{"id":115490,"date":"2023-08-24T11:48:11","date_gmt":"2023-08-24T11:48:11","guid":{"rendered":"https:\/\/learnexams.com\/blog\/?p=115490"},"modified":"2023-08-24T11:48:13","modified_gmt":"2023-08-24T11:48:13","slug":"test-bank-for-essentials-of-medical-genetics-for-nursing-and-health-professionals-1st-edition-mcclary-all-chapters-1-27-full-complete-2023","status":"publish","type":"post","link":"https:\/\/www.learnexams.com\/blog\/2023\/08\/24\/test-bank-for-essentials-of-medical-genetics-for-nursing-and-health-professionals-1st-edition-mcclary-all-chapters-1-27-full-complete-2023\/","title":{"rendered":"Test Bank for Essentials of Medical Genetics for Nursing and Health Professionals 1st Edition McClary \/ All Chapters 1 – 27 \/ Full Complete 2023"},"content":{"rendered":"\n

Essentials of Medical Genetics for Nursing and Health
Professionals 1st Edition McClary Test Bank
Chapter 1 \u2013 Introduction<\/p>\n\n\n\n

    \n
  1. A new patient comes to establish care at the family medicine clinic where you work.
    During your history taking, you create a diagram representing the familial relationships
    among the patient\u2019s relatives to analyze Mendelian inheritance of certain traits. What is
    this diagram called?
    a. Karyotype
    b. Genotype
    c. Pedigree
    d. Genome
    Answer: C
    Rationale: A diagram that represents relationships between family members is called a
    pedigree. Answer A is incorrect because a karyotype is the number and appearance of
    chromosomes within a cell. Answer B is incorrect because a genotype is the genetic
    makeup of a cell. Answer D is incorrect because a genome is the genetic material of an
    organism. Therefore, C is the correct answer choice.<\/li>\n\n\n\n
  2. You are counselling your patient with albinism, which is a homozygous recessive allele.
    She is worried about the chances of her future children being affected by this condition.
    Which of the following isTaEcSorTreBcAt sNtaKteSmEeLntLrEegRa.rdCinOgMyour education of this patient?
    a. More males than females are affected.
    b. Affected individuals would not have affected offspring.
    c. Affected individuals typically have affected parents.
    d. Approximately 50% of siblings with the same parents are affected.
    Answer: B
    Rationale: Answer B is correct because her mating partner is likely homozygous for the
    normal (non-albino) allele, so her offspring would be heterozygous and therefore not
    affected. Answer A is incorrect because this is the description of an X-linked recessive
    condition; males are more affected because they only have one X chromosome and
    therefore require normal functioning of that chromosome. Answer C is incorrect because
    it contradicts the correct answer (B). Answer D is incorrect because all this patient\u2019s
    offspring are likely to be unaffected.<\/li>\n\n\n\n
  3. A karyotype halts mitosis in what stage?
    a. Prophase
    b. Metaphase
    c. Anaphase
    d. Telophase
    Answer: B<\/li>\n<\/ol>\n\n\n\n

    Rationale: During a karyotype, mitosis is stopped in metaphase, just as the chromosomes
    are aligned and most condensed. Answer A is incorrect because the chromosomes are just
    beginning to condense. Answers C and D are incorrect because sister chromatids have
    separated and are being pulled apart. Thus, B is the only correct answer.<\/p>\n\n\n\n

      \n
    1. What genetic test often uses the metaphase arrangement of chromosomes to analyze the
      lengths and positions of their centromeres?
      a. Cytogenetics
      b. Karyotyping
      c. Probing
      d. Fluorescence in situ hybridization (FISH)
      Answer: B
      Rationale: During a karyotype, mitosis is stopped in metaphase, just as the chromosomes
      are aligned and most condensed. Answer A is incorrect because cytogenetics is when
      light microscopy is used to analyze chromosomes. Answer C is incorrect because a probe
      is a small, fluorescent-dyed piece of nucleic acid that is similar to the gene being
      analyzed in fluorescence in situ hybridization (FISH). Answer D is incorrect because
      FISH is a diagnostic technique that uses fluorescence, or light emission, to analyze
      chromosomes with the use of a probe.<\/li>\n\n\n\n
    2. While counselling a coupTDNEpUTHQoQUJMHLrErGJyHg89uy71MyuHRoo.dCthOaMt their child will inherit a certain
      genetic disorder, you explain that some genotypes do not always express their
      corresponding phenotype while other genotypes are always expressed. What concept are
      you explaining?
      a. Cytogenetics
      b. Expressivity
      c. Dominance
      d. Penetrance
      Answer: D
      Rationale: Penetrance is the probability to which a genotype will be phenotypically
      expressed. Traits with full penetrance will be expressed in all patients of that genotype.
      With incomplete penetrance, the disease is not expressed in all patients of that genotype.
      Answer A is incorrect because cytogenetics is using light microscopy to study
      chromosomes. Answer B is incorrect because variable expressivity refers to differences
      in the clinical or phenotypical presentation of a disease. Answer C is incorrect because
      dominance is the ability of a trait to manifest itself in heterozygous carriers. Thus, answer
      D is the correct choice.<\/li>\n\n\n\n
    3. You are a graduate research student studying HIV and need to create large numbers of
      the viral DNA to use in experiments. What process will you use to replicate it
      exponentially?<\/li>\n<\/ol>\n\n\n\n

      a. Polymerase chain reaction
      b. Chromosome painting
      c. Fluorescence in situ hybridization
      d. Karyotyping
      Answer: A
      Rationale: Polymerase chain reaction (PCR) is a technique used to amplify DNA
      exponentially. Answer B is incorrect because chromosome painting is when
      chromosomes are painted difference colors to help identify pairs of homologous
      chromosomes. Answer C is incorrect because fluorescent in situ hybridization (FISH) is a
      diagnostic technique that uses fluorescence, or light emission, to analyze chromosomes
      with the use of a probe. Answer D is incorrect because a karyotype is the number and
      appearance of chromosomes within a cell. Therefore, answer A is the most appropriate
      choice.<\/p>\n\n\n\n

        \n
      1. You suspect your patient has an enzymatic defect. What type of testing is most
        appropriate at this time?
        a. Polymerase chain reaction
        b. Biochemical analysis
        c. Fluorescence in situ hybridization
        d. Karyotyping
        Answer: B
        Rationale: Biochemical analysis is the most appropriate choice because it is used to
        detect the presence of proteins. Answer A is incorrect because Polymerase chain reaction
        (PCR) is a technique used to amplify DNA exponentially. Answer C is incorrect because
        fluorescent in situ hybridization (FISH) is a diagnostic technique that uses fluorescence,
        or light emission, to analyze chromosomes with the use of a probe. Answer D is incorrect
        because a karyotype is the number and appearance of chromosomes within a cell. Thus,
        answer choice B is the best answer.<\/li>\n\n\n\n
      2. A 6-year-old female presents to your pediatrics office with facial tenderness, cough,
        purulent rhinorrhea, and fever. A brief review of her history reveals frequent antibiotic
        use for recurrent lung infections. You recommend biochemical analysis to examine for
        an enzymatic defect in chloride and water transport, also known as:
        a. Phenylketonuria
        b. Primary ciliary dyskinesia
        c. Primary immunodeficiency
        d. Cystic fibrosis
        Answer: D
        Rationale: Biochemical analysis is used for the detection of cystic fibrosis because it is
        used to detect the presence of proteins, namely enzymes. Answer A is incorrect because
        phenylketonuria (PKU) is an absence or deficit in phenylalanine hydroxylase, which<\/li>\n<\/ol>\n\n\n\n

        catabolizes phenylalanine. Answer B is incorrect because primary ciliary dyskinesia is a
        congenital condition where mucus clearance is impaired due to defective or absent cilia.
        Answer C is incorrect because primary immunodeficiency is a susceptibility to diseases
        due to poor antibody production. Thus, answer D is the correct choice.<\/p>\n\n\n\n

          \n
        1. The parents of a newborn baby girl were told that their neonate was screened for inborn
          errors of metabolism this morning. You educate the parents regarding what an inborn
          error of metabolism is and give examples, including phenylketonuria and
          a. Down Syndrome
          b. Cystic fibrosis
          c. Hemophilia
          d. Familial Hypercholesterolemia
          Answer: B
          Rationale: Answer A, answer C, and answer D are not examples of inborn errors of
          metabolism. Only the only choice that is an inborn error of metabolism is cystic fibrosis.
          Therefore, answer B is the best answer.<\/li>\n\n\n\n
        2. A small piece of nucleic acid that is labeled with fluorescent dye used to identify specific
          mutated genes in fluorescence in situ hybridization (FISH) is called a:
          a. Probe
          b. Homolog
          c. Karyotype
          d. Genome
          Answer: A
          Rationale: A probe matches a short part of the DNA being analyzed and is labeled with
          fluorescent dye to help potentially identify mutated genes. Answer B is incorrect because
          homologs are homologous chromosomes that pair up before separating during meiosis.
          Answer C is incorrect because a karyotype is the number and appearance of
          chromosomes within a cell. Answer D is incorrect because a genome is the genetic
          material of an organism. Thus, answer A is the best choice.<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

          Essentials of Medical Genetics for Nursing and HealthProfessionals 1st Edition McClary Test BankChapter 1 \u2013 Introduction Rationale: During a karyotype, mitosis is stopped in metaphase, just as the chromosomesare aligned and most condensed. Answer A is incorrect because the chromosomes are justbeginning to condense. Answers C and D are incorrect because sister chromatids haveseparated and […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[25],"tags":[],"class_list":["post-115490","post","type-post","status-publish","format-standard","hentry","category-exams-certification"],"_links":{"self":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts\/115490","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/comments?post=115490"}],"version-history":[{"count":0,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts\/115490\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/media?parent=115490"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/categories?post=115490"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/tags?post=115490"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}