Which of the following results in osteoporosis?
A.
An increase in osteocyte activity while osteoclast activity continues at expected levels.
B.
decline in osteoclast activity while osteoporosis activity reduces
C.
An increase in osteocyte activity while osteoblast activity reduces.
D.
A decline in osteoblast activity while osteoclast activity continues at expected levels
The correct answer is:
D. A decline in osteoblast activity while osteoclast activity continues at expected levels.
Explanation:
- A. An increase in osteocyte activity while osteoclast activity continues at expected levels: Osteocytes are mature bone cells that maintain bone tissue, and their activity alone does not typically cause osteoporosis. Osteoclasts are the cells that break down bone, but if their activity is normal, an increase in osteocyte activity would not directly lead to osteoporosis.
- B. Decline in osteoclast activity while osteoporosis activity reduces: A decline in osteoclast activity would actually help to reduce bone resorption, potentially decreasing the risk of osteoporosis, not causing it.
- C. An increase in osteocyte activity while osteoblast activity reduces: Osteocytes maintain bone but do not build new bone. A reduction in osteoblast activity (the cells responsible for bone formation) while osteocyte activity increases would contribute to osteoporosis because new bone formation is reduced.
- D. A decline in osteoblast activity while osteoclast activity continues at expected levels: Osteoblasts are responsible for bone formation. If osteoblast activity declines and osteoclast activity remains normal, bone formation decreases while bone resorption continues, leading to a net loss of bone mass, which results in osteoporosis.
Therefore, D. A decline in osteoblast activity while osteoclast activity continues at expected levels is the scenario that results in osteoporosis.