The reaction shown can give two different mono-alkylation products depending on the conditions. Draw the kinetic and thermodynamic products of the reaction. 1. base Kinetic + Thermodynamic Products 2. CH,CH,Br (1 equiv.) Draw the kinetic product Draw the thermodynamic product. Select Draw Rings More Select Draw Rings More Erase Erase // H o ? H 0
The Correct Answer and Explanation is :
The reaction you are describing seems to be an alkylation reaction involving a base and an alkyl halide (CH₃CH₂Br). In this context, the reaction can yield two distinct products, based on whether the reaction conditions favor the kinetic or thermodynamic product.
1. Kinetic Product:
The kinetic product is formed under conditions that favor the fastest pathway, typically at lower temperatures. The base attacks the most accessible carbon on the substrate. In the case of CH₃CH₂Br, this would be the carbon attached to the bromine in the primary position. A strong base would favor a fast deprotonation at this site, resulting in the alkylation of the least sterically hindered position.
The kinetic product will likely result in the formation of a more substituted, less stable alkene (like a primary or secondary alkylated product). The key characteristic of the kinetic product is that it forms more quickly but is not necessarily the most stable product.
2. Thermodynamic Product:
The thermodynamic product is favored at higher temperatures or in the presence of a weaker base. Under these conditions, the reaction is governed by the stability of the product. In this case, the base would attack the carbon on the alkyl halide that leads to the most stable, most substituted alkylated product. This would typically be a more substituted carbon center (secondary or tertiary). The thermodynamic product is favored because it is more stable due to the greater hyperconjugation and inductive effects from more substituted carbon atoms.
Summary of Products:
- Kinetic product: A product that forms faster, usually the primary alkylation.
- Thermodynamic product: A more stable product, typically a more substituted alkylated product.
For this reaction, depending on the reaction conditions (temperature and base strength), you will either favor the faster-forming kinetic product or the more stable thermodynamic product.