{"id":117574,"date":"2023-08-29T08:26:41","date_gmt":"2023-08-29T08:26:41","guid":{"rendered":"https:\/\/learnexams.com\/blog\/?p=117574"},"modified":"2023-08-29T08:26:44","modified_gmt":"2023-08-29T08:26:44","slug":"mls-hematology-complete-package-dealguaranteed-success","status":"publish","type":"post","link":"https:\/\/www.learnexams.com\/blog\/2023\/08\/29\/mls-hematology-complete-package-dealguaranteed-success\/","title":{"rendered":"MLS HEMATOLOGY COMPLETE PACKAGE DEAL|GUARANTEED SUCCESS"},"content":{"rendered":"\n

MLS Review Hematology
(Hct \/ RBC) * 10 – correct answer MCV calculation
(Hgb \/ Hct) * 100 – correct answer MCHC calculation
reticulocytes(%) * (Hct \/ 45) – correct answer corrected reticulocyte calculation
acid, eosin, pink – correct answer when the pH is too low (<6.4), the red cells take up more dye, (<\/em><\/strong><\/em><\/strong>) becoming more _ heinz bodies – correct answer which RBC inclusion does not show up with Wrights stain MCH – correct answer which RBC indice is not affected by Hct? MCHC in excess of 36% – correct answer spherocytosis is most associated with what RBC indice coefficient of variaition – correct answer statistical term which is a good index of precision right – correct answer acidosis is a shift to the __<\/em><\/strong>
alkalosis – correct answer a shift to the left is acidosis or alkalosis?
lymphocytes – correct answer aplastic anemia shows elevation of what leukocyte
20-44% – correct answer normal percentage of adult leukocytes
1-8% – correct answer normal monocyte percentage<\/p>\n\n\n\n

polychromatic normoblast – correct answer first stage of RBC maturation when
cytoplasm is pink from hemoglobin
beta4 – correct answer hemoglobin configuration characteristic of Hgb H
leukopenia – correct answer hypersplenism is characterized by:
spleen – correct answer organ responsible for pitting process of RBCs
normocytic, normochromic – correct answer classification of anemia in sickle cell
disease
Hgb A (50-70%) (Hgb S =20-40%) – correct answer major Hgb found in people with sickle
cell trait
valine for glutamic acid – correct answer amino acid substitution responsible for sickle
cell anemia
sickle cell disease – correct answer condition where autosplenectomy may occur
Anti-P – correct answer antibody associated with paroxysmal cold hemoglobinuria
G6PD deficiency – correct answer bite cells are usually seen in patients with:
spherocytic red cells – correct answer autoimmune hemolytic anemia characterized by
RBC indices – correct answer morphological classification of anemia is based on
bizzare multinucleated erythroblasts – correct answer congenital dyserythropoetic
anemias (CDAs) are characterized by:<\/p>\n\n\n\n

ASCP MLS Hematology
Insufficient centrifugation will result in:
A. A false increase in hematocrit (Hct) value
B. A false decrease in Hct value
C. No effect on Hct value
D. All of these options, depending on the patient – correct answer A. Insufficient
centrifugation does not pack down the
red blood cells; therefore, the Hct, which is the
volume of packed cells, will increase.
Variation in red cell size observed on the peripheral smear is described as:
A. Anisocytosis
B. Hypochromia
C. Poikilocytosis
D. Pleocytosis – correct answer A. A mature erythrocyte is approximately 7-8 \u03bcm in
diameter. Variation in normal size is denoted by the
term anisocytosis. Hypochromia is a term that indicates increased central pallor in
erythrocytes, and poikilocytosis denotes variation in red cell shape.
Which of the following is the preferable site for bone marrow aspiration and biopsy in an
adult?
A. Iliac crest
B. Sternum
C. Tibia
D. Spinous processes of a vertebra – correct answer A. The iliac crest is the most
frequently used site for
bone marrow aspiration and biopsy. This site is the<\/p>\n\n\n\n

safest and most easily accessible, with the bone just
beneath the skin, and neither blood vessels nor
nerves are in the vicinity.
Mean cell volume (MCV) is calculated using the following formula:
A. (Hgb \/ RBC) \u00d7 10
B. (Hct \/ RBC) \u00d7 10
C. (Hct \/ Hgb) \u00d7 100
D. (Hgb \/ RBC) \u00d7 100 – correct answer B. MCV is the average “volume” of the red cells.
This is
obtained by dividing the Hct or packed cell volume
(PCV) by the red blood cell (RBC) count in millions per
microliter of blood and multiplying by 10. The MCV is
expressed in cubic microns (\u03bcm3) or femtoliters (fL).
What term describes the change in shape of erythrocytes seen on a Wright’s-stained
peripheral blood smear?
A. Poikilocytosis
B. Anisocytosis
C. Hypochromia
D. Polychromasia – correct answer A. Variation in shape of the erythrocytes on a
peripheral
blood smear is poikilocytosis. Anisocytosis refers to a
change in size. Hypochromia is an increase in central
pallor in erythrocytes. Polychromasia describes the bluish tinge of the immature
erythrocytes (reticulocytes) circulating in the peripheral blood.
Calculate the mean cell hemoglobin concentration (MCHC) using the following values:<\/p>\n\n\n\n

Hgb: 15 g\/dL (150 g\/L)
Hct: 47 mL\/dL (0.47)
RBC: 4.50 \u00d7 106\/\u03bcL (4.50 \u00d7 1012\/L)
A. 9.5% (.095)
B. 10.4% (.104)
C. 31.9% (.319)
D. 33.3% (.333) – correct answer C. MCHC is the average concentration of Hgb in red
cells expressed as a percentage. It expresses the ratio of the weight of Hgb to the volume
of erythrocytes and is calculated by dividing Hgb by the Hct, and then multiplying by 100.
A decreased MCHC indicates that cells are hypochromic. In this example, (15 \u00f7 47) \u00d7 100
= 31.9%. The reference range for MCHC is 32%-36%.
A manual white blood cell (WBC) count was performed. A total of 36 cells were counted
in all 9-mm^2 squares of a Neubauer-ruled hemacytometer. A 1:10 dilution was used.
What is the WBC count?
A. 0.4 \u00d7 10^9\/L
B. 2.5 \u00d7 10^9\/L
C. 4.0 \u00d7 10^9\/L
D. 8.0 \u00d7 10^9\/L – correct answer A. The formula used for calculating manual cell counts
using a hemacytometer is:
Number of cells counted \u00d7 dilution factor \u00d7 depth factor (10) divided by the area.
In this example, 36 \u00d7 10 \u00d7 10 = 3600 \u00f7 9 = 400\/mm^3 or 0.4 \u00d7 10^9\/L.
When an erythrocyte containing iron granules is stained with Prussian blue, the cell is
called a:
A. Spherocyte
B. Leptocyte<\/p>\n\n\n\n

C. Schistocyte
D. Siderocyte – correct answer D. Siderocytes are red cells containing iron granules
and are visible when stained with Prussian blue.
A 7.0-mL ethylenediaminetetraacetic acid (EDTA) tube is received in the laboratory
containing only 2.0 mL of blood. If the laboratory is using manual techniques, which of
the following tests will most likely be erroneous?
A. RBC count
B. Hemoglobin (Hgb)
C. Hct
D. WBC count – correct answer C. Excessive anticoagulant causes shrinkage of cells;
thus, the Hct will be affected. RBC and WBC counts
remain the same, as does the Hgb content.
A 1:200 dilution of a patient’s sample was made and 336 red cells were counted in an
area of 0.2 mm^2. What is the RBC count?
A. 1.68 \u00d7 1012\/L
B. 3.36 \u00d7 1012\/L
C. 4.47 \u00d7 1012\/L
D. 6.66 \u00d7 1012\/L – correct answer B. RBC count = number of cells counted \u00d7 dilution
factor \u00d7 depth factor (10), divided by the area.
In this example, 336 \u00d7 200 \u00d7 10 = 672,000 \u00f7 0.2 = 3.36 \u00d7
106\/mm^3 = 3.36 \u00d7 10^12\/L.
What phagocytic cells produce lysozymes that are bacteriocidal?
A. Eosinophils
B. Lymphocytes
C. Platelets<\/p>\n\n\n\n

MLS Hematology Hematology
Hematopoiesis – correct answer Production and development of blood cells normally
occurring in the bone marrow
Yolk sac – correct answer -the beginning of hematopoiesis
-begins as early as the eighteenth day after fertilization
Aorta-gonad-mesonephros (AGM) – correct answer -the beginning of intraembryonic
hematopoiesis
-beings at about four weeks of gestation
Where is the location of hematopoiesis during the fetal development at the third month? –
correct answer liver
Bone Marrow – correct answer -the blood-forming tissue located between the trabeculae
of spongy bone
-location for formation and maturation of blood cells
Two major departments of the bone marrow – correct answer -vascular compartment
-endosteal compartment
Vascular Compartment – correct answer composed of the bone marrow arteries and
veins, stromal cells, and hematopoietic cells
Endosteal Compartment – correct answer the primary site of bone remodeling but also
contains hematopoietic stem cells (HSCs)
Bone Marrow Hyperplasia – correct answer -an excessive proliferation of normal cells
-occurs with all conditions of increased of ineffective hematopoiesis<\/p>\n\n\n\n

Extramedullary hematopoiesis – correct answer the formation and development of blood
cells at a site other than the bone marrow
Bone marrow is the site of cell development for __<\/strong><\/em><\/strong>. – correct answer -myeloid
cells
-erythroid cells
-megakaryocytic cells (mother cells)
-lymphoid cells
What are other sites of cell development for lymphoid cells besides the bone marrow? –
correct answer -thymus
-spleen
-lymph nodes
Bone Marrow Hypoplasia – correct answer -hematopoietic tissue becomes inactive
-fat cells increase to offer a cushion for the marrow
What are some causes for bone marrow hypoplasia? – correct answer Environmental
factors
-chemicals
-toxins
Genetically determined
Blood Cell Passage – correct answer blood cells migrate from bone marrow to the
vascular space
What causes extramedullary hematopoiesis? – correct answer hyperplasia of the marrow
does not meet the physiologic needs of the tissues
Where does extramedullary hematopoiesis usually occur? – correct answer -liver
-spleen<\/p>\n\n\n\n

Thymus – correct answer lymphopoietic organ
-bilobular organ with an outer cortex and central medulla
-supplies immunocompetent T lymphocytes to T-dependent areas
What is inside the cortex of the thymus? – correct answer -small lymphocytes
(thymocytes)
-cortical epithelial cells
-few macrophages
What is inside the medulla of the thymus? – correct answer -mature thymocytes
-medullary epithelial cells
-dendritic cells
-macrophages
Hypersplenism – correct answer spleen may become enlarged
-happens through the exaggeration of its normal activities of filtering and phagocytosis
What does hypersplenism cause? – correct answer -anemia
-leukopenia (decreased WBC)
-thrombocytopenia (decreased platelets)
-combinations of cytopenias (decreased cells)
Splenectomy – correct answer removal of the spleen
Splenectomy’s effect of the lifespan of RBCs – correct answer stays the same
Kupffer cells – correct answer -special macrophages that line the sinusoids
-performs similar filtering functions as the phagocytes in the splenic cords and marginal
zones<\/p>\n\n\n\n

MLS Hematology Hematology
Hematopoiesis – correct answer Production and development of blood cells normally
occurring in the bone marrow
Yolk sac – correct answer -the beginning of hematopoiesis
-begins as early as the eighteenth day after fertilization
Aorta-gonad-mesonephros (AGM) – correct answer -the beginning of intraembryonic
hematopoiesis
-beings at about four weeks of gestation
Where is the location of hematopoiesis during the fetal development at the third month? –
correct answer liver
Bone Marrow – correct answer -the blood-forming tissue located between the trabeculae
of spongy bone
-location for formation and maturation of blood cells
Two major departments of the bone marrow – correct answer -vascular compartment
-endosteal compartment
Vascular Compartment – correct answer composed of the bone marrow arteries and
veins, stromal cells, and hematopoietic cells
Endosteal Compartment – correct answer the primary site of bone remodeling but also
contains hematopoietic stem cells (HSCs)
Bone Marrow Hyperplasia – correct answer -an excessive proliferation of normal cells
-occurs with all conditions of increased of ineffective hematopoiesis<\/p>\n\n\n\n

Extramedullary hematopoiesis – correct answer the formation and development of blood
cells at a site other than the bone marrow
Bone marrow is the site of cell development for __<\/strong><\/em><\/strong>. – correct answer -myeloid
cells
-erythroid cells
-megakaryocytic cells (mother cells)
-lymphoid cells
What are other sites of cell development for lymphoid cells besides the bone marrow? –
correct answer -thymus
-spleen
-lymph nodes
Bone Marrow Hypoplasia – correct answer -hematopoietic tissue becomes inactive
-fat cells increase to offer a cushion for the marrow
What are some causes for bone marrow hypoplasia? – correct answer Environmental
factors
-chemicals
-toxins
Genetically determined
Blood Cell Passage – correct answer blood cells migrate from bone marrow to the
vascular space
What causes extramedullary hematopoiesis? – correct answer hyperplasia of the marrow
does not meet the physiologic needs of the tissues
Where does extramedullary hematopoiesis usually occur? – correct answer -liver
-spleen<\/p>\n\n\n\n

Thymus – correct answer lymphopoietic organ
-bilobular organ with an outer cortex and central medulla
-supplies immunocompetent T lymphocytes to T-dependent areas
What is inside the cortex of the thymus? – correct answer -small lymphocytes
(thymocytes)
-cortical epithelial cells
-few macrophages
What is inside the medulla of the thymus? – correct answer -mature thymocytes
-medullary epithelial cells
-dendritic cells
-macrophages
Hypersplenism – correct answer spleen may become enlarged
-happens through the exaggeration of its normal activities of filtering and phagocytosis
What does hypersplenism cause? – correct answer -anemia
-leukopenia (decreased WBC)
-thrombocytopenia (decreased platelets)
-combinations of cytopenias (decreased cells)
Splenectomy – correct answer removal of the spleen
Splenectomy’s effect of the lifespan of RBCs – correct answer stays the same
Kupffer cells – correct answer -special macrophages that line the sinusoids
-performs similar filtering functions as the phagocytes in the splenic cords and marginal
zones<\/p>\n\n\n\n

MLS Hematology Final
Which is true regarding the red blood cell? – correctanswer The body increases the
amount of RBC progenitors at all times to increase the response time when anemia
occurs.
Active hematopoiesis in an adult would most likely take place in the: – correctanswer Hip
What are the two reasons that the erythrocyte loses its nucleus?(multiple) –
correctanswer To gain membrane deformability; To allow for better oxygen transport into
the tissues
What is the major function of the erythrocyte? – correctanswer Oxygen transport
Which descibe intravascular hemolysis?(multiple) – correctanswer It can result from
membrane damage caused by the turbulence in the chambers of the heart; It can be
triggered by membrane-bound complement proteins
Why do newborns have a higher normal red cell count than adults? – correctanswer The
newborns cells have a higher concentration of Hgb F which has a higher affinity for
oxygen
As the erythrocyte matures, why does it decrease in size? – correctanswer It undergoes
multiple cell divisions
Which term describes hematopoiesis that takes place outside the bone marrow? –
correctanswer Extramedullary
Match the organ: Liver – correctanswer Can be site of hematopoiesis during bone marrow
failure
Match the organ: Kidney – correctanswer involved in the detection of hypoxia in
erythrocytes<\/p>\n\n\n\n

Match the organ: Thymus – correctanswer the site for T cell maturation
Match the organ: Spleen – correctanswer Involved in the removal of damaged or
senescent red blood cells
Match the organ: Lymph nodes – correctanswer Site of antigenic encounter for specific B
cells and T cells
Match the organ: Bone Marrow – correctanswer The major site for hematopoiesis in an
adult
A cardiac patient would be expected to have a lower number of red cells in circulation
due to his physiological condition. – correctanswer False
As the erythrocyte matures, why does the cytoplasm change from blue to pink?
(multiple) – correctanswer Blue-staining RNA synthesis decreases; Pink-staining
hemoglobin synthesis increases
The number of RBCs in circulation is controlled by a variety of factors. Which would NOT
be considered a normal control mechanism? – correctanswer Necrosis
Which defines the last mitotic stage of erythropoiesis? – correctanswer Polychromatic
normoblast
A stem cell committed to becoming a B cell will have which CD marker? – correctanswer
CD19
Which best defines a stem cell? (multiple) – correctanswer Is subject to apoptosis if the
numbers are too high; can give rise to an identical daughter cell without differentiation;
has the ability to differentiate into all functional cell types
Match the cell type: Endothelial cells – correctanswer Help regulate the passage of
particles entering and leaving the hematopoietic spaces<\/p>\n\n\n\n

Match the cell type: Macrophages: – correctanswer Store recycled iron
Match the cell type: Stromal cells – correctanswer Originate from the mesenchymal cells
Match the cell type: Mesenchymal cells – correctanswer A type of embryonic tissue that
migrates into the marrow to support blood cell development
Match the cell type: Adipocytes – correctanswer Help regulate the volume of the bone
marrow
Match the cell type: Reticular adventitial cells – correctanswer Extend fibers into the bone
marrow cavity on which mature blood cells will adhere
Erythropoietin has a positive influence on erythropoiesis. Which would be considered a
mechanism of action by the hormone? (multiple) – correctanswer It inhibits the
production of adhesion molecule receptors on the maturing red blood cell; It stimulates
RNA synthesis of the red blood cells; It inhibits normal apoptosis; It causes an increase
in the release of reticulocytes form the bone marrow
What ultimately happens to the nucleus of the mature erythrocyte? – correctanswer It is
extruded from the cell in a membrane-bound vesicle and is phagocytized by
macrophages
During hematopoiesis, which cell type, located toward the middle of the extravascular
cord in the bone marrow, undergoes receptor-mediated migration toward the periphery of
the cord as they mature? – correctanswer Granulocytes
Match the events: This phase begins around the fourth month gestation – correctanswer
Medullary
Match the events: The 3:1 ratio of myeloid to erythroid cells is achieved in this phase –
correctanswer Medullary
Match the events: Cell development occurs inside the developing blood vessels –
correctanswer Mesoblastic<\/p>\n\n\n\n

Hematology Exam 1 MLS
Protoporphyrin ring is the backbone of what? – correct answer Heme Molecule
Protoporphyrin combines with what to make Heme? – correct answer Fe++ or Ferrous
Iron
Hemoglobin and Ferric Iron = – correct answer Methemoglobin
Hemoglobin + CO2 = – correct answer Carbaminohemoglobin
1 g Hbg contains how much O2 – correct answer 1.34 mL O2
1g Hgb contains how much iron? – correct answer 3.47 mg Fe
Drabkin’s reagent is used in what method of hemoglobin measurement? – correct answer
Cyanmethemoglobin
This reagent contains
-NaHCO3
-KCN
-K3FeCN
-Water – correct answer Drabkin’s reagent
What wavelength is cyanmethemoglobin measured? – correct answer 540 nm
Potassium ferricyanide oxidizes Hb to methemoglobin, then potassium cyanide converts
MetHgB to Cyanmethemoglobin.
Why would this be a useful chemical reaction for measuring hemoglobin concentrations?<\/p>\n\n\n\n