Select the correct statement regarding tissue repair.
A) Granulation tissue is another name for a blood clot.
B) Granulation tissue is highly susceptible to infection.
C) The clot is formed from dried blood and transposed collagen fibers.
D) Inflammation causes capillaries to dilate and become more permeable.
The correct answer and explanation is :
The correct answer is D) Inflammation causes capillaries to dilate and become more permeable.
Explanation:
Tissue repair is a complex biological process that occurs after an injury to restore the integrity of the affected area. It involves several stages, including inflammation, tissue formation, and remodeling. Inflammation plays a crucial role in the early stages of tissue repair by promoting the healing process and preventing infection.
Option D is the correct statement because inflammation indeed causes capillaries (the smallest blood vessels) to dilate and become more permeable. When an injury occurs, inflammatory mediators such as histamines, prostaglandins, and bradykinin are released. These chemicals cause the blood vessels to expand (dilate) and increase their permeability, allowing immune cells (like neutrophils and macrophages) to enter the damaged tissue and clear out debris, bacteria, and dead cells. This process is essential for preventing infection and preparing the tissue for the next stages of repair.
Option A, “Granulation tissue is another name for a blood clot,” is incorrect. Granulation tissue is not a blood clot. Instead, it is a new tissue formed during the healing process, consisting of small blood vessels, collagen fibers, and fibroblasts. Blood clots, on the other hand, are formed primarily from platelets and fibrin to stop bleeding immediately after an injury.
Option B, “Granulation tissue is highly susceptible to infection,” is also incorrect. While granulation tissue is rich in blood vessels and serves as a foundation for healing, it is not inherently more susceptible to infection. In fact, the inflammation response helps protect it from infection by delivering immune cells to the area. However, infections can still occur if the immune system fails or if the wound is not properly managed.
Option C, “The clot is formed from dried blood and transposed collagen fibers,” is inaccurate. A blood clot is composed primarily of platelets and fibrin, not collagen fibers. Collagen fibers are involved later in the tissue repair process when granulation tissue begins to form and provide structural support to the regenerating tissue.
Thus, the correct understanding of tissue repair involves recognizing the critical role of inflammation in promoting capillary dilation and increased permeability for immune defense and repair.