NR 566 Advanced Pharmacology for
Care of the Family
Which anticonvulsant would be given for someone with epilepsy needing
adjunctive therapy for partial seizures with or without secondary
generalization?
Correct Answer:
Lamotrigine
Preventive therapy for migraines headache
Correct Answer:
Metoprolol/propranolol (Beta-blockers) are often used as preventive therapy
What is abortive therapy for migraines headache and when is it used?
Correct Answer:
Abortive medications stop a migraine when pt feels one coming or once it
has begun.
NSAIDS and opioid and migraine-specific meds (Triptans and Ergot
alkaloids)
used at 1st sign of attack
1st line treatment for acute, mild to moderate migraine without nausea or
vomiting
Correct Answer:
NASID: Naproxen and ASP
How to know someone would be appropriate for preventative therapy for
migraine headache
Correct Answer:
Patients who have frequent attacks 3 or more, severe attacks, or attacks
that do not respond adequately to abortive therapy
Examples of opioid analgesics reserved for severe migraines that don’t
respond to first-line medications
Correct Answer:
Butorphanol nasal spray
use one spray each nostril every 60 minutes PRN
the mechanism of action for sumatriptan
Correct Answer:
Suppresses the release of CGRP from trigeminal neurons, which leads to
vasoconstriction and decreased perivascular inflammation to relieve migraine
pain
Triptans contraindications
Correct Answer:
History of ischemic heart disease, uncontrolled hypertension,
cerebrovascular disease, pregnancy, basilar or hemiplegic migraine; use
within 24 hours of an ergot derivative
The first dose of triptan should be
Correct Answer:
under direct supervision case of any unknown underlying cardiac disease
Rivastigmine (Exelon) patient teaching
Correct Answer:
can cause bradycardia, fainting, fall, and fall-related fractures.
family teaching how to prevent fall at home
Donepezil (Aricept)
when would it be appropriate to increase the dose?
Correct Answer:
patient are stabilized on the initial dosage for 1 to 3 months before an
increased in dosage
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