Exam 3: NURS660/ NURS 660 (Latest 2023/
2024) Psychopharmacology and Advanced
Mental Health Exam| Complete guide with
Questions and Verified Answers| 100%
Correct – Maryville
Q: What is central neuropathic pain or central sensitization due to?
Answer:
central disturbance in pain processing (diffuse hyperalgesia/ allodynia
Q: What does central neuropathic pain or central sensitization respond to?
Answer:
neuroactive compounds that alter levels of neurotransmitters involved in pain transmission, and
responsive to nonpharmacologic therapies such as exercise and CBT
Q: What are examples of central neuropathic pain/ central sensitization?
Answer:
Fibromyalgia, IBS, TMJD, Tension headache
Q: What is the combination of peripheral and central mechanism pain due to?
Answer:
involvement of both inflammatory or mechanical damage to the tissues along with dysfunction in
central pain processing
Q: How to treat a combination of peripheral and central mechanism-related pain
Answer:
need to treat all contributing mechanisms
Q: Give examples of combination of peripheral/ central mechanism pain
Answer:
low back pain, Rheumatologic diseases that develop into comorbid fibromyalgia
Q: List the Benzodiazepine Anxiolytics
Answer:
Xanax, Valium, Ativan
Q: List the labs for Benzodiazepine Anxiolytics
Answer:
Monitor levels of TCA and Dig with concurrent use of Benzos–may increase those levels. Long
term: check liver and CBC periodically.
Q: Mech of Action of Benzodiazepine Anxiolytics
Answer:
Binds to benzo receptors on postsynaptic GABA-A neuron within CNS including limbic system
Q: In case of Benzo OD, use what med?
Answer:
Flumazinil
Q: Pregnancy Risk for Benzo’s
Answer:
Contraindicated
Q: What is a non-Benzo Anxiolytic?
Answer:
Buspar
Q: On what Neurotransmitters does Buspar work?
Answer:
5HT1A and 5HT2 receptors, does not affect GABA receptors, moderate affinity for D2
receptors. 5HT1A partial agonist at pre and post synaptic receptors
Q: Mechanism of action of Buspar
Answer:
Enhanced serotonergic activity in projections to the amygdala, PFC, Striatum, and thalamus
Q: Side Effects of Buspar
Answer:
Light headedness, headache, insomnia, nausea, nervousness/restlessness
Exam 4: NURS660/ NURS 660 (Latest 2023/
2024) Psychopharmacology and Advanced
Mental Health Exam| Complete guide with
Questions and Verified Answers| 100%
Correct – Maryville
Q: Amphetamine/dextroamphetmamine
Answer:
Adderall
Q: Adderall (amphetamines)/Ritalin (methylphenidate) works by increasing
Dopamine/Norepinephrine?
Answer:
Aderall (amphetamines)
Q: Adderall/Ritalin competitively inhibits Dopamine transporter?
Answer:
Adderall
Q: Adderall/Ritalin works with VMAT?
Answer:
Adderall
Q: Adderall/Ritalin directly leads to release of Dopamine by displacing
Dopamine molecules from Vesicle sites?
Answer:
Adderall
Q: Adderall/Ritalin works similar to SSRI?
Answer:
Ritalin
Q: Adderall/Ritalin blocks reuptake of Dopamine into the terminal?
Answer:
Ritalin
Q: Adderall/Ritalin blocks reuptake of Norepinephrine into the terminal?
Answer:
Ri- talin
Q: Adderall/Ritalin does not lead to release of Dopamine, but makes it more available?
Answer:
Ritalin
Q: Adderall/Ritalin/Strattera – ED or decreased libido
Answer:
Strattera
Q: Adderall/Ritalin/Strattera – constipation
Answer:
Strattera
Q: Adderall/Ritalin/Strattera – jitteriness
Answer:
Adderall/Ritalin
Q: Adderall/Ritalin/Strattera – increase in BP
Answer:
Adderall/Ritalin
Q: Adderall/Ritalin/Strattera – liver damage
Answer:
Strattera
Q: Adderall/Ritalin/Strattera – anxiety, panic
Answer:
Adderall/Ritalin
Q: Atomoxetine
Answer:
Strattera
Q: Atomoxetine (Strattera) works by blocking?
Answer:
Exam 3: NURS660/ NURS 660 (Latest 2023/
2024) Psychopharmacology and Advanced
Mental Health Exam| Questions and Verified
Answers| Grade A – Maryville
Q: Types of pain that is treated with psychiatric medication
Answer:
protracted pain
(mix of nociceptive and central pain and chronic pain (central)
Q: effect of how antidepressants migrate pain – Direct (way you think about pain)
Answer:
increase in supraspinal inhibition and decrease peripheral and central desen- sitization
Q: effect of how antidepressants migrate pain- Indirect (way you feel about pain)
Answer:
modulate limbic activity and prefrontal structures
Q: What is mincitolapram
Answer:
SNRI prescribed to treat fibromyalgia
Q: Antidote for alprazolam
Answer:
flumazenil
Q: MOA of pregabalin
Answer:
1.alter GABA metabolism
2.bind to subunit of voltage-gated Ca channel to reduce NT release
Q: What is the antagonist of caffeine
Answer:
adenosine
Q: s/s general anxiety disorder -4
Answer:
excessive worrying, increased arousal, in- creased tiredness and irritability
Q: Arears of brain that are involved with fear, anxiety and fight or flight
Answer:
amyg- dala and hippocampus
Q: MOA of modafinil
Answer:
Non-amphetamine stimulant > enhances dopaminergic sig- naling; enhances tonic dopamine
firing (1st line tx for narcolepsy)
Q: what receptors does eszopiclone target
Answer:
binds to the GABA-a receptor sub- units 1, 3, and 5
Q: first line treatment for PTSD
Answer:
SSRI – sertraline and paroxetine
Q: medication used to help cognitive and physical symptoms of firomyalgiaAnswer:
milnacipran (Savella)
Q: During a panic attack what area of the brain is related to SOB and tachy- cardia
Answer:
pararachial nucleus
Q: what non-addictive medication can be used to aide in sleep induction
Answer:
su- vorexant (belsomra)
Q: How does Suvorexant work?
Answer:
blocks the action of orexin. Orexin is a chemical in the brain that plays a role in the sleep cycle
and promotes wakefulness.
Q: what receptor does buspirone primarily act upon
Exam 4: NURS660/ NURS 660 (Latest 2023/
2024) Psychopharmacology and Advanced
Mental Health Exam| Questions and Verified
Answers| Grade A – Maryville
Q: A patient diagnosed with ADHD can’t stay focused or solve work-related problems
difficulty maintaining attention sustained and problem-solving. What area of the brain is
involved?
Answer:
Dorsal lateral prefontal cortex (CTSC loop)
Q: What part of the brain is associated with selective attention?
Answer:
Dorsal anterior singlunate
Q: What part of the brain is associated with hyperactivity?
Answer:
Prefrontal motor cortex
Q: What part of the brain is associated with impulsivity?
Answer:
Orbitofrontal cortex
Q: Atomoxetine (Strattera) lacks abuse potential because of what
Answer:
increases dopamine in the dorsal prefrontal cortex and not in the nucleus accumbens
Q: What fetal malformation does valproate cause?
Answer:
Spina bifida
Q: What region of the brain is hypothesized to cause impulsivity?
Answer:
ventral striatum
Q: What region of the brain controls compulsivity?
Answer:
Dorsal striatum
Q: What is the MOA of atomoxetine?
Answer:
Selective Norepinephrine Reuptake Inhibitor: Boosts neurotransmitter norepinephrine/
noradrenaline and may also increase dopamine in profrontal cortex • Blocks norepinephrine
reuptake pumps, also known as norepinephrine transporters •
Q: Amaloid precursor protein is first cleaved by what enzyme
Answer:
Alpha-secretase
Q: What does paroxetine do to Straterra in the body?
Answer:
increases the effect of the drug in the body
Q: If a patient is taking paroxetine and starts Straterra what should change about the Straterra
dose?
Answer:
The dose should be decreased
Q: An Alzheimer’s patient has been taking 4mg of rivastigmine what side effects might you
anticipate and why?
Answer:
GI side effects; inhibits peripheral uptake of ACH and butyrycholine
Q: Which neurotransmitters lead to eurphoria and abuse in a patient with marijuana abuse and
ADHD.
Answer:
Pulsatile delivery of stimulants can cause a frequent and rapid delivery amplifying phasic firing
of NE and DA. Phasic firing is associated with reward, euphoria, and abuse
Q: A child is diagnosed with ADHD, what symptoms continue into adulthood?