{"id":115388,"date":"2023-08-24T10:47:15","date_gmt":"2023-08-24T10:47:15","guid":{"rendered":"https:\/\/learnexams.com\/blog\/?p=115388"},"modified":"2023-08-24T10:47:16","modified_gmt":"2023-08-24T10:47:16","slug":"wgu-c785-biochemistry-oa-2023-exam-with-100-correct-answer","status":"publish","type":"post","link":"https:\/\/www.learnexams.com\/blog\/2023\/08\/24\/wgu-c785-biochemistry-oa-2023-exam-with-100-correct-answer\/","title":{"rendered":"WGU C785 Biochemistry OA 2023 Exam with 100% Correct Answer"},"content":{"rendered":"\n<p>1 \/ 24<br>WGU C785 Biochemistry OA<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Which level of protein structure is disrupted through the hydrolysis of<br>peptide bonds?<br>Quaternary<br>Tertiary<br>Primary<br>Secondary: Primary<br>The primary structure of a protein is the sequence of amino acids held together by<br>peptide bonds. Peptide bonds are formed by dehydration reactions and disrupted<br>by hydrolysis.<\/li>\n\n\n\n<li>A mutation in the beta-hemoglobin gene, which results in the replacement<br>of the amino acid glutamate in position 6 with the amino acid valine, leads<br>to the development of sickle cell anemia. The structures of glutamate and<br>valine are shown below.<br>If the beta hemoglobin gene in a patient with sickle-cell anemia were to be<br>edited so that the valine in position 6 was replaced with a different amino<br>acid, which replacement for valine would be expected to have the best clinical outcome, in theory, for the patient? (Assume the valine can potentially<br>be replaced with any amino acid other than glutamate.): The original amino<br>acid in a healthy patient is glutamate, which is negatively charged. The mutated<br>amino acid is valine, which is non-polar. Valine is causing sickle cell anemia. The<br>best amino acid to replace valine so that the patient is healthy again would be the<br>one most like glutamate, so any negatively charged amino acid.<\/li>\n\n\n\n<li>Secondary, tertiary, and quaternary levels of protein structure can all be<br>impacted by exposing a protein to which treatment?<br>Change of a hydrophobic amino acid to a different hydrophobic amino acid<br>Addition of a reducing agent<br>Placement of the protein in a solution with a low pH<\/li>\n<\/ol>\n\n\n\n<p>2 \/ 24<br>Increase in the concentration of the protein in solution: Placement of the<\/p>\n\n\n\n<p>3 \/ 24<br>protein in a solution with a low pH<br>Changes in pH affect hydrogen bonds and ionic bonds. Hydrogen bonds in the<br>backbone of amino acids occur in secondary structure, and both hydrogen bonds<br>and ionic bonds occur in the side chains of amino acids in tertiary structure.<\/p>\n\n\n\n<ol class=\"wp-block-list\" start=\"4\">\n<li>An increase in beta-pleated sheet structure in some brain proteins can<br>lead to an increase in amyloid deposit formation, characteristic of some<br>neurodegenerative diseases. What is the primary biochemical process that<br>follows the increase in beta-pleated sheet structure that leads to the development of the amyloid deposits?<br>An increase in glycogen formation in the brain cells<br>Aggregation of the proteins in the brain<br>Secretion of glucagon, leading to excessive ketogenesis<br>An increase in anaerobic metabolism of glucose in the brain: Aggregation of<br>the proteins in the brain<br>This question is describing changes in protein structure. Aggregation occurs when<br>proteins clump together inappropriately, causing plaques like amyloid deposits to<br>accumulate.<\/li>\n\n\n\n<li>Which level of protein structure is determined by the sequence of amino<br>acids?<br>Secondary structure<br>Quaternary structure<br>Tertiary structure<br>Primary structure: Primary structure<br>The primary structure of a protein is simply the sequence of amino acids held<br>together by peptide bonds.<\/li>\n\n\n\n<li>Which force is most influential in determining the secondary structure of<br>a protein?<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>1 \/ 24WGU C785 Biochemistry OA 2 \/ 24Increase in the concentration of the protein in solution: Placement of the 3 \/ 24protein in a solution with a low pHChanges in pH affect hydrogen bonds and ionic bonds. Hydrogen bonds in thebackbone of amino acids occur in secondary structure, and both hydrogen bondsand ionic bonds [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[25],"tags":[],"class_list":["post-115388","post","type-post","status-publish","format-standard","hentry","category-exams-certification"],"_links":{"self":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts\/115388","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/comments?post=115388"}],"version-history":[{"count":0,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts\/115388\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/media?parent=115388"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/categories?post=115388"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/tags?post=115388"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}