NR565 / NR565 Advanced Pharmacology Fundamentals Midterm / Final Exam| Questions and 100 % Correct Answers | Rated A Quiz bank | LATEST, 2020 / 2021 | Chamberlain College
NR565 / NR565 Advanced Pharmacology
Fundamentals Midterm / Final Exam|
Questions and 100 % Correct Answers |
Rated A Quiz bank | LATEST, 2020 /
2021 | Chamberlain College
- Kasey fractured his ankle in two places and is asking for medication for his pain. The
appropriate first-line medication would be:
- Acetaminophen with hydrocodone (Vicodin)
- Jack, age 8, has attention deficit disorder (ADD) and is prescribed methylphenidate
(Ritalin). He and his parents should be educated about the side effects of
methylphenidate, which are:
- Insomnia and decreased appetite
- Monitoring for a child on methylphenidate for attention deficit hyperactivity disorder
(ADHD) includes:
- ADHD symptoms
- Routine height and weight checks
- Amount of methylphenidate being used
- When prescribing Adderall (amphetamine and dextroamphetamine) to adults with ADHD
the nurse practitioner will need to monitor:
- Blood pressure
- Common mistakes practitioners make in treating anxiety disorders include:
- Thinking a partial response to medication is acceptable
- An appropriate first-line drug to try for mild to moderate generalized anxiety disorder
would be:
- Buspirone (Buspar)
- An appropriate drug to initially treat panic disorder is:
- Diazepam (Valium)
- Prior to starting antidepressants, patients should have laboratory testing to rule out:
- Hypothyroidism
- David is a 34-year-old patient who is starting on paroxetine (Paxil) for depression.
David’s education regarding his medication would include:
- He may experience sexual dysfunction beginning a month after he starts therapy.
- Jamison has been prescribed citalopram (Celexa) to treat his depression. Education
regarding how quickly selective serotonin reuptake inhibitor (SSRI) antidepressants work
would be:
- Appetite and concentration improve in the first 1 to 2 weeks.
- The racial difference in drug pharmacokinetics seen in American Indian or Alaskan
Natives are:
- Largely unknown due to lack of studies of this population
- Pharmacokinetics among Asians are universal to all the Asian ethnic groups.
A. True
B. False - Alterations in drug metabolism among Asians may lead to:
- Slower metabolism of antidepressants, requiring lower doses
- Asians from Eastern Asia are known to be fast acetylators. Fast acetylators:
- Require higher doses of drugs metabolized by acetylization to achieve efficacy
- Hispanic native healers (curanderas):
A. Are not heavily utilized by Hispanics who immigrate to the United States
B. Use herbs and teas in their treatment of illness
C. Provide unsafe advice to Hispanics and should not be trusted
D. Need to be licensed in their home country in order to practice in the United States - Genetic polymorphisms account for differences in metabolism, including:
- Poor metabolizers, who lack a working enzyme
- Intermediate metabolizers, who have one working, wild-type allele and one mutant
allele - Extensive metabolizers, with two normally functioning alleles
- Up to 21% of Asians are ultra-rapid 2D6 metabolizers, leading to:
- Increased dosages needed of drugs metabolized by 2D6, such as the selective
serotonin reuptake inhibitors
- Drugs that use CYP 3A4 isoenzymes for metabolism may:
- Induce the metabolism of another drug
- Inhibit the metabolism of another drug
- Rifampin is a nonspecific CYP450 inducer that may:
- Induce the metabolism of drugs, such as oral contraceptives, leading to therapeutic
failure
- Inhibition of P-glycoprotein by a drug such as quinidine may lead to:
- Increased levels of a co-administered drug, such as digoxin, that requires Pglycoprotein for absorption and elimination
- Warfarin resistance may be seen in patients with VCORC1 mutation, leading to:
- Decreased response to warfarin
- Genetic testing for VCORC1 mutation to assess potential warfarin resistance is required
prior to prescribing warfarin.
A. True
B. False - Pharmacogenetic testing is required by the U.S. Food and Drug Administration prior to
prescribing:
- Cetuximab
- Carbamazepine has a Black Box Warning recommending testing for the HLA-B*1502
allele in patients with Asian ancestry prior to starting therapy due to:
- Increased risk for Stevens-Johnson syndrome in Asian patients with HLA-B*1502
allele
- A genetic variation in how the metabolite of the cancer drug irinotecan SN-38 is
inactivated by the body may lead to
- Increased adverse drug reactions, such as neutropenia
- Patients who have a poor metabolism phenotype will have:
- Slowed metabolism of a prodrug into an active drug, leading to accumulation of
prodrug
- A patient’s nutritional intake and laboratory results reflect hypoalbuminemia. This is
critical to prescribing because:
- Distribution of drugs to target tissue may be affected.
- Drugs that have a significant first-pass effect:
- Are rapidly metabolized by the liver and may have little if any desired action
- The route of excretion of a volatile drug will likely be the:
- Lungs
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NR565 / NR565 Advanced Pharmacology Fundamentals Midterm / Final Exam| Questions and 100 % Correct Answers | Rated A Quiz bank | LATEST, 2020 / 2021 | Chamberlain College