{"id":112566,"date":"2023-08-15T18:36:29","date_gmt":"2023-08-15T18:36:29","guid":{"rendered":"https:\/\/learnexams.com\/blog\/?p=112566"},"modified":"2023-08-15T18:36:33","modified_gmt":"2023-08-15T18:36:33","slug":"wgu-d027-oa-exam-2023-2024-actual-exam-test-bank-400-questions-and-correct-detailed-answers-with-rationalesagrade","status":"publish","type":"post","link":"https:\/\/www.learnexams.com\/blog\/2023\/08\/15\/wgu-d027-oa-exam-2023-2024-actual-exam-test-bank-400-questions-and-correct-detailed-answers-with-rationalesagrade\/","title":{"rendered":"WGU D027 OA EXAM 2023-2024 ACTUAL EXAM TEST BANK 400 QUESTIONS AND CORRECT DETAILED ANSWERS WITH RATIONALES|AGRADE"},"content":{"rendered":"\n<p>WGU D027 OA EXAM 2023-2024 ACTUAL EXAM TEST BANK<br>400 QUESTIONS AND CORRECT DETAILED ANSWERS WITH<br>RATIONALES|AGRADE<br>What are some physical changes from Alzheimer&#8217;s dementia? &#8211; ANSWER- &#8211; Brain<br>shrinks dramatically; nerve cell death and tissue loss<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Cardinal signs: plaques (abnormal clusters of protein fragments) and tangles<br>(twisted strands of another protein)<br>How is Alzheimer&#8217;s treated? &#8211; ANSWER- &#8211; There is no cure, but there are<br>pharmacological and non-pharmacological treatments<\/li>\n\n\n\n<li>Cholinesterase inhibitors<\/li>\n\n\n\n<li>Memantine (namenda)<br>What are cholinesterase inhibitors prescribed for? &#8211; ANSWER- &#8211; To treat<br>symptoms related to memory, thinking, language, judgment, and other processes<\/li>\n\n\n\n<li>Helps delay or slow the worsening of symptoms<br>What does cholinesterase inhibitors do? &#8211; ANSWER- &#8211; Prevent the breakdown of<br>acetylcholine, a chemical messenger that is important for learning and memory<\/li>\n\n\n\n<li>Supports communication among nerve cells by keeping the acetylcholine high<br>What are some commonly prescribed cholinesterase inhibitors? &#8211; ANSWER- &#8211;<br>Donepezil (aricept)<\/li>\n\n\n\n<li>Galantamine (razadyne)<\/li>\n\n\n\n<li>Rivastigmine (exeleon)<br>Which cholinesterase inhibitor can be used for all stages of Alzheimer&#8217;s? &#8211;<br>ANSWER- &#8211; Donepezil (aricept)<br>Which cholinesterase inhibitor can be used for mild-to-moderate stages of<br>Alzheimer&#8217;s? &#8211; ANSWER- &#8211; Galantamine (razadyne)<\/li>\n\n\n\n<li>Rivastigmine (exeleon)<br>Which cholinesterase inhibitor can be used for mild-to-moderate Alzheimer&#8217;s and<br>Parkinson&#8217;s? &#8211; ANSWER- &#8211; Rivastigmine (exeleon)<\/li>\n<\/ul>\n\n\n\n<p>What medication combination is used to treat moderate-to-severe Alzheimer&#8217;s? &#8211;<br>ANSWER- &#8211; Memantine (namenda) and donepezil (aricept)<br>What is memantine (namenda) used for? &#8211; ANSWER- &#8211; Prescribed to improve<br>memory, attention, reason, language, and the ability to perform simple tasks<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Can be used alone or with other Alzheimer&#8217;s disease treatments<br>How does memantine (namenda) work? &#8211; ANSWER- &#8211; Regulates the activity of<br>glutamate, a chemical involved in information processing, storage, and retrieval<\/li>\n\n\n\n<li>Improves mental functioning and ability to perform daily activities for some<br>people<br>What is the difference in MOA between cholinesterase inhibitors and memantine<br>(namenda)? &#8211; ANSWER- &#8211; Cholinesterase inhibitors prevent the breakdown of<br>acetylcholine, whereas memantine (namenda) regulates the activity of glutamate<br>What is ataxia? &#8211; ANSWER- &#8211; Also known as cerebellum attacks<\/li>\n\n\n\n<li>Degenerative disease of the nervous system<\/li>\n\n\n\n<li>Many symptoms mimic those of being drunk (i.e. slurred speech, stumbling,<br>falling, and incoordination)<br>What causes the symptoms of ataxia? &#8211; ANSWER- &#8211; The damage caused to the<br>cerebellum, the part of the brain that is responsible for coordinating movements<\/li>\n\n\n\n<li>Can also be caused by damage to part of the spinal cord and nerves<br>What is the treatment for ataxia? &#8211; ANSWER- &#8211; No treatment<\/li>\n\n\n\n<li>In some cases, treating the underlying causes (i.e. stopping medications that cause<br>ataxia)<\/li>\n\n\n\n<li>In other cases, it is a result from chicken pox or other viral infections (likely to<br>resolve on its own)<\/li>\n\n\n\n<li>Genetic causes\/predisposed disposition is usually chronic<br>What causes ataxia in the pediatric population? &#8211; ANSWER- &#8211; Genetic<br>predisposition<\/li>\n\n\n\n<li>Fragile X-Associated Tremor\/Ataxia Syndrome (FXTAS)<\/li>\n\n\n\n<li>Prader-Willie Syndrome<br>What is Fragile X syndrome (FXS)? &#8211; ANSWER- &#8211; A genetic condition inherited<br>from parents which results in various developmental problems<\/li>\n\n\n\n<li>Rare, but may be dangerous or life-threatening<\/li>\n\n\n\n<li>Present at birth and is a lifelong condition<\/li>\n\n\n\n<li>Rarely requires lab testing or imaging<\/li>\n\n\n\n<li>Often linked to autism (1\/3 do have autism)<\/li>\n\n\n\n<li>X-linked disorder<br>Since Fragile X Syndrome (FXS) is an X-linked disorder, does a specific gender<br>have a greater risk? &#8211; ANSWER- &#8211; Often, females are carriers and males are<br>affected<\/li>\n\n\n\n<li>However, both males and females can be carriers, and both can be affected by the<br>condition<\/li>\n\n\n\n<li>Usually milder in females<br>How did Fragile X Syndrome (FXS) get its name? &#8211; ANSWER- &#8211; The gene Fragile<br>X (the FMR1 gene) is on the X syndrome<\/li>\n\n\n\n<li>Mutation of the FMR1 gene<br>What is the difference between Fragile X-Associated Tremor\/Ataxia Syndrome<br>(FXTAS) and Fragile X Syndrome (FXS)? &#8211; ANSWER- &#8211; Both caused by<br>mutations on the FMR1 gene, but they are caused by different changes in this gene<\/li>\n\n\n\n<li>FXS is caused by a full mutation<\/li>\n\n\n\n<li>FXTAS is a premutation<\/li>\n\n\n\n<li>FXS is present at birth, but display these features in early life<\/li>\n\n\n\n<li>FXTAS develops in adulthood (usually after age 50) and the symptoms may<br>appear slowly and develop over the years<\/li>\n\n\n\n<li>FXTAS individuals are usually healthy with normal cognitive skills prior to the<br>onset<br>How is Fragile X-Associated Tremor\/Ataxia Syndrome (FXTAS) diagnosed? &#8211;<br>ANSWER- &#8211; Being a FMR1 premutation carrier<\/li>\n\n\n\n<li>The appearance of neurological features such as ataxia (balance problems),<br>tremors, and other symptoms<\/li>\n\n\n\n<li>MRI findings (changes in the brain)<br>What is Prader-Willie Syndrome? &#8211; ANSWER- &#8211; Genetic disorder that affects<br>many parts of the body and their growth<\/li>\n\n\n\n<li>Causes mental and behavioral problems<\/li>\n\n\n\n<li>Can be dangerous or life threatening if untreated<\/li>\n\n\n\n<li>Combination of contraceptives contraindicated in breast feeding<\/li>\n\n\n\n<li>More common in females<\/li>\n\n\n\n<li>Confirmed from laboratory findings<\/li>\n<\/ul>\n\n\n\n<p>What is the cause of Prader-Willi Syndrome? &#8211; ANSWER- &#8211; Depletion of<br>chromosome 15 from father<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Missing or non-working genes on chromosome 15 (15q11-q13)<\/li>\n\n\n\n<li>Most cases are not inherited and occur randomly<\/li>\n\n\n\n<li>Depletion of genes (genes from the region are missing)<\/li>\n\n\n\n<li>Uniparental disomy &#8211; both chromosomes are inherited from the mother<\/li>\n\n\n\n<li>Imprinting mutation &#8211; genes on the paternal chromosome is inactive<br>What does Prader-Willi Syndrome do to the body? &#8211; ANSWER- &#8211; Caused the<br>hypothalamus to malfunction (the area of the brain that affects hunger, thirst, sex<br>and growth hormones)<\/li>\n\n\n\n<li>In infancy, an individual does not meet development milestones suck as sitting up<br>and walking<\/li>\n\n\n\n<li>Their eyes lack coordination<br>What is a key feature of Prader-Willi Syndrome? &#8211; ANSWER- &#8211; A constant sense<br>of hunger that usually begins around 2 years of age<\/li>\n\n\n\n<li>People with Prader-Willi Syndrome want to eat constantly because they never<br>feel full<br>What are some symptoms in infants with Prader-Willi Syndrome? &#8211; ANSWER- &#8211;<br>Hypotonia with floppy structure and poor muscle tone<\/li>\n\n\n\n<li>Distinct facial features affecting the shape and size of eyes, lips, forehead, etc.<\/li>\n\n\n\n<li>Poor sucking ability making it difficult to feed<\/li>\n\n\n\n<li>Always lethargic and poor responsiveness<\/li>\n\n\n\n<li>Underdeveloped genitals<br>What is celiac disease? &#8211; ANSWER- &#8211; Autoimmune disease<\/li>\n\n\n\n<li>Damages to the small intestinal epithelium when there is ingestion of gluten<\/li>\n\n\n\n<li>Loss of mucosal surface and brush border enzymes leads to severe malabsorption<br>that is more pronounced in the duodenum and jejunum<br>What strong genetic disposition does celiac disease have? &#8211; ANSWER- &#8211; Human<br>leukocyte antigen DQ2 (HLA-DQ2) and HLA-DQ5<br>What test is recommended for celiac disease? &#8211; ANSWER- &#8211; IgA-tTG<\/li>\n\n\n\n<li>Total IgA<\/li>\n\n\n\n<li>Simple, inexpensive, widely available, typically covered by insurance, and is very<br>accurate in untreated celiac disease<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>WGU D027 OA EXAM 2023-2024 ACTUAL EXAM TEST BANK400 QUESTIONS AND CORRECT DETAILED ANSWERS WITHRATIONALES|AGRADEWhat are some physical changes from Alzheimer&#8217;s dementia? &#8211; ANSWER- &#8211; Brainshrinks dramatically; nerve cell death and tissue loss What medication combination is used to treat moderate-to-severe Alzheimer&#8217;s? &#8211;ANSWER- &#8211; Memantine (namenda) and donepezil (aricept)What is memantine (namenda) used for? &#8211; [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[25],"tags":[],"class_list":["post-112566","post","type-post","status-publish","format-standard","hentry","category-exams-certification"],"_links":{"self":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts\/112566","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/comments?post=112566"}],"version-history":[{"count":0,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts\/112566\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/media?parent=112566"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/categories?post=112566"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/tags?post=112566"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}