{"id":115145,"date":"2023-08-23T12:13:11","date_gmt":"2023-08-23T12:13:11","guid":{"rendered":"https:\/\/learnexams.com\/blog\/?p=115145"},"modified":"2023-08-23T12:13:14","modified_gmt":"2023-08-23T12:13:14","slug":"nurs-5334-nurs5334-advanced-pharmacology-exam-3-study-guide-questions-with-answers","status":"publish","type":"post","link":"https:\/\/www.learnexams.com\/blog\/2023\/08\/23\/nurs-5334-nurs5334-advanced-pharmacology-exam-3-study-guide-questions-with-answers\/","title":{"rendered":"NURS 5334 \/ NURS5334 ADVANCED PHARMACOLOGY EXAM 3 STUDY GUIDE. QUESTIONS WITH ANSWERS."},"content":{"rendered":"\n<p>NURS 5334 EXAM 3<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li>What drugs are used to treat gestational diabetes?<br>Metformin and Insulin<\/li>\n\n\n\n<li>What A1C value indicates diabetes mellitus? Pre-DM?<br>6.5% or greater is considered diabetes<br>5.7-6.4% pre-diabetes<\/li>\n\n\n\n<li>What fasting and random values indicate DM?<br>Fasting plasma glucose\u2014126 or greater is diabetes<br>Random (casual) plasma glucose\u2014anything greater than 200 is diabetes<\/li>\n\n\n\n<li>What are complications of insulin therapy?<br>Hypoglycemia<br>Can develop lipohypertrophy<br>\uf0d8 Accumulation of subcutaneous fat that occurs when it is injected too frequently at<br>the same site<br>Allergic reactions<br>\uf0d8 Characterized by red and intensely itchy welts, breathing becomes difficult<br>\uf0d8 If severe allergy develops:<br>-Desensitization procedure (small doses to larger doses)<br>Hypokalemia<br>\uf0d8 Promotes the uptake of potassium cells and insulin activates a membrane-bound<br>enzyme with sodium potassium and ATPase that pumps potassium into the cells<br>and sodium out<\/li>\n\n\n\n<li>Drug interactions?<br>Hypoglycemic agents<br>\uf0d8 Can intensify the hypoglycemia included by insulin<br>\uf0d8 Examples: sulfonylureas, glinides, alcohol<br>Use with caution with hyperglycemic agents<br>\uf0d8 Examples: thiazide and glucocorticoids and sympathomimetics<\/li>\n\n\n\n<li>What effect do beta blockers have on insulin?<br>\uf0a7 delay awareness of and response to hypoglycemia by masking the signs that are<br>associated with stimulation of sympathetic nervous system<br>\uf0a7 Impair glycogenolysis<br>\uf0a7 Prevent the bodies counter-regulatory response<\/li>\n\n\n\n<li>What are other therapeutic uses besides DM?<br>\uf0a7 Hyperkalemia<br>\uf0a7 Aids in diagnosis of GH deficiency<br>\uf0a7 Diabetic ketoacidosis<\/li>\n\n\n\n<li>Insulin dosage must be coordinated with what?<br>Carbohydrate intake<\/li>\n\n\n\n<li>What is B\/P goal in diabetic?<br>To be controlled, within normal 120\/80<\/li>\n\n\n\n<li>What medication can be given to decrease risk of diabetic nephropathy?<br>ACE inhibitor or ARB<\/li>\n\n\n\n<li>What role does exercise play in treatment of both type 1 and type 2 DM?<br>\uf0d8 Exercise increases cellular responsiveness to insulin and increases glucose<br>tolerance<br>\uf0d8 150 minute per week of moderate intensity exercise is recommended<\/li>\n\n\n\n<li>What are the 4 steps in the 4-step approach?<br>Step 1\u2014diagnosis<br>\uf0a7 Lifestyle changes plus metformin<br>Step 2<br>\uf0a7 Lifestyle changes plus metformin and a second drug (sulfonylurea, TZD or a<br>DPP4 inhibitor, a sodium glucose cotransporter or SGLT-2 inhibitor, a glucagonlike peptide 1, or a GLP-1 receptor agonist or basal insulin<br>\uf0a7 Second drug choice made considering efficacy, the hypoglycemia risk of the<br>patient, the patient tolerability, and weight-related considerations (some help<br>weight loss, some cause weight gain), cost<br>Step 3<br>\uf0a7 Three drug combination<br>\uf0a7 Metformin<br>\uf0a7 Plus 2 other drugs from step 2<br>Decided based on a drug and patient specific considerations<br>Step 4<br>\uf0a7 If 3 drug combination that includes basal insulin fails after 3-6 months, more<br>complex insulin regimen<br>\uf0a7 Usually in combination with one or more non-insulin medications<\/li>\n\n\n\n<li>When a patient is on insulin therapy what are the blood glucose goals before<br>meals? At bedtime?<br>\uf0a7 Before meals\u201470-130<br>\uf0a7 Bedtime\u2014100-140<\/li>\n\n\n\n<li>What is the A1C goal? When is goal below 7 not appropriate?<br>\uf0a7 7% or below<br>\uf0a7 Those with severe hypoglycemia risk, limited life expectancy, advanced micro<br>vascular or macro vascular complications\u2014not below 7<\/li>\n\n\n\n<li>What are the short acting insulins? Intermediate? Long acting?<br>Short duration: Rapid acting<br>\uf0a7 Insulin lispro [Humalog]<br>\uf0a7 Insulin aspart [NovoLog]<br>\uf0a7 Insulin glulisine [Apidra]<br>Short duration: Slower acting<br>\uf0a7 Regular insulin [Humulin R, Novolin R]<br>Intermediate duration<br>\uf0a7 Neutral protamine Hagedorn (NPH) insulin<br>\uf0a7 Insulin detemir [Levemir]<br>Long duration<br>\uf0a7 Insulin glargine<\/li>\n\n\n\n<li>When are short duration insulins used?<br>\uf0a7 Administered in association with meals to control the post-prandial rise in blood<br>glucose between meals and at night<\/li>\n\n\n\n<li>When are intermediate insulins needed?<br>\uf0a7 Administer 2-3 times daily to provide glycemic control between meals and during<br>the night<\/li>\n\n\n\n<li>How long is duration of glargine? Levemir? Degludec?<br>\uf0a7 Glargine\u2014up to 24 hour<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>NURS 5334 EXAM 3<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[25],"tags":[],"class_list":["post-115145","post","type-post","status-publish","format-standard","hentry","category-exams-certification"],"_links":{"self":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts\/115145","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/comments?post=115145"}],"version-history":[{"count":0,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts\/115145\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/media?parent=115145"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/categories?post=115145"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/tags?post=115145"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}