- The cardiovascular system…
(A)Aids in the transfer of heat energy from organs deep within the body to the outside environment
(B) Comprises pulmonary and systemic circulations that are in parallel with each other
(C) Transports carbon dioxide from the lungs to tissues within organs
(D)Transports oxygen from individual cells to the lungs - Cardiac output of the right side of the heart is what percentage of the cardiac output of the left side of
the heart?
(A)25% (B) 50% (C) 75% (D)100% (E) 125% - A 22-year-old man with no history of congenital heart disease has a normal physical examination prior
to entering the military. Which of the following characteristics is most similar in the systemic and
pulmonary circulations of this patient?
(A)Preload
(B) Afterload
(C) Peak systolic pressure
(D)Blood volume
(E) Stroke work - A patient with valve disease undergoes cardiac catheterization to compare vascular and intracardiac
pressures against normal values. Which of the following is found in a heart with normal valve function?
(A)Aortic diastolic pressure is less than pulmonary artery systolic pressure
(B) Left ventricular end-diastolic pressure is less than mean right atrial pressure
(C) Mean left atrial pressure is normally greater than mean right atrial pressure by < 10 mm Hg
(D)Pulmonary artery diastolic pressure is less than mean right atrial pressure - The greatest pressure decrease in the circulation occurs across the arterioles because…
(A)They have the greatest surface area
(B) They have the greatest cross-sectional area
(C) The velocity of blood flow through them is the highest
(D)The velocity of blood flow thorough them is the lowest
(E) They have the greatest resistance - At which site is systolic blood pressure the highest?
(A)Aorta
(B) Central vein
(C) Pulmonary artery
(D)Right atrium
(E) Renal artery
(F) Renal vein - Which of the following statements concerning the heart is true?
(A)Cardiac output is the product of ventricular stroke volume and heart rate
(B) The right and left ventricles are in parallel
(C) The right ventricle generates higher pressures than the left ventricle during contraction
(D)The right ventricle receives blood from the pulmonary veins - In a recumbent person, the greatest difference in blood pressure exists between the…
(A)Ascending aorta and brachial artery
(B) Saphenous vein and right atrium
(C) Femoral artery and femoral vein
(D)Pulmonary artery and left atrium
(E) Arteriolar and venous ends of a capillary - During ventricular ejection, the pressure difference smallest in magnitude is between which of the
following?
(A)Pulmonary artery and left atrium
(B) Right ventricle and right atrium
(C) Left ventricle and aorta
(D)Left ventricle and left atrium
(E) Aorta and capillaries - The greatest resting arteriovenous difference in O2 content is found in the…
(A)Liver
(B) Skeletal muscle
(C) Heart
(D)Kidney
(E) Lung - Which of the following organs has the highest arteriovenous O2 difference under these normal resting
conditions?
(A)Brain
(B) Heart
(C) Skeletal muscle
(D)Kidney
(E) Liver
ANS and CVS - The cell bodies for the preganglionic vagal efferents innervating the heart are found in which region of
the brain?
(A)Cortex
(B) Hypothalamus
(C) Medulla
(D)Nucleus tractus solitarius - Norepinephrine released by sympathetic nerves…
(A)Binds preferentially to β-adrenoceptors on cardiac myocytes
(B) Constricts blood vessels by binding to α1-adrenoceptors
(C) Inhibits its own release by binding to prejunctional β2-adrenoceptors
(D)Decreases renin release in the kidneys - Which receptor mediates constriction of arteriolar smooth muscle?
(A)α1 receptors
(B) β1 receptors
(C) β2 receptors
(D)M receptors
(E) N receptors - Stimulating efferent fibers of the right vagus nerve…
(A)Decreases systemic vascular resistance
(B) Increases atrial inotropy
(C) Increases heart rate
(D)Releases acetylcholine, which binds to M2
receptors
2 / 4 - Which receptor mediates slowing the heart?
(A)α1 receptors
(B) β1 receptors
(C) β2 receptors
(D)M receptors
(E) N receptors - In a study of the carotid sinus reflex, a fellow classmate vigorously massages the area over the carotid
sinus. Which one of the following events might be expected to result from this exercise?
(A)An increase in aortic blood pressure and heart rate
(B) A decrease in heart rate and aortic pressure
(C) A decrease in blood pressure and an increase in heart rate
(D)An increase in respiratory rate and depth
(E) A decrease in respiratory rate and depth - A 42-year-old woman with lightheadedness and recurrent syncope is taken to the emergency
department where she is given atropine. Her symptoms are relieved by an increase in which of the
following?
(A)Heart rate
(B) PR interval
(C) Ventricular contractility
(D)Ejection fraction
(E) Stroke volume - Propranolol has which of the following effects?
(A)Decreases heart rate
(B) Increases left ventricular
ejection fraction
(C) Increases stroke volume
(D)Decreases splanchnic
vascular resistance
(E) Decreases cutaneous
vascular resistance - When propranolol is administered, blockade of which receptor is responsible for the decrease in cardiac
output that occurs?
(A)α1 receptors
(B) β1 receptors
(C) β2 receptors
(D)M receptors
(E) N receptors - A patient in circulatory shock is treated with norepinephrine to raise arterial pressure by stimulating the
heart through β-adrenoceptor activation and constricting blood vessels through α-adrenoceptor
activation. The cardiac and vascular effects can be explained by…
(A)Increased cardiac cAMP and increased vascular cGMP
(B) Increased cardiac cAMP and increased vascular IP3
(C) Increased cardiac and vascular cAMP
(D)Increased cardiac IP3 and increased vascular cAMP - Infusion of a high dose of epinephrine following pharmacologic blockade of β-adrenoceptors will…
(A)Decrease mean arterial pressure
(B) Have no significant cardiovascular effects
(C) Increase heart rate
(D)Increase systemic vascular resistance - Sympathetic stimulation during exercise has which of the following cardiac effects?
(A)An increased in the duration of systole
(B) An increase in the duration of diastole
(C) An increase in the activity of the SR Ca2+-ATPase
(D)A decrease in the concentration of Ca2+ during systole
Cellular Physiology (Action Potentials) of CVS - Vascular smooth muscle contraction is enhanced by…
(A)Activation of myosin light chain kinase
(B) Activation of myosin light chain phosphatase
(C) Calcium binding to troponin-C
(D)Dephosphorylation of myosin light chains - Thick filaments within cardiac myocytes contain…
(A)Actin (B) Myosin (C) Tropomyosin (D)Troponin - During excitation-contraction coupling in cardiac myocytes,
(A)Calcium binds to myosin causing ATP hydrolysis
(B) Calcium binds to troponin-I
(C) Myosin heads bind to actin
(D)SERCA pumps calcium out of the sarcoplasmic reticulum - The low-resistance pathways between myocardial cells that allows for the spread of action potentials
are the…
(A)Gap junctions
(B) T tubules
(C) Sarcoplasmic reticulum
(D)Intercalated disks
(E) Mitochondria - Which one of the following depolarizes the resting membrane potential in a cardiac myocyte?
(A)Decreased calcium conductance
(B) Decreased sodium conductance
(C) Increased potassium conductance
(D)Inhibition of the sarcolemmal Na+
/K+
- ATPase
- Which of the following is the result of an inward Na+ current?
(A)Upstroke of the action potential in the SA node
(B) Upstroke of the action potential in Purkinje fibers
(C) Plateau of the action potential in ventricular muscle
(D)Repolarization of the action potential in ventricular muscle
(E) Repolarization of the action potential in the SA node
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