Which of the following results in osteoporosis?
A.
An increase in osteocyte activity while osteoclast activity continues at expected levels.
B.
A decline in osteoclast activity while osteoblast activity continues at expected levels.
C.
An increase in osteocyte activity while osteoblast activity continues at expected levels.
D.
A decline in osteoblast activity while osteoclast activity continues at expected levels.
The correct answer is:
D. A decline in osteoblast activity while osteoclast activity continues at expected levels.
Explanation:
Osteoporosis occurs when there is an imbalance between bone resorption and bone formation. Specifically:
- Osteoblasts are the cells responsible for bone formation.
- Osteoclasts are the cells responsible for bone resorption (breaking down bone tissue).
In osteoporosis, there is a decline in the activity of osteoblasts (which means reduced bone formation) while the activity of osteoclasts continues at normal levels. This imbalance leads to a net loss of bone density and strength, resulting in osteoporosis.