A client with ascites is prescribed spironolactone, a potassium-sparing diuretic.

A client with ascites is prescribed spironolactone, a potassium-sparing diuretic. The nurse instructs the client to monitor for which of the following adverse effects while taking this medication?
A.
Muscle weakness and fatigue.

B.
Increased urine output and dehydration.

C.
Hypotension and dizziness.

D.
Hyperkalemia and irregular heart rhythms.

The Correct answer and Explanation is:

The correct answer is D. Hyperkalemia and irregular heart rhythms.

Spironolactone is a potassium-sparing diuretic commonly prescribed to manage fluid retention, particularly in conditions like ascites, heart failure, and hypertension. Unlike other diuretics that can lead to potassium loss, spironolactone retains potassium in the body. Therefore, one of the significant risks associated with its use is hyperkalemia, a condition characterized by elevated levels of potassium in the blood.

Patients taking spironolactone need to be vigilant about their potassium levels because hyperkalemia can lead to serious complications, including irregular heart rhythms (arrhythmias). Elevated potassium levels can disrupt the normal electrical conduction of the heart, which can be life-threatening. Symptoms of hyperkalemia may include muscle weakness, fatigue, palpitations, and changes in heart rhythm, which the nurse should instruct the patient to report immediately.

Monitoring for muscle weakness and fatigue (Option A) is important as they can be symptoms of hyperkalemia; however, they are not the primary adverse effects to monitor for while on spironolactone alone. Increased urine output and dehydration (Option B) are more common with other types of diuretics and are not specific concerns for potassium-sparing diuretics like spironolactone. Hypotension and dizziness (Option C) can occur but are not as closely associated with spironolactone as hyperkalemia is.

Overall, educating the client about the signs and symptoms of hyperkalemia, the importance of regular blood tests to monitor potassium levels, and lifestyle modifications, such as avoiding high-potassium foods or potassium supplements, is essential in managing their therapy effectively and safely.

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