2021 Family Nurse Practitioner FNP
Pharmacology Exam Cram
Tetracycline: may cause permanent discoloration of teeth, if taken during
the last half of pregnancy, in infancy, or by children less than 8 years of
age. – Doxycycline PO BID first line chlamydial and atypical bacterial
infection
Minocycline has more side effects and adverse effects (vertigo and
dizziness)
tetracycline first -line moderate to severe acne, rosacea
Tetracycline: adverse effect – Photosensitivity, Esophageal ulceration
Mild acne – use topical benzamycin, Retin-A
Tetracycline first -line for moderate to severe acne, rosacea – if not better
after 2-3 month of topical benzamycin, Retin-A use
Tetracycline may decrease effectiveness of – oral contraceptive
Macrolides (preg cat B) – Erythromycin (cat B) clarithromycin (cat c) , both
are potent CYP 34A inhibitor high drug interaction
Azithromycin (Cat B) fewer drug interaction
Macrolides: side effects – GI distress especially with erythromycin so switch
to azithromycin
ototoxicity, cholestatic jaundice, QT prolongation<\/p>\n\n\n\n
Cephalosporins first generation (G+ve)
cephalexin (Keflex) PO QID – Pregnancy: UTI (if sensitive)
skin: impetigo, cellulitis, Mastitis
Cephalosporins Second generation (G -ve\/G+ve)
Cefuroxime axetil (ceftin) PO BID
Cefprozil (cefzil) PO BID
Cefaclor (Ceclor)PO BID – Indication:
ENT: sinusitis, Otitis media
Respiratory: CAP, exacerbation chronic bronchitis
Other: AOM, Sinusitis, Skin infection
Cephalosporins Third generation (G-ve)
Cefriaxone (Rocephin) IM
Cefixime (Suprax) daily to BID
Cefdinir (Omnicef) daily to BID – Indication:
STD: Gonorrhea cervicitis, Urethritis, PID
ENT: AOM in children, acute sinusitis, otitis media
GU: Pyelonephritis, CAP
Penicilline V Po QID – Strep throat first line
Amoxicilline BID to TID – Otitis media first line<\/p>\n","protected":false},"excerpt":{"rendered":"
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