NURS-6630N-5/NURS-6630C5/NURS-6630F-5/DNRS- 6630F
Approaches to Treatment-2021-
Summer Final Exam – Week 11
Attempted Score 92 out of 100 points
Question 1
L. J. is a 55-year-old male who attended a funeral and found himself laughing during
the service, but later that evening he was irritated with himself for what he had done. His
wife said this was abnormal behavior and took him to his doctor to be evaluated. After L.
J.’s MRI was reviewed, he was diagnosed with frontotemporal dementia. Which
medication is recommended to help L. J. with his emotional outbursts?
A. Memantine
B. Escitalopram
C. Donepezil
D. Risperidone
Response Feedback: under Treatment subtitle: ―The behavioral features are
sometimes helped by SSRIs, and these are the best-studied treatments for these
disorders.‖
Question 2
When can buprenorphine be initiated in a patient who is suffering from an opioid
overdose?
A. As soon as the patient is stabilized
B. It should be administered as soon as you find the patient unconscious
C. Right after naloxone is administered to prevent the patient from going back into
opioid overdose
D. When the patient is experiencing mild-to-moderate symptoms of withdrawal
Response Feedback: ―To avoid this problem, the initial buprenorphine dose should not
be administered until the patient demonstrates mild-to-moderate symptoms of
withdrawal.‖
Question 3
Of the following neurotransmitters, which one(s) are known to be severely disrupted in
the disease Dementia with Lewy Bodies?
I. Acetylcholine
II. Glutamate
III. Dopamine
IV. GABA
V. Norepinephrine
A. II only
B. III only
C. I and II
D. I and III
Response Feedback: under pathophysiology subtitle: ―It is clear that both the
cholinergic and dopaminergic neurotransmitter systems are severely disrupted.‖
Question 4
Choose the correct statement regarding medications used for alcoholism
A. Disulfiram: NMDA receptor antagonist & GABAA agonist
B. Naltrexone: µ-opioid receptor antagonist that reduces the reinforcement/euphoria
produced by alcohol
C. Acamprosate: enhances the effect of the inhibitory neurotransmitter
gammaaminobutyric acid on the GABA receptors by binding to a site that is distinct from
the GABA binding site in the central nervous system.
D. Lorazepam: inhibits alcohol dehydrogenase, leading to a buildup of acetaldehyde
Response Feedback: Table 15-3 has the three MOAs listed for the FDA-approved
treatments of alcoholism.
Question 5
Patient is a 75-year-old female with a confirmed diagnosis of Alzheimer’s Disease. She
is currently on Donepezil 10 mg daily. She is accompanied to your clinic today by her
daughter, who informs you that her mother has recently had an increase in depressive
symptoms. She has no history of mood disorders. She has a history of hypertension
and tonic-clonic seizures, but both are controlled. Assuming this patient will be
thoroughly evaluated for the diagnosis of depression, what would you recommend as
initial therapy?
A. Amitriptyline
B .Doxepin
C .Fluoxetine
D. Bupropion
Response Feedback: SSRIs are effective in treating depressive symptoms. Answer
choices A & B are both TCAs and are advised against due to side effect profile and the
fact this person is treatment naive (learned from previous exam) and answer choice D is
contraindicated in a patient with seizures.
Question 6
Which neurotransmitters are likely involved in the pathophysiology of withdrawal
seizures?
I. Serotonin
II. Endorphins
III. Glutamate