{"id":118521,"date":"2023-09-04T23:01:57","date_gmt":"2023-09-04T23:01:57","guid":{"rendered":"https:\/\/learnexams.com\/blog\/?p=118521"},"modified":"2023-09-04T23:02:03","modified_gmt":"2023-09-04T23:02:03","slug":"ancc-domain-1-scientific-foundation-40-questions-with-rationales","status":"publish","type":"post","link":"https:\/\/www.learnexams.com\/blog\/2023\/09\/04\/ancc-domain-1-scientific-foundation-40-questions-with-rationales\/","title":{"rendered":"ANCC Domain 1: Scientific Foundation (40 questions with rationales)"},"content":{"rendered":"\n<p>As a PMHNP, you are aware of antipsychotic medication side effects. Which of<br>the following side effects of antipsychotic medications has an insidious,<br>delayed-onset typically 1 to 2 years after initiation of the medication?<br>a. Dry mouth<br>b. Tardive dyskinesia<br>c. Sedation<br>d. Weight gain &#8211; B<br>In evaluating a 4-year-old, one would expect which of the following delays in<br>Asperger&#8217;s Disorder?<br>a. Language development<br>b. Cognitive development<br>c. Motor skills coordination<br>d. Social skills development &#8211; D<br>Which area of the brain has been implicated to modulate pain and can help<br>explain how transcranial magnetic stimulation can help decrease pain?<br>a. Prefrontal cortex<br>b. Insula cortex<br>c. Dorsolateral prefrontal cortex<br>d. Anterior cingulate cortex &#8211; A<br>Which of the following antidepressants is associated with dose-related<br>cardiovascular adverse effects which require adherence to maximum<br>recommended dosing, unless higher doses are deemed appropriate despite<br>risks?<br>a. Citalopram (Celexa)<br>b. Venlafaxine (Effexor)<br>c. Mirtazapine (Remeron)<br>d. Sertraline (Zoloft) &#8211; A<br>Which of the following findings would raise concern in an annual sports exam<br>for a 15-year-old girl?<br>a. Scar tissue from hymenal tear at 11 o&#8217;clock (reported biking injury)<br>b. Blood pressure 86\/56<br>c. Height 67 inches, weight 102 pounds<br>d. Pulse 60, respirations 26 &#8211; C<\/p>\n\n\n\n<p>A week after raising the dose of risperidone (Risperdal), a patient treated for<br>schizophrenia presents to the clinic with reports of an acute change in mental<br>status, fever, and rigidity. As the treating PMHNP, you know these symptoms<br>are consistent with which of the following?<br>a. Neuroleptic malignant syndrome (NMS)<br>b. Anticholinergic withdrawal syndrome<br>c. Extrapyramidal side effects<br>d. Serotonin syndrome &#8211; A<br>Which of the following statements regarding disulfiram (Antabuse is correct?<br>a. Disulfiram should not be taken for at least 6 hours after drinking alcohol.<br>b. Avoid anything containing alcohol (i.e., vinegar, mouthwash, aftershave,<br>cough medication) while using disulfiram and for 2 weeks after discontinuing.<br>c. A disulfiram-alcohol reaction can occur up to 1 week after discontinuing<br>disulfiram.<br>d. Disulfiram can lower liver function tests so monitoring is necessary. &#8211; B<br>Which mood stabilizer is most associated with a potentially life-threatening<br>rash?<br>a. Divalproex (Depakote)<br>b. Lamotrigine (Lamictal)<br>c. Lithium (Eskalith)<br>d. Carbamazepine (Tegretol) &#8211; B<br>Which of the following statements most accurately reflects the predominant<br>risk factors of antisocial personality disorders?<br>a. Gang affiliation and early substance abuse<br>b. Genetic predisposition of first-degree family member<br>c. Childhood abuse and trauma from domestic violence<br>d. Lower socioeconomic status from single-parent families &#8211; B<br>A 37-year-old patient with schizophrenia is started on a high dose of<br>chlorpromazine (Thorazine). The next day, he complains of lightheadedness<br>after standing up. Vital sign changes reflect a significant decrease in blood<br>pressure and an increase in heart rate. You suspect this is secondary to the<br>alpha 1-adrenergic blockade which is causing<br>a. Orthostatic hypotension<br>b. Dry mouth<\/p>\n\n\n\n<p>c. Respiratory depression<br>d. Decreased sweating &#8211; A<br>A 74-year-old female presents for an evaluation. The psychiatric nurse<br>practitioner has the patient complete the mini mental status examination and<br>clock drawing. The patient is unable to correctly draw the face of the clock.<br>Which area of the brain is likely to have a compromised functioning?<br>a. Wernicke&#8217;s Area<br>b. Corpus Callosum<br>c. Left Hemisphere<br>d. Right hemisphere &#8211; D<br>Your patient comes into the office for her middle of the year appointment. She<br>is diagnosed with Bipolar I disorder. She has been maintained well for the past<br>3 years on Oxcarbazepine (Trileptal) 900 mg po QHS. Her labs are normal<br>except for a blood sugar of 114 and her hemoglobin A1C is 5.6. She has a<br>normal energy level and states that her mood is stable but complains of<br>excessive urination and thirst. You suspect:<br>a. Possible Diabetes 2<br>b. Possible hyponatremia<br>c. Possible polydipsia<br>d. Side effects of oxcarbazepine &#8211; D<br>What is a rare but serious side effect of trazodone (Desyrel)?<br>a. Confusion<br>b. Priapism<br>c. Rash<br>d. Tremor &#8211; B<br>When studying pharmacodynamics involving receptors, you know that an<br>inverse agonist produces the following effect:<br>a. Does not fully activate the receptor and causes only limited actions<br>b. Causes the opposite effect of agonist, and causes the receptor to close the<br>ion channel<br>c. Blocks the agonist from opening the channel, and does not activate a<br>biological response<br>d. Activates a biological response, and opens the ion channel. &#8211; B<\/p>\n\n\n\n<p>Mr. Smith is a 56-year-old white male who has been successfully treated on<br>Selegiline for over 4 years. Mr. Smith is going in for an elective surgical<br>procedure. Which medication is strictly contraindicated with Selegiline?<br>a. Non-steroidal anti-inflammatory drugs (NSAIDs)<br>b. Meperidine<br>c. Codeine<br>d. Morphine &#8211; B<br>Patty is a 62-year-old white female with Bipolar I Disorder and has been<br>stable for 2 years on valproate and risperidone. She was recently diagnosed<br>with shingles, and her primary care nurse practitioner started her on<br>corticosteroids. As the PMHNP treating Patty, you are concerned that the<br>addition of the corticosteroids may cause<br>a. Neuroleptic Malignant Syndrome<br>b. A hypertensive crisis<br>c. A manic episode<br>d. Stevens-Johnson syndrome &#8211; C<br>Which serotonin receptor antagonism makes an antipsychotic &#8220;atypical&#8221;?<br>a. 5HT4A<br>b. 5HT1A<br>c. 5HT3A<br>d. 5HT2A &#8211; D<br>What direct-acting dopamine receptor agonist is recommended to be used in<br>the treatment of neuroleptic malignant syndrome (NMS) to help lower the<br>dopamine receptor blockade?<br>a. Benztropine (Cogentin)<br>b. Bromocriptine (Parlodel)<br>c. Trihexyphenidyl (Artane)<br>d. Dantrolene (Dantrium) &#8211; B<br>A 17-year-old female presents to your clinic reporting anhedonia, decreased<br>energy, and hopelessness for the past two years. She denies drinking alcohol,<br>smoking, or using illegal substances. Her physical examination results are<br>within normal limits and she denies suicidal ideations. As the treating<br>psychiatric mental health nurse practitioner, you decide to prescribe her<br>bupropion (Wellbutrin). Of the following, which is contraindication for the use<br>of bupropion?<\/p>\n","protected":false},"excerpt":{"rendered":"<p>As a PMHNP, you are aware of antipsychotic medication side effects. Which ofthe following side effects of antipsychotic medications has an insidious,delayed-onset typically 1 to 2 years after initiation of the medication?a. Dry mouthb. Tardive dyskinesiac. Sedationd. Weight gain &#8211; BIn evaluating a 4-year-old, one would expect which of the following delays inAsperger&#8217;s Disorder?a. Language [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[25],"tags":[],"class_list":["post-118521","post","type-post","status-publish","format-standard","hentry","category-exams-certification"],"_links":{"self":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts\/118521","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/comments?post=118521"}],"version-history":[{"count":0,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts\/118521\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/media?parent=118521"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/categories?post=118521"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/tags?post=118521"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}