{"id":127393,"date":"2023-11-26T15:56:24","date_gmt":"2023-11-26T15:56:24","guid":{"rendered":"https:\/\/learnexams.com\/blog\/?p=127393"},"modified":"2023-11-26T15:56:26","modified_gmt":"2023-11-26T15:56:26","slug":"nr-565-nr565-advanced-pharmacology-midterm-exam-review-already-rated-a-latest-2021-2022-chamberlain-college","status":"publish","type":"post","link":"https:\/\/www.learnexams.com\/blog\/2023\/11\/26\/nr-565-nr565-advanced-pharmacology-midterm-exam-review-already-rated-a-latest-2021-2022-chamberlain-college\/","title":{"rendered":"NR 565 \/ NR565 Advanced Pharmacology Midterm Exam Review | Already Rated A | Latest, 2021\/2022| Chamberlain College"},"content":{"rendered":"\n<p>NR 565 \/ NR565 Advanced Pharmacology Midterm Exam Review | Already Rated A | Latest, 2021\/2022| Chamberlain College<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><a href=\"https:\/\/learnexams.com\/search\/study?query=\" target=\"_blank\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/learnexams.com\/blog\/wp-content\/uploads\/2023\/11\/download-2023-11-26T185522.126-725x1024.png\" alt=\"\" class=\"wp-image-127394\"\/><\/a><\/figure>\n\n\n\n<p>NR 565 \/ NR565 Advanced<br>Pharmacology Midterm Exam Review<br>| Already Rated A | Latest, 2021\/2022|<br>Chamberlain College<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li>What is the significance of VCORC1 mutation?<\/li>\n<\/ol>\n\n\n\n<ul class=\"wp-block-list\">\n<li>The significance of the VCORC1 mutation is that it is related to an<br>individual exhibiting warfarin resistance since it plays a role in<br>metabolizing the drug warfarin (Woo et al., 2016).<\/li>\n\n\n\n<li>This means that the individual is prone to an increased risk of bleeding<br>which can lead to adverse outcomes for the individuals who exhibit this<br>genetic mutation (Fereidouni et al., 2019).<\/li>\n\n\n\n<li>The VCORC1 mutation is responsible for producing a &#8220;subunit of the<br>vitamin K epoxide reductase complex&#8221; (Woo et al., 2016).<\/li>\n\n\n\n<li>It is currently not required by the FDA to complete genetic testing prior<br>to starting warfarin, but as practitioners we should encourage our<br>patients to complete genetic testing so that we can accurately calculate the<br>correct dosage for warfarin without creating significant adverse outcomes<br>for these individuals.<\/li>\n<\/ul>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Can you describe how new drugs are developed from the text?<\/li>\n<\/ol>\n\n\n\n<ul class=\"wp-block-list\">\n<li>New drugs are developed by researches in a lab first by looking into<br>disease processes and the medications that are used to help treat these<br>disease processes.<\/li>\n\n\n\n<li>After looking at the medications to help treat disease better, researches<br>look into how to make the medications be more effective with less toxicity<br>or &#8216;side effects&#8217;. in order to do this, researchers start preclinical research.<\/li>\n\n\n\n<li>During this phase researchers look into whether the drug is going to kill<br>people or cause serious harm to people. then they go into the clinical<br>phase.<\/li>\n\n\n\n<li>The clinical phase is where they use the preclinical phase data and come<br>up with human research subjects. These usually consist of two groups<br>(one getting the new medication and one getting a &#8216;fake&#8217; medication<br>(placebo).<\/li>\n\n\n\n<li>Then this leads to step 4 the FDA drug review where they come up with<br>labels, safety updates, etc. Then they move on to the post market<br>monitoring where they actually pay attention to the way the medication is<br>being used and what for. (US Food and Drug Administration, 2018)<\/li>\n<\/ul>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Explain what it means if a drug is an antagonist?<\/li>\n<\/ol>\n\n\n\n<ul class=\"wp-block-list\">\n<li>An antagonist according to our text is a drug that takes over a receptor<br>without stimulating that receptor.<\/li>\n\n\n\n<li>We see the medication blocking the response of an agonist to that<br>receptor. Such as seen in a beta-blocker keeping the adrenergic nerve<br>activity from increasing the heart rate and therefore able to help decrease<\/li>\n<\/ul>\n\n\n\n<p>the heart rate of the patient taking the medication. Antagonists can make<br>the agonist appear less potent.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>The effect of the antagonist depends on that of the affinity for the<br>receptor and the blood levels noted in the patient (Woo RN PhD ARNP<br>CPNP-PC CNL FAANP, Teri Moser et al., 2015).<\/li>\n\n\n\n<li>Another example would be naltrexone. This medication is used in patients<br>that want to not relapse in heroin or opioid usage.<\/li>\n\n\n\n<li>The medication blocks the receptors for the opioids and does not allow<br>the drugs to connect to the receptors.<\/li>\n\n\n\n<li>The problem with this is that it can cause an overdose if there is a relapse<br>(Pharmacological Treatment | Medication Assisted Recovery, n.d.).<\/li>\n<\/ul>\n\n\n\n<ol class=\"wp-block-list\">\n<li>What the terms efficacy and bioavailability mean?<\/li>\n<\/ol>\n\n\n\n<ul class=\"wp-block-list\">\n<li>According to Woo &amp; Robinson (2016), efficacy in medicine means the<br>power of producing the maximum effect of a drug (Woo &amp; Robinson,<br>2016, p. 14).<\/li>\n\n\n\n<li>When thinking about efficacy and medication, an example may include<br>hypertension medication and how it lowers blood pressure but can also<br>have an effect on other mechanisms in the body such as heart rate or<br>kidney function.<\/li>\n\n\n\n<li>Patients who are prescribed new medication should be monitored closely<br>on how it may affect the patient&#8217;s outcome. It also states that drugs with<br>Powered by <a href=\"https:\/\/learnexams.com\/search\/study?query=\" target=\"_blank\" rel=\"noopener\">https:\/\/learnexams.com\/search\/study?query=<\/a><\/li>\n<\/ul>\n\n\n\n<div data-wp-interactive=\"core\/file\" class=\"wp-block-file\"><object data-wp-bind--hidden=\"!state.hasPdfPreview\" hidden class=\"wp-block-file__embed\" data=\"https:\/\/learnexams.com\/blog\/wp-content\/uploads\/2023\/11\/nr-565-nr565-advanced-pharmacology-midterm-exam-review-already-rated-a-latest-20212022-chamberlain-college.pdf\" type=\"application\/pdf\" style=\"width:100%;height:600px\" aria-label=\"Embed of nr-565-nr565-advanced-pharmacology-midterm-exam-review-already-rated-a-latest-20212022-chamberlain-college.\"><\/object><a id=\"wp-block-file--media-22ce4762-6628-4794-af86-0e0636c8910f\" href=\"https:\/\/learnexams.com\/blog\/wp-content\/uploads\/2023\/11\/nr-565-nr565-advanced-pharmacology-midterm-exam-review-already-rated-a-latest-20212022-chamberlain-college.pdf\" target=\"_blank\" rel=\"noopener\">nr-565-nr565-advanced-pharmacology-midterm-exam-review-already-rated-a-latest-20212022-chamberlain-college<\/a><a href=\"https:\/\/learnexams.com\/blog\/wp-content\/uploads\/2023\/11\/nr-565-nr565-advanced-pharmacology-midterm-exam-review-already-rated-a-latest-20212022-chamberlain-college.pdf\" class=\"wp-block-file__button wp-element-button\" aria-describedby=\"wp-block-file--media-22ce4762-6628-4794-af86-0e0636c8910f\" download target=\"_blank\" rel=\"noopener\">Download<\/a><\/div>\n","protected":false},"excerpt":{"rendered":"<p>NR 565 \/ NR565 Advanced Pharmacology Midterm Exam Review | Already Rated A | Latest, 2021\/2022| Chamberlain College NR 565 \/ NR565 AdvancedPharmacology Midterm Exam Review| Already Rated A | Latest, 2021\/2022|Chamberlain College the heart rate of the patient taking the medication. Antagonists can makethe agonist appear less potent.<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[25],"tags":[],"class_list":["post-127393","post","type-post","status-publish","format-standard","hentry","category-exams-certification"],"_links":{"self":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts\/127393","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/comments?post=127393"}],"version-history":[{"count":0,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts\/127393\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/media?parent=127393"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/categories?post=127393"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/tags?post=127393"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}