{"id":121105,"date":"2023-10-08T15:15:44","date_gmt":"2023-10-08T15:15:44","guid":{"rendered":"https:\/\/learnexams.com\/blog\/?p=121105"},"modified":"2023-10-08T15:15:45","modified_gmt":"2023-10-08T15:15:45","slug":"cpia-examcpia-exam-test-bank-cpia-exam-cpia-exam-study-guidecpia-arena-iacuc-guidebook-cpia-exam-study-guidequestions-answers-latest-updated-a-study-guide","status":"publish","type":"post","link":"https:\/\/www.learnexams.com\/blog\/2023\/10\/08\/cpia-examcpia-exam-test-bank-cpia-exam-cpia-exam-study-guidecpia-arena-iacuc-guidebook-cpia-exam-study-guidequestions-answers-latest-updated-a-study-guide\/","title":{"rendered":"CPIA Exam:CPIA Exam Test Bank: CPIA Exam: CPIA Exam Study Guide:CPIA – ARENA IACUC Guidebook: CPIA Exam Study Guide:Questions & Answers: Latest Updated A Study Guide"},"content":{"rendered":"\n

CPIA Exam Questions & Answers
What does the Public Service Policy on Humane Care and Use of
Laboratory Animal (PHS Policy) implement?
(Ans- the Health Research Extension Act of 1985
The Health Research Extension Act of 1985 directs _ to establish guidelines for the proper care and treatment of animals used in research (Ans- the Secretary of Health and Human Services In 1986, the PHS Policy incorporated the _<\/em><\/strong><\/em><\/strong> by the Interagency
Research Animal Committee and adopted by US Government agencies
that use vertebrate animals
(Ans- U.S. Government Principles for the Utilization and Care of
Vertebrate Animals Used in Testing, Research, and Training
IACUC membership requirements for PHS Assurance
(Ans5 members:
One veterinarian (training\/experience in lab animal medicine)
One scientist (experience in research)
One nonscientific member
One not affiliated member
PHS Policy mandates that animal care and use programs must operate in
accordance with four specific laws and guidelines
(Ans1. The Animal Welfare Act<\/p>\n\n\n\n

    \n
  1. United States Government Principles for the Utilization and Care of
    Vertebrate Animals Used in Testing, Research, and Training<\/li>\n\n\n\n
  2. The Guide for the Care and Use of Laboratory Animals<\/li>\n\n\n\n
  3. AVMA Guidelines for the Euthanasia of Animals<\/li>\n<\/ol>\n\n\n\n

    Code of Federal Regulations, Title 9, Chapter 1, Subchapter A, Parts 1, 2,
    and 3
    (Ans- Animal Welfare Regulations that are implemented by the
    USDA\/APHIS\/AC
    Clarified humane care, minimization of pain and distress, consideration of
    alternatives, institutional animal care and use committees, psychological
    well-being of primates, and exercise for dogs
    (Ans- 1985 amendments to the AWA
    Which term is defined in the Guide as “all measures to control known or
    unknown infections in laboratory animals.”
    a. Biosecurity
    b. Stabilization
    c. Quarantine
    d. Biosafety
    (Ans- a. Biosecurity
    Which of the following statements about multiple survival surgical
    procedures on a single animal is TRUE?
    a. The Guide’s definition of “major” surgery is rigid, and does not provide
    for any interpretation by the veterinarian or the IACUC.
    b. When USDA-covered species are used, the Animal Welfare Regulations’
    definition of “major” surgery takes precedence.
    c. The Animal Welfare Regulations allow for the interpretation of “major”
    surgery to be evaluated on a case-by-case basis by the IACUC.
    d. The Guide’s requirement that multiple major survival surgeries must be
    scientifically justified and included in the IACUC-approved protocol only
    applies to non-rodent mammals.
    (Ans- b. When USDA-covered species are used, the Animal Welfare
    Regulations’ definition of “major” surgery takes precedence.
    Animals using which type of thermoregulation depend mostly on
    environmental temperature to maintain their internal physiology?
    (Ans- Poikilothermic
    download pdf at https:\/\/learnexams.com\/search\/study?query=<\/a><\/p>\n\n\n\n

    CPIA Exam Test Bank: CPIA Exam:
    Questions & Answers
    USDA-APHIS Animal Care Resource Policy #12 “Considerations of
    Alternatives to Painful\/Distressful Procedures” states that when a database
    search is the primary means of considerations to alternatives of painful and
    distressful procedures, that a narrative should include all of the following
    except:
    A. The name of the databases searched
    B. The date the search was performed
    C. The specific field of study
    D. The search strategy (including scientifically relevant terminology) used
    (Ans- C. The specific field of study
    Which of the following should be considered a significant change to an
    animal use proposal?
    A. change in departmental affiliation of the principal investigator
    B. change in start date of study
    C. change in anesthetic agent
    D. change in fluid administration
    (Ans- C. change in anesthetic agent
    Which of the following entities are required to release information per the
    Freedom of Information Act?
    A. OLAW
    B. AAALAC
    C. IACUC
    D. HSUS
    (Ans- A. OLAW
    Training and instruction of personnel must include guidance in which of the
    following areas?
    A. Effective writing of animal use proposals
    B. Proper use of personal protective equipment<\/p>\n\n\n\n

    C. Appropriate communication with animal activist groups
    D. Research or testing methods that limit the use of animals
    (Ans- D. Research or testing methods that limit the use of animals
    Which of the following procedures may correctly be applied to Designated
    Member Review?
    A. The IACUC Chair appoints one member to do the Designated Member
    Review.
    B. The designated member reviewer is authorized to approve, require
    modifications, or disapprove the proposal.
    C. All members receive information about the proposal and send their votes
    to the designated member reviewer for tallying.
    D. Designated member review may be utilized to review proposals when
    there is insufficient time to notify the full membership of the proposal
    details.
    (Ans- A. The IACUC Chair appoints one member to do the Designated
    Member Review.
    In which of the following circumstances may animal work begin before
    receipt of IACUC approval?
    A. It is a continuing study awaiting three year renewal and for which the
    renewal protocol has been submitted to the IACUC.
    B. It is a small pilot study on non-AWAR species.
    C. It is a teaching activity that uses students’ personally owned dogs and
    cats.
    D. There are no circumstances in which animal work may begin before
    IACUC approval.
    (Ans- D. There are no circumstances in which animal work may begin
    before IACUC approval.
    Which of the statements below about the responsibility and authority of the
    Institutional Official (IO) is false?
    A. The IO must have authority to commit institutional resources in support
    of the animal care and use program.<\/p>\n\n\n\n

    B. The IO must be the institution’s Chief Executive Officer or some
    appointed by him with authority to fund resources.
    C. The IO may reinstate an animal activity that was previously suspended
    by the IACUC.
    D. The IO may suspend an animal activity that was previously approved by
    the IACUC.
    (Ans- C. The IO may reinstate an animal activity that was previously
    suspended by the IACUC.
    With regard to conducting official IACUC business, the definition of a
    quorum is:
    A. More than fifty percent (a majority) of voting members.
    B. Fifty percent of voting and non-voting members combined.
    C. More than fifty percent (a majority) of voting and non-voting members
    combined.
    D. Fifty percent of the voting members.
    (Ans- A. More than fifty percent (a majority) of voting members
    The proper sequence for a designated member review by the IACUC is:
    A. Review materials are sent to all voting members, full committee review is
    not requested by any member, the chairperson assigns one or more
    IACUC members as designated reviewers.
    B. Review materials are sent to a quorum of designated reviewers, review
    results are solicited from designated reviewers, full committee approval of
    results is requested.
    C. Review materials are sent to all voting members, a majority of members
    do not request full committee review, the chairperson assigns one or more
    IACUC members as designated reviewers.
    D. Review materials are sent to a quorum of voting members, a majority of
    a quorum does not request full committee review, the chairperson assigns
    one or more IACUC members as designated reviewers.
    (Ans- A. Review materials are sent to all voting members, full committee
    review is not requested by any member, the chairperson assigns one or
    more IACUC members as designated reviewers.<\/p>\n\n\n\n

    Notifying investigators of IACUC protocol review outcomes in writing is:
    A. A common courtesy not required by regulatory authorities.
    B. Allowed by the USDA Animal Welfare Act Regulations and PHS Policy
    only after the minutes have been prepared and approved by the IACUC
    during a convened meeting.
    C. Required by both the USDA Animal Welfare Act Regulations and PHS
    Policy.
    D. Allowed by the USDA Animal Welfare Act Regulations and PHS Policy
    only after the IO is notified of the review outcome.
    (Ans- C. Required by both the USDA Animal Welfare Act Regulations and
    PHS Policy.
    According to the Animal Welfare Act Regulations of the USDA, when
    conducting a semi-annual evaluation, the IACUC must conduct the
    evaluation:
    A. With at least 1 IACUC member and allow participation by any member
    who wishes to do so.
    B. With at least 2 IACUC members and allow participation by any member
    who wishes to do so.
    C. With a majority of IACUC members present, including the non-affiliated
    member.
    D. With all IACUC members present.
    (Ans- B. With at least 2 IACUC members and allow participation by any
    member who wishes to do so.
    Who is given the authority to decide if a deficiency identified during a semiannual IACUC evaluation is significant or minor?
    A. The IACUC and IO together.
    B. The veterinarian and the IACUC together.
    C. Only the IACUC.
    D. Only the IO.
    (Ans- A. The IACUC and IO together.
    download pdf at     https:\/\/learnexams.com\/search\/study?query=<\/a><\/p>\n\n\n\n

    CPIA Exam Study Set: Questions &
    Answers
    True\/ False. The third Nuremberg Code states that experiments should be
    designed and based on animal experimentation.
    (Ans- True
    What year did Congress pass the Laboratory Animal Welfare Act?
    a. 1971
    b. 1963
    c. 1966
    d. 1979
    (Ans- c. 1966
    In what year was the Animal Care Panel established?
    a. 1950
    b. 1976
    c. 1963
    d. 1985
    (Ans- a. 1950
    True False, in 1963 the incorporation of the American Association for the
    Accreditation of Laboratory Animal Care (AAALAC) was established.
    (Ans- False, AAALAC was incorporated in 1965.
    In what year was the first edition of the Guide was developed?
    a. 1950
    b. 1963
    c. 1965
    d. 1967
    (Ans- b. 1963<\/p>\n\n\n\n

    True\/ False: The Animal Care Panel changed its name to the American
    Association for Laboratory Animal Science (AALAS) in 1967.
    (Ans- True
    In what year was the first Public Health Service Policy on Humane Care
    and Use of Laboratory Animals?
    a. 1971
    b. 1973
    c. 1974
    d. 1979
    (Ans- b. 1973
    Public Responsibility in Medicine and Research (PRIM&R) was established
    in which year?
    a. 1973
    b. 1974
    c. 1979
    d. 1982
    (Ans- a. 1973
    True\/False: The PHS Policy required each animal-using grantee institution
    to have a PHS Assurance and a committee to maintain oversight of its
    animal care program in 1979.
    (Ans- True
    What year was the U.S. Government Principles for the Utilization and Care
    of Vertebrate Animals Used in Testing, Research and Training
    promulgated?
    a. 1979
    b. 1982
    c. 1985
    d. 1986
    (Ans- c. 1985<\/p>\n\n\n\n

    What year was the Health Research Extension Act passed by congress?
    a. 1979
    b. 1982
    c. 1985
    d. 1986
    (Ans- c.1985
    True\/ False: The Animal Welfare Act Amendments passed by Congress in
    1985.
    (Ans- True
    AAALAC became the Association for the Assessment and Accreditation of
    Laboratory Animal Care International in what year?
    a. 1990
    b. 1991
    c. 1996
    d. 2000
    (Ans- c. 1996
    True\/False: OPRR Division of Animal Welfare was separated from OPRR
    and became the Office of Laboratory Animal Welfare (OLAW), NIH in 2002.
    (Ans- False. The OPRR Division of Animal Welfare became the Office of
    Laboratory Animal Welfare (OLAW) in 2000
    True\/ False: There are 10 U.S. Government Principles for the Utilization
    and Care of Vertebrate Animals Used in Testing, Research, and Training.
    (Ans- False. There are 9 U.S. Government Principles
    True\/ False: Risk\/ Benefit Analysis is for research that involves more than
    minimal risk of harm to the subjects, the investigator must assure that the
    amount of benefit clearly outweighs the amount of risk. Only if there is a
    favorable risk – benefit ratio may a study be considered ethical.
    (Ans- True
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    CPIA – ARENA IACUC Guidebook: CPIA
    Exam Study Guide
    Which of the following is an acceptable method of euthanasia?
    A. Decompression
    B. Carbon Dioxide
    C. Chloral Hydrate, Chloroform, and Cyanide
    D. Dry-Ice Generated CO2
    E. Neuromuscular Blockers
    (Ans- B. Carbon Dioxide
    The following methods of euthanasia are all UNACCEPTABLE:<\/p>\n\n\n\n

      \n
    1. Decompression<\/li>\n\n\n\n
    2. Chloral Hydrate, Chloroform, Cyanide<\/li>\n\n\n\n
    3. Neuromuscular Blockers<\/li>\n\n\n\n
    4. Dry Ice Generated CO2
      ARENA IACUC Guidebook, pg. 102
      Which of the 3 Rs uses a species lower on the phylogenetic scale.
      A. Reduction
      B. Refinement
      C. Replacement
      (Ans- C. Replacement
      ARENA IACUC Guidebook, pg. 97
      Which of the following describes a complete loss of sensitivity to pain?
      A. Sedation
      B. Anesthesia
      C. Analgesia
      D. Tranquilization (Ans- C. Analgesia<\/li>\n<\/ol>\n\n\n\n

      ARENA IACUC Guidebook, pg. 112
      Define Moribund
      (Ans- Moribund has been defined as “in the state of dying” or “at the point
      of death”.
      ARENA IACUC Guidebook, pg. 104
      True or False: Use of death as an endpoint must be justified in writing in
      proposals and its use must be approved by the IACUC prior to beginning a
      study. (Ans- True
      ARENA IACUC Guidebook, pg. 107
      Which regulatory entities mandate the IACUC to review protocols to ensure
      that pain and distress are minimized in laboratory animals?
      (Ans- Both the PHS Policy and the ARWs, in addition to being reiterated in
      the Guide.
      ARENA IACUC Guidebook, pg. 109
      Which of the following describes a total loss of sensation in a part or in the
      entire body?
      A. Sedation
      B. Anesthesia
      C. Analgesia
      D. Tranquilization
      (Ans- B. Anesthesia
      ARENA IACUC Guidebook, pg. 112
      Which of the following describes a state characterized by decreased
      awareness of surroundings, relaxation, and sleepiness? Analgesia is not
      present.<\/p>\n\n\n\n

      A. Sedation
      B. Anesthesia
      C. Analgesia
      D. Tranquilization
      (Ans- A. Sedation
      ARENA IACUC Guidebook, pg. 112
      Which of the following describes a state of mental calmness, decreased
      response to environmental stimuli, and muscle relaxation? No sleep,
      analgesia, or anesthesia is present, even at increased dosage.
      A. Sedation
      B. Anesthesia
      C. Analgesia
      D. Tranquilization
      (Ans- D. Tranquilization
      ARENA IACUC Guidebook, pg. 112
      Define Distress.
      (Ans- An aversive state in which an animal is unable to adapt completely to
      stressors and the resulting stress and shows maladaptive behavior.
      ARENA IACUC Guidebook, pg. 112
      Define Pain.
      (Ans- An unpleasant sensory or emotional experience associated with
      actual or potential tissue damage.
      ARENA IACUC Guidebook, pg. 112
      Which regulatory agency requires that investigators proposing procedures
      that may cause more than momentary or slight pain or distress to the
      animals will consult with the AV or his\/her designee?
      (Ans- AWRs
      download pdf at       https:\/\/learnexams.com\/search\/study?query=<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

      CPIA Exam Questions & AnswersWhat does the Public Service Policy on Humane Care and Use ofLaboratory Animal (PHS Policy) implement?(Ans- the Health Research Extension Act of 1985The Health Research Extension Act of 1985 directs _ to establish guidelines for the proper care and treatment of animals used in research (Ans- the Secretary of Health and […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[25],"tags":[],"class_list":["post-121105","post","type-post","status-publish","format-standard","hentry","category-exams-certification"],"_links":{"self":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts\/121105","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/comments?post=121105"}],"version-history":[{"count":0,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts\/121105\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/media?parent=121105"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/categories?post=121105"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/tags?post=121105"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}