{"id":130151,"date":"2023-12-07T00:07:14","date_gmt":"2023-12-07T00:07:14","guid":{"rendered":"https:\/\/learnexams.com\/blog\/?p=130151"},"modified":"2023-12-07T00:07:15","modified_gmt":"2023-12-07T00:07:15","slug":"nbcrna-exam-questions-latest-2023-2024-actual-exam","status":"publish","type":"post","link":"https:\/\/www.learnexams.com\/blog\/2023\/12\/07\/nbcrna-exam-questions-latest-2023-2024-actual-exam\/","title":{"rendered":"NBCRNA EXAM QUESTIONS LATEST 2023-2024 ACTUAL EXAM"},"content":{"rendered":"\n

What muscarinic antagonist causes the most sedation? – ANSWER\u0002scopolamine
Opioid receptor MOA – ANSWER- opioid binds to receptor, activates G
protein, adenylate cyclase is inhibited, cAMP is inhibited, Ca
conductance is decreased, K conductance is increased
What are the endogenous ligands of mu, kappa, and delta receptors? –
ANSWER- mu = endorphins
kappa = dynorphins
delta = enkephalins
Key side effects of kappa receptor stimulation – ANSWER- dysphoria,
antishivering, diuresis
Which body fluid normally has a higher concentration of protein? –
ANSWER- intracellular fluid

What is the major intracellular anion? cation? – ANSWER- anion =
phosphate
cation = potassium
Which term refers to the amount of the drug that is able to reach its
target receptor after it is introduced into the circulatory system? –
ANSWER- bioavailability
Which Phase 1 reaction is characterized by reactions that remove
electrons from a molecule? – ANSWER- oxidation
What term refers to the dose of a drug required to produce a given effect
in 50 percent of subjects? – ANSWER- potency
Approximately what portion of the total amount of body water is
intracellular? – ANSWER- 2\/3rds
LA’s exist as weak (acids or bases) with a (positively or negatively)
charged amine group – ANSWER- weak bases and positively charged
amine group
Etomidate may cause a slight decrease in BP due to what? – ANSWER\u0002decrease in SVR

Rocuronium ED95 – ANSWER- 0.3 mg\/kg
opioid potency compared to 10 mg morphine (alfentanil, fentanyl,
remifentanil, sufentanil, ketorolac, meperidine, hydromorphone) –
ANSWER- alfentanil = 1 mg
fentanyl = 100 mcg
remifentanil = 100 mcg
sufentanil = 10 mcg
ketorolac = 30 mg
meperidine = 100 mg
hydromorphone = 1.5 mg
Basic vs acidic drugs protein binding – ANSWER- basic = alpha 1
glycoprotein
acidic = albumin

max dosages of local anesthetics – ANSWER- lidocaine\/mepivacaine = 4
mg\/kg or 7 mg\/kg with epi
bupivacaine\/ropivacaine = 2 mg\/kg or 3 mg\/kg with epi
2CP = 15 mg\/kg or 20 mg\/kg with epi
what drugs are in class I antiarrhythmics? – ANSWER- IA = quinidine,
procainamide HCl, disopyramide
IB = lidocaine, mexilitine HCl, tocainide, phenytoin
IC = flecainide acetate, propafenone HCl
Lidocaine affects what phase of the action potential to serve as an
antiarrhythmic? – ANSWER- affects phase 0 (influx of Na)
What drugs are useful to treat pulmonary HTN? – ANSWER- iloprost,
epoprostenol, PDE-V inhibitors (sildenafil), endothelin 1 antagonists
(bosentan), inhaled nitric oxide
PDE-_<\/em> inhibitors are useful for pulmonary HTN – ANSWER- 5
Risk of mendelson syndrome when aspirate volume and pH is what? –
ANSWER- volume over 25 cc and pH less than 3<\/p>\n\n\n\n

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