{"id":127397,"date":"2023-11-26T15:58:30","date_gmt":"2023-11-26T15:58:30","guid":{"rendered":"https:\/\/learnexams.com\/blog\/?p=127397"},"modified":"2023-11-26T15:58:31","modified_gmt":"2023-11-26T15:58:31","slug":"nr-565-nr565-advanced-pharmacology-final-exam-review-already-rated-a-latest-2021-2022-chamberlain-college","status":"publish","type":"post","link":"https:\/\/www.learnexams.com\/blog\/2023\/11\/26\/nr-565-nr565-advanced-pharmacology-final-exam-review-already-rated-a-latest-2021-2022-chamberlain-college\/","title":{"rendered":"NR 565 \/ NR565 Advanced Pharmacology Final Exam Review | Already Rated A | Latest, 2021\/2022| Chamberlain College"},"content":{"rendered":"\n<p>NR 565 \/ NR565 Advanced Pharmacology Final Exam Review | Already Rated A | Latest, 2021\/2022| Chamberlain College<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><a href=\"https:\/\/learnexams.com\/search\/study?query=\" target=\"_blank\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/learnexams.com\/blog\/wp-content\/uploads\/2023\/11\/download-2023-11-26T185711.338-725x1024.png\" alt=\"\" class=\"wp-image-127398\"\/><\/a><\/figure>\n\n\n\n<p>NR 565 \/ NR565 Advanced<br>Pharmacology Final Exam Review |<br>Already Rated A | Latest, 2021\/2022|<br>Chamberlain College<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li>gastroesophageal reflux disease (GERD)<\/li>\n<\/ol>\n\n\n\n<ul class=\"wp-block-list\">\n<li>common disorder characterized by heartburn and acid regurgitation.<\/li>\n<\/ul>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Major groups of GERD<\/li>\n<\/ol>\n\n\n\n<ul class=\"wp-block-list\">\n<li>erosive esophagitis and<\/li>\n\n\n\n<li>non-erosive reflux disease (NERD).<\/li>\n<\/ul>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Drug of choice for GERD<\/li>\n<\/ol>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Proton Pump Inhibitors;<\/li>\n<\/ul>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Cimetidine use for GERD<\/li>\n<\/ol>\n\n\n\n<ul class=\"wp-block-list\">\n<li>drug of choice for relieving symptoms.; does little to hasten healing.<\/li>\n<\/ul>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Proton Pump Inhibitor MOA<\/li>\n<\/ol>\n\n\n\n<ul class=\"wp-block-list\">\n<li>irreversibly blocking hydrogen and the amount of HCl produced by the stomach<\/li>\n<\/ul>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Proton Pump Inhibitor Prototype Drug<\/li>\n<\/ol>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Omeprazole<\/li>\n<\/ul>\n\n\n\n<ol class=\"wp-block-list\">\n<li>PPI AE<\/li>\n<\/ol>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Pneumonia,<\/li>\n\n\n\n<li>FX,<\/li>\n\n\n\n<li>Rebound Acid Hypersecretion,<\/li>\n\n\n\n<li>Hypomagnesemia<\/li>\n<\/ul>\n\n\n\n<ol class=\"wp-block-list\">\n<li>PPI Monitoring<\/li>\n<\/ol>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Magnesium (Hypomagnesimia)<\/li>\n<\/ul>\n\n\n\n<ol class=\"wp-block-list\">\n<li>PPI Drug Interaction<\/li>\n<\/ol>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Clopidogrel (Plavix)<\/li>\n<\/ul>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Antidiarrheal drugs fall into two major groups<\/li>\n<\/ol>\n\n\n\n<ul class=\"wp-block-list\">\n<li>(1) specific antidiarrheal drugs: Treat the underlying causative agent<\/li>\n\n\n\n<li>(2) nonspecific antidiarrheal drugs: Treat the symptom but do not treat the agent<\/li>\n<\/ul>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Opioids (antidiarrheals)<\/li>\n<\/ol>\n\n\n\n<ul class=\"wp-block-list\">\n<li>most effective antidiarrheal agents;<\/li>\n\n\n\n<li>activating opioid receptors in the GI tract,<\/li>\n\n\n\n<li>these drugs decrease intestinal motility and thus slow down intestinal transit,<br>which allows more time for absorption of fluid and electrolytes.<\/li>\n<\/ul>\n\n\n\n<ol class=\"wp-block-list\">\n<li>diphenoxylate (Lomotil, others) and loperamide (Imodium, others)<\/li>\n<\/ol>\n\n\n\n<ul class=\"wp-block-list\">\n<li>most frequently employed opioids for diarrhea<\/li>\n<\/ul>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Diphenoxylate (Lomotil)<\/li>\n<\/ol>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Opioid Antidiarrheal; Formulated w\/ atropine to discourage abuse<\/li>\n<\/ul>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Diphenoxylate (Lomotil) MOA<\/li>\n\n\n\n<li>Loperamide (Imodium)<\/li>\n<\/ol>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Opioid Antidiarrheal; Meperidine analog<\/li>\n<\/ul>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Loperamide (Imodium) MOA<\/li>\n<\/ol>\n\n\n\n<ul class=\"wp-block-list\">\n<li>treat diarrhea and reduce the volume of discharge from ileostomies.<\/li>\n\n\n\n<li>Benefits derive from suppressing bowel motility and from suppressing fluid<br>secretion into the intestinal lumen.<\/li>\n<\/ul>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Bismuth subsalicylate (Pepto-Bismol)<\/li>\n<\/ol>\n\n\n\n<ul class=\"wp-block-list\">\n<li>-popular over-the-counter medication that can be used for upset stomach,<br>diarrhea, heartburn, and general indigestion.<\/li>\n\n\n\n<li>-antibacterial and antisecretory properties; used to treat traveler&#8217;s diarrhea<\/li>\n<\/ul>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Bismuth subsalicylate (Pepto-Bismol) Contraindication<\/li>\n<\/ol>\n\n\n\n<ul class=\"wp-block-list\">\n<li>contraindicated in children or teenagers during or after recovery from chickenpox<br>or flu-like illness due to the risk of Reye&#8217;s syndrome and in individuals with<br>aspirin hypersensitivity.<\/li>\n<\/ul>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Bismuth subsalicylate (Pepto-Bismol) AE<\/li>\n<\/ol>\n\n\n\n<ul class=\"wp-block-list\">\n<li>gray\/black stools and<\/li>\n\n\n\n<li>black tongue from the bismuth.<\/li>\n<\/ul>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Traveler&#8217;s diarrhea<\/li>\n<\/ol>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Escherichia coli<\/li>\n<\/ul>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Traveler&#8217;s Diarrhea Treatment<\/li>\n<\/ol>\n\n\n\n<ul class=\"wp-block-list\">\n<li>-Ciprofloxacin for adults.<\/li>\n\n\n\n<li>-Azithromycin (Zithromax) is preferred for children and for pregnant women).<\/li>\n\n\n\n<li>-Rifaximin (Xifaxan) may also be used provided the patient is not pregnant or<br>febrile and that stools are not bloody.<\/li>\n<\/ul>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Metoclopramide MOA<\/li>\n<\/ol>\n\n\n\n<ul class=\"wp-block-list\">\n<li>A prokinetic agent:<br>(1) suppresses emesis (by blocking receptors for dopamine and serotonin in<br>the CTZ)<br>(2) it increases upper GI motility (by enhancing the actions of<br>acetylcholine).<\/li>\n<\/ul>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Prokinetic Agent<\/li>\n<\/ol>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Metoclopramide; Drugs that increase the tone and motility of the GI tract.<br>Indications include gastroesophageal reflux disease (GERD), CINV, and diabetic<br>gastroparesis.<\/li>\n<\/ul>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Metoclopramide (Reglan) PO Dose Use<\/li>\n<\/ol>\n\n\n\n<ul class=\"wp-block-list\">\n<li>1) diabetic gastroparesis<\/li>\n\n\n\n<li>2) suppression of gastroesophageal reflux.<\/li>\n<\/ul>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Metoclopramide (Reglan) IV Dose Use<\/li>\n<\/ol>\n\n\n\n<ul class=\"wp-block-list\">\n<li>1) suppression of postoperative nausea and vomiting,<\/li>\n\n\n\n<li>2) suppression of CINV,<\/li>\n\n\n\n<li>3) facilitation of small bowel intubation<\/li>\n\n\n\n<li>4) facilitation of radiologic examination of the GI tract.<\/li>\n<\/ul>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Metoclopramide (Reglan) AE<\/li>\n<\/ol>\n\n\n\n<ul class=\"wp-block-list\">\n<li>High-dose therapy: sedation and diarrhea are common<\/li>\n\n\n\n<li>Long-term high-dose therapy: irreversible tardive dyskinesia, characterized by<br>repetitive, involuntary movements of the arms, legs, and facial muscles.<\/li>\n<\/ul>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Metoclopramide contraindication<\/li>\n<\/ol>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Contraindication in patients with GI obstruction, perforation, or hemorrhage.<\/li>\n<\/ul>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Misoprostol (Cytotec)<\/li>\n<\/ol>\n\n\n\n<ul class=\"wp-block-list\">\n<li>an analog of prostaglandin E1. In the United States, the drug&#8217;s only approved GI<br>indication is prevention of gastric ulcers caused by long-term therapy with<br>NSAIDs.<\/li>\n<\/ul>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Misoprostol (Cytotec) Contraindication<\/li>\n<\/ol>\n\n\n\n<ul class=\"wp-block-list\">\n<li>contraindicated during pregnancy due to risk for partial or complete expulsion of<br>the developing fetus.<\/li>\n<\/ul>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Peptic Ulcer Disease Step 2 Therapy<\/li>\n<\/ol>\n\n\n\n<ul class=\"wp-block-list\">\n<li>H. pylori testing &amp; Treatment with PPIs<\/li>\n<\/ul>\n\n\n\n<ol class=\"wp-block-list\">\n<li>H. pylori<\/li>\n<\/ol>\n\n\n\n<ul class=\"wp-block-list\">\n<li>gram-negative bacillus that can colonize the stomach and duodenum; most<br>common cause of gastric and duodenal ulcers<\/li>\n<\/ul>\n\n\n\n<ol class=\"wp-block-list\">\n<li>H. Pylori Treatment<\/li>\n<\/ol>\n\n\n\n<ul class=\"wp-block-list\">\n<li>PPI plus antibiotics<\/li>\n<\/ul>\n\n\n\n<ol class=\"wp-block-list\">\n<li>H. pylori triple therapy<\/li>\n<\/ol>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Amoxicillin,<\/li>\n\n\n\n<li>Clarithromycin or<\/li>\n\n\n\n<li>Metronidazole, PPI (omeprazole)<\/li>\n<\/ul>\n\n\n\n<ol class=\"wp-block-list\">\n<li>H. pylori quadruple therapy<\/li>\n<\/ol>\n\n\n\n<ul class=\"wp-block-list\">\n<li>PPI,<\/li>\n\n\n\n<li>bismuth,<\/li>\n\n\n\n<li>metronidazole,<br>Powered by <a href=\"https:\/\/learnexams.com\/search\/study?query=\" target=\"_blank\" rel=\"noopener\">https:\/\/learnexams.com\/search\/study?query=<\/a><\/li>\n<\/ul>\n\n\n\n<div data-wp-interactive=\"core\/file\" class=\"wp-block-file\"><object data-wp-bind--hidden=\"!state.hasPdfPreview\" hidden class=\"wp-block-file__embed\" 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College<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center 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