NaOCH3 is strong base and strong nucleophile. In d) CH3COONa is weak base and weak nucleophile. In e) NaSCH2CH3 is weak base and strong nucleophile.
The Correct Answer and Explanation is :
It seems the link you provided isn’t accessible for me to retrieve the content directly. However, I can still explain the concepts you mentioned related to base strength and nucleophilicity.
- NaOCH3 is a strong base and strong nucleophile because it has a negatively charged oxygen atom (high electron density) that can easily attack electrophilic carbon centers. Additionally, methoxide (CH3O−) is a strong base because it can deprotonate even relatively weak acids due to its high basicity.
- CH3COONa is a weak base and weak nucleophile. Acetate (CH3COO−) is less reactive in nucleophilic substitution due to its resonance structure, which distributes the negative charge over the oxygen and carbon, reducing its nucleophilicity. It’s also a weak base because it’s the conjugate base of a weak acid, acetic acid.
- NaSCH2CH3 is a weak base and strong nucleophile. Ethylthiolate (CH3CH2S−) is a stronger nucleophile than oxygen-based nucleophiles because sulfur is less electronegative than oxygen, making the negative charge more localized and reactive. However, it’s a weak base because thiolates are the conjugate bases of weak acids.
This differential reactivity is important in determining the reaction mechanism (e.g., SN1, SN2, E1, or E2) based on the choice of reagents. If you’d like further clarification or a more specific explanation, feel free to share more details!