? Correct Ans ➡ -confirm plan with patient
-two practitioners verify: drug name, dose, volume, rate, route, expiration date,
appearance
-document verification in chart
What PPE is required for IV Chemotherapy? Correct Ans ➡ -Gloves: two pairs,
HD tested
-Gown: disposable, back closed, long sleeved
-Respirator: NIOSH approved
-Eye & Face: face shield/mask
Neoadjuvant therapy (tumor burden) Correct Ans ➡ Chemo BEFORE primary
treatment (common in breast and colon)
Adjuvant therapy Correct Ans ➡ Chemo AFTER primary treatment (common in
solid tumor)
Bone Marrow Correct Ans ➡ soft, sponge-like tissue in center of most bones,
produce WBC, RBC, and platelets.
Myelosuppression Correct Ans ➡ bone marrow activity is decreased, causing
less RBC, WBC and Platelets.
Myeloablation Correct Ans ➡ severe myelosuppression
Induction phase Correct Ans ➡ initial phase, typically in hospital, intended
myelosuppression
Consolidation phase (intensification/postremission therapy) Correct Ans ➡ after
successful induction, kills cancer cells left in body (ex radiation, stem cell transplant)
Synergy Correct Ans ➡ when one chemo drug helps another work better at the
same time
Complete response Correct Ans ➡ no identifiable cancer present for at least
one month or longer
Partial response Correct Ans ➡ Measurable tumor reduced by 50% for at least
one month with no new tumors
Stable disease Correct Ans ➡ Tumor size reduced by less than 50% or less than
25% increase in growth
Progressive disease Correct Ans ➡ tumor growth more than 25% or new cancer
What are the phases of the cell cycle? Correct Ans ➡ -G1 phase
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