1
Pharmacology NURS 251 Final Exam
1.
Sublingual: When rapid effect is needed right away
Subcutaneous: Destroy or inactivated in the GI Tract
Intramuscular: Used for drugs with poor oral absorption
Topical: For local effects on skin and eyes
Pharmaceutics is the study of how various dosage forms influence the way in
which the drug affects the body/ Administration of dosage form, dissolution of
drug into body/ manipulating chemical compound.
Pharmacokinetics is the study of what the body does to the drug, including
absorption, distribution, metabolism, and excretion/ Absorption, distribution,
metabolism, excretion.
Pharmacodynamics is the study of what the drug does to the body/ Drugreceptor interaction.
- The drug naltrexone is given to prevent relapse or cravings in individuals who
use opioids. It binds to opioid receptors blocking endogenous agonist and other
opioid drugs from binding and having an effect. Naltrexone is a/an
Competitive agonist (binds to the same site of agonist) - Due to the many chronic diseases associated with aging the elderly can have
decreased blood flow to the liver. With age, there can also be a decrease in liver
enzymes, which can increase the duration of a drug in the patient’s systems.
Which pharmacokinetic process is affected in this scenario?
Metabolism (stored in the body)/ cytochrome P-450 enzymes/ liver/ Grapefruit
and statins - When the combined effect of two drugs is greater than the sum of the
individual effects it refers to
Synergism: When the combined effect of two drugs is greater than the sum of
their individual effects
2
- True or false. Schedule I drugs have a low abuse potential and are accepted
medical use
False via having a high abuse potential and no accepted medical use - Michael is a 2 year old male with a history of a liver cirrhosis problem caused by
biliary atresia. While on a family vacation, Michael developed a fever, and his
parents found children’s Motrin as the only antipyretic option at eh hotel
convenience shop. Is this an appropriate for Michael? Explain why or why not.