A nurse is administering oral hydroxyzine to a client.

The Correct Answer and Explanation is:

Based on the visible text and standard pharmacological knowledge, the most appropriate answer is:

Sore throat

Explanation

Hydrocortisone is a potent corticosteroid medication used for its strong anti inflammatory and immunosuppressive effects. When a client receives intravenous hydrocortisone, the drug acts systemically, affecting the entire body. One of the most significant and potentially dangerous adverse effects of corticosteroid therapy is immunosuppression.

The drug works by inhibiting the body’s immune response. This action, while beneficial for treating inflammatory conditions, leaves the client highly vulnerable to infections from various pathogens, including bacteria, viruses, and fungi. A critical aspect of corticosteroid use is that these medications can also mask the classic signs of an infection. For example, a patient on hydrocortisone might not develop a fever, significant swelling, or redness even when a serious infection is present. This masking effect can delay diagnosis and treatment, allowing the infection to become severe or even life threatening.

For this reason, it is essential for the nurse to educate the client on reporting any subtle signs of a potential infection. A sore throat is a primary example of such a sign. It could indicate the onset of an upper respiratory infection or a fungal infection like oral candidiasis (thrush). Prompt reporting allows for early intervention and treatment, which is crucial when the body’s natural defenses are compromised. While other adverse effects like hyperglycemia (which can cause polyuria, or increased urination) can occur, the immediate risk posed by a masked and uncontrolled infection makes reporting a sore throat a top priority for patient safety. Hearing loss and bronchospasm are not common adverse effects of hydrocortisone.

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