ONS\/ONCC Chemotherapy Immunotherapy
Certificate Exam Latest 2023-2024
Questions And Answers (Verified Answers)
Define mutations – ANSWER- Variations in the nucleotide sequence of a gene
3 main goals of treatment: – ANSWER- Cure
Control
Palliation
Define neoadjuvant therapy – ANSWER- Treatment is given prior to surgery to
shrink the tumor
Define adjuvant therapy – ANSWER- Additional cancer treatment given after the
primary treatment to lower the risk that the cancer reoccur
Define conditioning\/preparative therapy – ANSWER- Treatments used to prepare a
patient for stem cell transplantation
2 types of conditioning therapies: – ANSWER- Myeloablative
Nonmyeloablative
Define dose density – ANSWER- Drug dose per unit of time
Define dose intensity – ANSWER- Amount of drug delivered over time
How is relative dose intensity (RDI) calculated? – ANSWER- By comparing the
dose that the patient ACTUALLY received to the planned dose of the standard
regimen
How do alkylating agents work? – ANSWER- By causing a break in the DNA
helix strand, interfering with DNA replication and causing cell death
3 subcategories of alkylating agents: – ANSWER- 1. Nitrogen mustards<\/p>\n\n\n\n
What types of cells are best affected by antimetabolites? – ANSWER- Cells with Lifetime dose of doxorubicin should not exceed: – ANSWER- 550 mg\/m^2 ONS\/ONCC Chemotherapy ImmunotherapyCertificate Exam Latest 2023-2024Questions And Answers (Verified Answers)Define mutations – ANSWER- Variations in the nucleotide sequence of a gene3 main goals of treatment: – ANSWER- CureControlPalliationDefine neoadjuvant therapy – ANSWER- Treatment is given prior to surgery toshrink the tumorDefine adjuvant therapy – ANSWER- Additional cancer treatment given after theprimary treatment to lower the […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[25],"tags":[],"class_list":["post-113710","post","type-post","status-publish","format-standard","hentry","category-exams-certification"],"_links":{"self":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts\/113710","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/comments?post=113710"}],"version-history":[{"count":0,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts\/113710\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/media?parent=113710"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/categories?post=113710"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/tags?post=113710"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
high division rates
Common side effects of antimetabolites: – ANSWER- Myelosuppression
GI toxicities
Photosensitivity
Hand-foot syndrome
Common antimetabolite drugs: – ANSWER- Azacitidine
Capecitabine
5-FU
Cytarabine
Decitabine
Methotrexate
The institute for Safe Medication Practices recommends what route of
administration for vincristine? – ANSWER- IV piggyback via gravity
Anthracycline antitumor abx work by: – ANSWER- Interfering with enzymes
necessary for DNA to replicate in ALL phases of the cell cycle
The two major classifications of antitumor antibiotics are: – ANSWERAnthracyclines
Non-anthracyclines
Common anthracycline antitumor abx: – ANSWER- Daunorubicin
Doxorubicin
Epirubicin
Idarubicin
The antitumor abx _<\/strong><\/em><\/strong> is not an anthracycline, but has anthracyclinetype properties. – ANSWER- Mitoxantrone
Common non-anthracycline antitumor abx: – ANSWER- Actinomycin D
Mitomycin C
Bleomycin
Monitoring necessary with doxorubicin: – ANSWER- Vesicant –> extravasation
Cardiac function
Lifetime dose tracking (cardiotoxicity)<\/p>\n\n\n\n
What cardiac protectant medication can be administered prior to doxorubicin? –
ANSWER- Dexrazoxane
Significant side effects of doxorubicin are: – ANSWER- Cardiotoxicity
N\/V
Mucositis
Diarrhea
Severe myelosuppression
Hepatic impairment
Secondary cancers
Monitoring necessary with bleomycin: – ANSWER- Pulmonary toxicity
Hypersensitivity reactions (esp. in lymphoma patients)
Cutaneous reactions
Lifetime dose tracking (pulmonary toxicity)
Pulmonary fibrosis is possible when the lifetime dose of bleomycin exceeds: –
ANSWER- 400 units
What 6 patient characteristics make CINV more likely? – ANSWER- 1. Younger
than 50 years<\/p>\n\n\n\n\n
Types of CINV: – ANSWER- Acute
Delayed
Breakthrough
Anticipatory
Refractory
Define acute CINV – ANSWER- Occurring within 24 hours of chemotherapy
Define delayed CINV – ANSWER- Occurring from 24 hours to 5 days after
treatment
<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"