WGU D115 Objective Assessment (Latest 2023/ 2024) Advanced Pathophysiology for the Advanced Practice Nurse|300+ Questions and Verified Answers|100% Correct
WGU D115 Objective Assessment: Advanced
Pathophysiology for the Advanced Practice
Nurse|300+ Questions and Verified
Answers|100% Correct
Q: A 17-year old female was diagnosed with angular cheilitis. She had treatment failure after a
course of topical antibiotics, topical steroids, moisture barrier creams, and antifungals were
prescribed. What would be the most appropriate next step in this patient’s plan of care?
A) Refer the patient to an allergist
B) Refer the patient to a dermatologist
C) Check the patient’s vitamin B12 level
D) Check the patient’s ferritin level
Answer:
C) Check the patient’s vitamin B12 level
Angular cheilitis is a condition that causes red, swollen patches in the corners of the mouth. The
most common cause is a fungal infection. Other causes are vitamin B12 deficiency and bacterial
infections.
Q: Which finding is most consistent with acute otitis externa?
A) Ringing in the affected ear
B) Hearing loss and drainage but no pain
C) Vertigo
D) pruritis and history of recent swimming
Answer:
D) pruritis and history of recent swimming
Otitis externa is a condition that causes inflammation (redness and swelling) of the external ear
canal.Otitis externa is often referred to as “swimmer’s ear” because repeated exposure to water
can make the ear canal more vulnerable to inflammation.
Q: An 15-year old male patient presents to the clinic with abdominal pain and fatigue, and is
diagnosed with infectious mononucleosis. Which is the most important part of this patient’s plan
of care?
A) He should not return to school until fever free for 48 hours
B) He should avoid contact sports for up to 4 weeks
C) He should complete a 10-day course of amoxicillin
D) He should be reassured that fatigue usually resolves in 5-7 days of onset
Answer:
B) He should avoid contact sports for up to 4 weeks
Because the spleen may become enlarged as a result of infectious mononucleosis, patients should
avoid contact sports until fully recovered. Participating in contact sports can be strenuous and
may cause the spleen to rupture.
Q: A 20-year old female reports a history of “cold symptoms” for 12 days. Her physical exam
reveals unilateral facial pain and purulent nasal discharge. Which diagnosis are these findings
consistent with?
A) Viral respiratory infection
B) Influenza B
C) Allergic Rhinitis
D) Acute Bacterial Rhinosinusitis
Answer:
D) Acute Bacterial Rhinosinusitis
Symptoms of acute bacterial rhinosinusitis include facial pain or pressure, postnasal drip, nasal
congestion, upper jaw or tooth pain, nasal discharge, fever, and cough. Symptoms are present for
10 days or longer.
Q: How is transcription best defined?
A) RNA is synthesized from a DNA template.
B) RNA directs the synthesis of polypeptides for protein synthesis.
C) A base pair substitution results in a mutation of the amino acid sequence
D) DNA polymerase binds to the promoter site on ribonucleic acid (RNA).
Answer:
A) RNA is synthesized from a DNA template.
Transcription is the process by which the information in a strand of DNA is copied into a new
molecule of messenger RNA (mRNA).
Q: An amniocentesis indicates a neural tube defect when an increase in which protein is
evident?
A) DNA polymerase
B) Embryonic proteins
C) Cytochrome P-450
D) Alpha fetoprotein
Answer:
D) Alpha fetoprotein
High levels of AFP may suggest the developing baby has a neural tube defect such as spina
bifida or anencephaly.
Q: Amniocentesis is recommended for pregnant with what history?
A) Have experienced in vitro fertilization
B) Have a history of chronic illness
C) Had a late menarche
D) Have a family history of genetic disorders
Answer:
D) Have a family history of genetic disorders
Amniocentesis is recommended for pregnant women 35 and older, women with a positive
prenatal screening test, chromosomal condition or neural tube defect in previous pregnancy,
family history of genetic disorders, or abnormal ultrasound results.
Q: What is the technique for prenatal diagnosis of chromosomal abnormalities at 10 to 12
weeks’ gestation?
A) Chorionic villus sampling
B) Amniocentesis
C) Linkage analysis
D) Gene mapping
Answer:
A) Chorionic villus sampling
Amniocentesis is usually performed during the 15th week of pregnancy or later. CVS is usually
performed between the 10th and 13th weeks of pregnancy.
Q: What is the term for an error in which homologous chromosomes fail to separate during
meiosis or mitosis?
A) Polyploidy
B) Nondisjunction
C) Aneuploidy
D) Translocation
Answer:
B) Nondisjunction
Nondisjunction means that a pair of homologous chromosomes has failed to separate or
segregate at anaphase so that both chromosomes of the pair pass to the same daughter cell. This
probably occurs most commonly in meiosis, but it may occur in mitosis to produce a mosaic
individual.
Q: What is the most common cause of Down syndrome?
A) Maternal nondisjunction
B) Maternal translocations
C) Paternal translocation
D) Paternal nondisjunction
Answer:
A) Maternal nondisjunction
Down syndrome is usually caused by an error in cell division called “nondisjunction.”
Nondisjunction results in an embryo with three copies of chromosome 21 instead of the usual
two. In the majority of cases, the extra copy of chromosome 21 comes from the mother in the
egg.
Q: What syndrome, characterized by an absent homologous X chromosome with only a single
X chromosome, exhibits features that include a short stature, widely spaced nipples, and webbed
neck?
A) Klinefelter
B) Cri du chat
C) Turner
D) Down
Answer:
C) Turner
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