{"id":115675,"date":"2023-08-24T13:08:13","date_gmt":"2023-08-24T13:08:13","guid":{"rendered":"https:\/\/learnexams.com\/blog\/?p=115675"},"modified":"2023-08-24T13:08:15","modified_gmt":"2023-08-24T13:08:15","slug":"test-bank-for-robbins-and-cotran-pathologic-basis-of-disease-9th-edition-kumar-chapter-2-29-updated-guide-2022","status":"publish","type":"post","link":"https:\/\/www.learnexams.com\/blog\/2023\/08\/24\/test-bank-for-robbins-and-cotran-pathologic-basis-of-disease-9th-edition-kumar-chapter-2-29-updated-guide-2022\/","title":{"rendered":"Test Bank for Robbins and Cotran Pathologic Basis of Disease 9th Edition Kumar | Chapter 2 – 29 | Updated Guide 2022"},"content":{"rendered":"\n

Robbins and Cotran Pathologic Basis of
Disease 9th Edition Kumar Test Bank
Chapter 02: Cellular Responses to Stress and Toxic Insults: Adaptation, Injury, and Death
MULTIPLE CHOICE<\/p>\n\n\n\n

    \n
  1. A 60-year-old man who had generalized atherosclerosis died 24 hours after having a stroke.
    A cerebral infarct was found at autopsy. Necrosis of the brain is classified as
    a. coagulative necrosis
    b. liquefactive necrosis
    c. fat necrosis
    d. fibrinoid necrosis
    e. caseous necrosis
    ANS: B, Brain infarcts are characterized by liquefactive necrosis.<\/li>\n\n\n\n
  2. A 30-year-old woman who had leukemia was treated with bone marrow transplantation. She
    developed a skin rash that was interpreted as a sign of a graft-versus- host reaction. A skin
    biopsy was performed. In the epidermis, there were scattered dead epidermal cells that had
    rounded contours and pyknotic nuclei. This form of cell death is caused by
    a. activation of caspases throTuEgSh TreBceApNtoKrStraEnLsmLiEttRed.sCigOnMals on the cell surface
    b. inhibition of ATPase
    c. inhibition of oxidative phosphorylation
    d. activation of lysosomal enzymes
    e. depletion of glycogen
    ANS: A, Graft-versus-host\u2013induced cell death in the epidermis is a form of apoptosis. It is
    mediated by caspases and other enzymes of the suicide pathway of “programmed cell death.”<\/li>\n\n\n\n
  3. Uptake of bacteria into the cytoplasm of neutrophilic leukocytes is called
    a. autophagocytosis
    b. heterophagocytosis
    c. exocytosis
    d. pinocytosis
    e. involution
    ANS: B, Uptake of bacteria and other exogenous particulate material into the phagosomes is
    called phagocytosis.<\/li>\n\n\n\n
  4. A 90-year-old man died in a nursing home. During the past 10 years, he was unable to care
    for himself and was mentally incoherent. He had no memory and could not hold a
    conversation. He was unaware of his surroundings. At autopsy, the brain showed signs of
    Alzheimer disease, and there were neurons containing numerous neurofibrillary tangles.
    These cytoplasmic structures are formed from which component of the neurons?
    a. Nucleus
    b. Rough endoplasmic reticulum
    c. Smooth endoplasmic reticulum
    d. Mitochondria
    e. Cytoskeleton
    ANS: E, Neurofibrillary tangles are composed of microtubule-associated proteins and
    neurofilaments, which form the cytoskeleton of nerve cells.<\/li>\n\n\n\n
  5. Continuous expression of the gene for atrial natriuretic factor in the myocardial cells of the
    left ventricle is typically a consequence of
    a. myocardial infarction
    b. angina pectoris
    c. hypertension
    d. hypotension
    e. ventricular fibrillation
    ANS: C, Atrial natriuretic factor (ANF) is produced during fetal life in both the atrial and
    ventricular cells of the heart. TAEfteSrTbBirAthN, tKheSAENLLFEgeRn.eCreOmMains active only in the atrium, but
    can be activated in ventricular cells undergoing hypertrophy. Arterial hypertension is the
    most common cause of ventricular hypertrophy.<\/li>\n\n\n\n
  6. Ubiquitin-proteasome degradation of plasma proteins is opposed by
    a. insulin
    b. interleukin-1
    c. tumor necrosis factor \u03b1
    d. glucocorticoids
    e. thyroid hormones
    ANS: A, Insulin can oppose ubiquitin-proteasome degradation of plasma proteins, whereas
    all other hormones and mediators of inflammation listed here accelerate it.<\/li>\n\n\n\n
  7. A 28-year-old man was found to have cirrhosis of the liver and pulmonary emphysema. The
    liver cells contained globular inclusions in their cytoplasm, which by electron microscopy are
    shown to be located inside the
    a. Golgi apparatus
    b. smooth endoplasmic reticulum
    c. rough endoplasmic reticulum
    d. mitochondria
    e. peroxisomes<\/li>\n<\/ol>\n\n\n\n

    1-3
    ANS: C, The clinical history (i.e., the concurrence of cirrhosis and pulmonary emphysema)
    suggests that this young man has \uf0611-antitrypsin (AAT) deficiency. The cytoplasmic globules
    in the liver cells represent misfolded AAT, which cannot be excreted from the liver cells and
    remains inside the liver cells in the dilated cisterns of the rough endoplasmic reticulum.<\/p>\n\n\n\n

      \n
    1. A 60-year-old obese man was admitted to the hospital for treatment of alcoholism. He has
      diabetes mellitus. A liver biopsy was performed, and the specimen showed that the liver cells
      contain increased amounts of
      a. hemosiderin
      b. bile
      c. triglycerides
      d. bilirubin
      e. insulin
      ANS: C, The three most common causes of fatty liver are obesity, alcoholism, and diabetes
      mellitus. Fat is stored in the liver cells predominantly in the form of triglycerides.<\/li>\n\n\n\n
    2. A 55-year-old man who was on renal dialysis was admitted to the hospital for evaluation of
      nausea and vomiting. A gastric biopsy was performed. The gastric mucosa contained foci of
      amorphous, bluish (basophilic) material forming aggregates 10-20 \uf06dm in diameter. These
      aggregates were seen mostly in the stroma between the foveolar cells. No other abnormalities
      were seen, and the pathologist concluded that these changes represent evidence of
      a. Helicobacter pylori infection
      b. peptic ulcer formation
      c. dystrophic calcification
      d. metastatic calcification
      e. apoptosis
      ANS: D, Bluish material in the stroma of the stomach represents foci of calcification. In
      patients who have chronic renal disease, such calcifications occur in the stomach, the lungs,
      or the kidneys, and are classified as metastatic. Metastatic calcifications occur in patients
      who have hypercalcemia, which in this patient was most likely caused by secondary
      hyperparathyroidism.<\/li>\n<\/ol>\n\n\n\n

      Kumar: Robbins and Cotran Pathologic Basis of Disease, 9th Edition
      Chapter 03: Inflammation and Repair
      Test Bank
      MULTIPLE CHOICE<\/p>\n\n\n\n

        \n
      1. Transmembrane adhesive heterodimeric proteins, composed of an \uf061 and a \u00df chain, are
        expressed on activated leukocytes during inflammation. They bind primarily to intercellular
        adhesion molecule 1 (ICAM-1) and vascular cell adhesion molecule 1 (VCAM-1), both of
        which belong to the family of proteins known as
        a. selectins
        b. integrins
        c. immunoglobulins
        d. lectins
        e. growth factors
        ANS: C, Surface proteins expressed on activated leukocytes are integrins, and they bind to
        intercellular adhesion molecule 1 (ICAM-1) and vascular cell adhesion molecule 1 (VCAM1), which belong to the immunoglobulin family of proteins.<\/li>\n\n\n\n
      2. Which of the following mTedEiaStoTrBs AoNf KinSfElaLmLmEatRio.nCOhaMs chemotactic properties and is
        increased in persons taking aspirin?
        a. Thromboxane A2
        b. Prostaglandin E2
        c. Platelet-activating factor
        d. Leukotriene B4
        e. Interleukin-1
        ANS: D, Leukotriene B4 is chemotactic. It is increased in persons who take aspirin, because
        aspirin inhibits the cyclooxygenase pathway, thus shunting more arachidonic acid early
        derivatives into the lipoxygenase pathway. This promotes the synthesis of leukotrienes.<\/li>\n\n\n\n
      3. A 2-year-old child known to suffer from recurrent bacterial infections and poor wound
        healing was found to have leukocyte adhesion molecule deficiency 1 (LAD-1). The
        leukocytes of this patient do not express CD18, a molecule classified as belonging to the
        family of
        a. selectins
        b. integrins
        c. lectin type of vascular adhesion molecules
        d. aminotransferases
        e. glycosidases<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

        Robbins and Cotran Pathologic Basis ofDisease 9th Edition Kumar Test BankChapter 02: Cellular Responses to Stress and Toxic Insults: Adaptation, Injury, and DeathMULTIPLE CHOICE 1-3ANS: C, The clinical history (i.e., the concurrence of cirrhosis and pulmonary emphysema)suggests that this young man has \uf0611-antitrypsin (AAT) deficiency. The cytoplasmic globulesin the liver cells represent misfolded AAT, which […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[25],"tags":[],"class_list":["post-115675","post","type-post","status-publish","format-standard","hentry","category-exams-certification"],"_links":{"self":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts\/115675","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/comments?post=115675"}],"version-history":[{"count":0,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts\/115675\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/media?parent=115675"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/categories?post=115675"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/tags?post=115675"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}