{"id":132075,"date":"2024-02-02T07:30:41","date_gmt":"2024-02-02T07:30:41","guid":{"rendered":"https:\/\/learnexams.com\/blog\/?p=132075"},"modified":"2024-02-02T07:30:43","modified_gmt":"2024-02-02T07:30:43","slug":"exam-1-nr293-nr-293-latest-update-2024-2025-pharmacology-review-complete-guide-with-questions-and-verified-answers-100-correct-chamberlain","status":"publish","type":"post","link":"https:\/\/www.learnexams.com\/blog\/2024\/02\/02\/exam-1-nr293-nr-293-latest-update-2024-2025-pharmacology-review-complete-guide-with-questions-and-verified-answers-100-correct-chamberlain\/","title":{"rendered":"Exam 1: NR293 \/ NR 293 (Latest Update 2024\/2025) Pharmacology Review| Complete Guide with Questions and Verified Answers| 100% Correct -Chamberlain"},"content":{"rendered":"\n<p>Exam 1: NR293 \/ NR 293 (Latest Update 2024\/2025) Pharmacology Review| Complete Guide with Questions and Verified Answers| 100% Correct -Chamberlain<\/p>\n\n\n\n<p>Exam 1: NR293 \/ NR 293 (Latest Update<br>2024\/2025) Pharmacology Review| Complete<br>Guide with Questions and Verified Answers|<br>100% Correct -Chamberlain<br>Q: Pharmacotherapeutics<br>Answer:<br>treatment of conditions<br>Q: enteral route<br>Answer:<br>through the GI tract<br>Q: parenteral tract<br>Answer:<br>outside the GI tract<br>Q: how is medication absorption different for neonates and children?<br>Answer:<br>they have less gastric acid to break down medications and availability is higher<br>Q: why do more drugs enter neonate and children&#8217;s brains, why are meds not as easily<br>excreted\/destroyed by liver and kidneys ?<\/p>\n\n\n\n<p>Answer:<br>immature BBB, liver, and kidneys<br>Q: Polypharmacy<br>Answer:<br>The use of multiple medications on a regular basis<br>Q: during which phase of the nursing process does a nurse prioritize the nursing diagnoses?<br>Answer:<br>planning<br>Q: the nurse recognizes that drugs given by which route will be altered by the first pass effect?<br>a. oral<br>b. sublingual<br>c. subcutaneous<br>d. IV<br>e. rectal<br>Answer:<br>oral and rectal<br>Q: the nurse is reviewing a list of a patient&#8217;s medications and notes one of the drugs has a low<br>therapeutic index. what does this mean?<br>Answer:<br>the difference between a therapeutic dose and a toxic dose are very close together<\/p>\n\n\n\n<p>Q: when drug A is an enzyme inhibitor of drug B, the nurse will anticipate what result of drug<br>B?<br>Answer:<br>level of drug B could rise to toxicity<br>Q: A drug is highly protein bound, what does this mean?<br>Answer:<br>it will have a longer duration of action<br>Q: do no harm is what ethical principle?<br>Answer:<br>nonmaleficence<br>Q: Which legal act required drug manufacturers to establish the safety and efficacy of a new<br>drug before its approval for use?<br>Answer:<br>Kefauver-Harris, amendment of 1962<br>Q: over the counter drugs (otc) are<br>Answer:<br>nonprescription drugs that are used for short term treatment<br>Q: what herbal supplement is used to promote sleep and relaxation, prolonged use can cause<br>yellow discoloration of nails, risk for liver toxicity<\/p>\n\n\n\n<p>Answer:<br>kava<br>Q: herbal supplement used to decrease nausea and vomiting induced by chemotherapy<br>Answer:<br>ginkgo<br>Q: which drug classes are used as OTC remedies ?<br>a. NSAIDs<br>b. cold remedies<br>c. antibiotics<br>d.smoking deterrent drugs<br>e. antihypertensive drugs<br>f. histamine 2 (H2) blockers<br>Answer:<br>A, B,D,F<br>Q: what are side effects of NSAIDs?<br>Answer:<br>stroke, MI, GI ulcers, kidney dysfunction<br>Q: what do antibiotics do?<br>Answer:<br>fight off infection caused by bacteria<br>Powered by <a href=\"https:\/\/learnexams.com\/search\/study?query=NR\" target=\"_blank\" rel=\"noopener\">https:\/\/learnexams.com\/search\/study?query=NR<\/a><br>Risks for injury know that anything can be a possible risk for patient injury<br>9 rights of medicine administration right patient, right dose, right medication, right time, right documentation, right route, right reason, right response<br>what is a prototype the first drug of a class that all others are based from (ex- morphine)<br>what is pharmacokinetics what the body does to the drug<br>what is pharmacodynamics what the drug does to the body<br>bioavailability what portion of the drug that entered the circulation can have an effect on the body<br>first pass effect a drug enters the GI tract and is filtered to the liver where some is destroyed<br>what enzymes work in the liver P-450 enzymes<br>if a patient has cirrhosis of the liver, what will happen when they take a medication? When the medication passes through the liver for the first pass, there will be less P-450 enzymes so the bioavailability of the medication will be higher and it will circulate in the bloodstream longer.<br>half life time required for 50% of the drug to be removed from the body<br>Pharmacotherapeutics treatment of conditions<br>enteral route through the GI tract<br>parenteral tract outside the GI tract<br>how is medication absorption different for neonates and children? they have less gastric acid to break down medications and availability is higher<br>why do more drugs enter neonate and children&#8217;s brains, why are meds not as easily excreted\/destroyed by liver and kidneys ? immature BBB, liver, and kidneys<br>Polypharmacy The use of multiple medications on a regular basis<br>during which phase of the nursing process does a nurse prioritize the nursing diagnoses? planning<br>the nurse recognizes that drugs given by which route will be altered by the first pass effect? a. oralb. sublingualc. subcutaneous d. IVe. rectal oral and rectal<br>the nurse is reviewing a list of a patient&#8217;s medications and notes one of the drugs has a low therapeutic index. what does this mean? the difference between a therapeutic dose and a toxic dose are very close together<br>when drug A is an enzyme inhibitor of drug B, the nurse will anticipate what result of drug B? level of drug B could rise to toxicity<br>A drug is highly protein bound, what does this mean? it will have a longer duration of action<br>do no harm is what ethical principle? nonmaleficence<br>Which legal act required drug manufacturers to establish the safety and efficacy of a new drug before its approval for use? Kefauver-Harris, amendment of 1962<br>over the counter drugs (otc) are nonprescription drugs that are used for short term treatment<br>what herbal supplement is used to promote sleep and relaxation, prolonged use can cause yellow discoloration of nails, risk for liver toxicity kava<br>herbal supplement used to decrease nausea and vomiting induced by chemotherapy ginkgo<br>which drug classes are used as OTC remedies ?a. NSAIDsb. cold remedies c. antibiotics d.smoking deterrent drugs e. antihypertensive drugs f. histamine 2 (H2) blockers A, B,D,F<br>what are side effects of NSAIDs? stroke, MI, GI ulcers, kidney dysfunction<br>what do antibiotics do? fight off infection caused by bacteria<br>Bacteriostatic doesn&#8217;t kill bacteria, it inhibits growth<br>bactericidal kills bacteria<br>healthcare associated infections are contracted in a hospital or institution (>48 hours after admin) , are more difficult to treat, and are more virulent<br>antiseptics are used for living tissue, inhibit growth of bacteria<br>disinfectants used on nonliving tissue, destroy\/kill organisms<br>what is a priority of the nurse to perform before beginning an antibiotic therapy? obtain a culture and sensitivity specimen<br>prophylactic therapy preventative measure, antibiotics given before a procedure to ensure that an infection will not start<br>empiric therapy treatment of an infection before c+s information has been obtained or reported<br>definitive therapy treatment of a specific infection after receiving repot of c+s<br>what two classes of antibiotics are common for causing allergic reactions? penicillins and sulfonamides<br>if a person is allergic to penicillin, what other class of antibiotics should be looked into? cephalosporins<br>what is the main example of sulfonamides? Bactrim<br>what must Bactrim be taken with? 2000-3000 mL of H20\/ day<br>what is the MOA of sulfonamides ? bacteriostatic<br>Indications for sulfonamides broad spectrum, gram + or -; UTIs<br>adverse effects of sulfonamides SJS, photosensitivity<br>contraindications of sulfonamides allergy, pregnancy<br>what are the main examples of Beta Lactams- penicillins amoxicillin, ampicillin<br>penicillins MOA bactericidal<br>indications of penicillins gram + ; strep throat<br>adverse effects of penicillins pruritus, GI upset, throat swelling<br>contraindications of penicillins allergy, renal failure<br>Cephalosporins Gen 1 cefalexin and cefazolin (surgical prophylaxis and staph)<br>Cephalosporins Gen 2 cefoxitin (abdominal surgery, colorectal)<br>Cephalosporins Gen 3 cefidinir and ceftrixone (meningitis)<br>Cephalosporins Gen 4 cefedime (uncomplicated UTI)<br>cephalosporins Gen 5 ceftaroline (MRSA)<br>cephalosporins MOA bactericidal<br>cephalosporins indications 1st gen: good +, poor -2nd gen: good +, better -3rd gen: gram -4th gen: +, some -5th gen: broad spectrum<br>cephalosporins adverse effects SJS, rash, cross sensitivity with penicillins, GI upset<br>cephalosporins contraindications allergy to penicillin<br>cephalosporins nursing implications must infuse slowly<br>what is the main example of carbapenems? meropenem (merrem)<br>carbapenems MOA bacteriostatic<br>carbapenems indications broadest spectrum; complicated body cavity infections, bone, joints, tissue<br>carbapenems adverse effects drug induced seizure<br>carbapenems contraindications hypersensitivity, seizures<br>carbapenems nursing implications infuse over 60 minutes<br>ketolides main example telithromycin (ketek)<br>ketolides MOA bacteriostatic<br>ketolides indications limited use, pneumonia<br>ketolides adverse effects hepatotoxicity, GI upset, rash, fatigue<br>Ketolides Contraindications severe liver disease<br>main example of monobactams Azactam<br>monobactams MOA bactericidal<br>monobactams indications UTI, moderate-severe systemic infections<br>monobactams adverse effects GI upset, rash, fever<br>monobactams contraindication hypersensitivity, GI upset<br>macrolides main examples Azithromycin (Zithromax) and erythromycin (E-mycin)<br>macrolides MOA bacteriostatic<br>macrolides indications STIs and lyme disease<br>macrolides adverse effects GI upset and jaundice<br>Macrolides contraindications liver disease, bradycardia<br>Tetracyclines main example Tetracycline<br>Tetracyclines MOA bacteriostatic<br>Tetracyclines indications broad spectrum<br>Tetracyclines adverse effects discoloration of permanent teeth, disturbs growth<br>Tetracyclines Contraindications pregnancy, children &lt;8 yrs ; photosensitivity<br>Tetracyclines Nursing Implications Avoid milk products, antacids, and other dairy products; Take all medications with 6 to 8 ounces of fluid, preferably water, avoid sunlight and tanning beds<br>aminoglycosides examples Neomycin (swimmers ear) Gentamycin (UTI)<br>aminoglycosides MOA bactericidal<br>aminoglycosides indications Life-threatening infections, sepsis<br>aminoglycosides adverse effects OTOTOXIC and NEPHROTOXIC<br>aminoglycosides contraindications Known allergies, renal or hepatic disease, hearing loss<br>aminoglycosides nursing implications monitor I+O, BUN, and creatinine<br>quinolones main examples ciprofloxacin (Cipro) and Levofloxacin (Levaquin)<br>quinolones MOA bactericidal<br>quinolones indications Bone and joint infections,UTIs<br>quinolones adverse effects QT prolongation, tendon rupture<br>Quinolones contraindications ehler&#8217;s danlose syndrome, prolonged QT interval, pregnancy, children<br>Quinolones Nursing Implications Infuse over 1 to 1.5 hours ;Vitamin K is affected &#8211; caution with warfarin<br>misc- Clindamycin (cleocin) MOA bacteriostatic<br>misc- Clindamycin (cleocin) indications septicemia<br>misc- Clindamycin (cleocin) adverse effects thrush and GI upset<br>misc- Clindamycin (cleocin) contraindications GI conditions, c-diff, skeletal muscle disorders<br>MISC- Clindamycin (cleocin) nursing implications may react with muscle relaxants<br>MISC: Linezolid (Zyvox) MOA bactericidal<br>MISC: Linezolid (Zyvox) indications VRE (vancomycin resistant enterococcal )<br>MISC: Linezolid adverse effects hypotension, serotonin syndrome<br>MISC: Linezolid (Zyvox) contraindications pregnancy and breast feeding<br>MISC: Linezolid (Zyvox) nursing implications reacts with TYRAMINE containing food<br>(Misc.) Metronidazole (Flagyl) MOA bactericidal<br>(Misc.) Metronidazole (Flagyl) indications intra-abdominal and gynecological infections<br>(Misc.) Metronidazole (Flagyl) adverse effects fatal hepatotoxicity<br>(Misc.) Metronidazole (Flagyl) contraindications renal impairment<br>(Misc.) Metronidazole (Flagyl) nursing implications interacts with several other medications<br>(Misc.) Vancomycin (Vancocin) MOA bactericidal<br>(Misc.) Vancomycin (Vancocin) indications meningitis, MRSA<br>(Misc.) Vancomycin (Vancocin) adverse effects ototoxicity and nephrotoxicity; red man syndrome<br>(Misc.) Vancomycin (Vancocin) contraindications renal or hearing impairment<br>(Misc.) Vancomycin (Vancocin) nursing implications MUTS BE RUN ALONE. slow the infusion to avoid RMSmonitor IV site and for signs of anaphylaxis<br>a nurse is reviewing the drugs ordered for a patient. A drug interaction occurs with penicillin and this drug. Which could they be?a. alcoholb. oral contraceptivesc. digoxin d. NSAIDs e. Warfarin f. anticonvulsants b,d,e<br>the nurse knows that the use of tetracyclines is restricted in children nuder 8 because of what effect? a. stunting of growth platesb. threat of sunburn c. discoloration of permanent teeth d. psuedamonas colitis c.<br>a patient is preparing for colon surgery and will be receiving neomycin tablets during the day before surgery. he asks the nurse why he needs to take the medicine before he even has surgery. what is the best response?a. this medicine helps clear out your bowels before surgery b. it helps to reduce the number of bacteria in your intestines c. it is given to sterilize the bowels d. it is given to prevent an infection after surgery b. Neomycin can act as an enema for patients receiving colon surgery<br>what is a common adverse effect that occurs when vancomycin is infused too quickly? red man syndrome<br>what is the method of action of quinolones? interruption of bacterial DNA replication resulting in cell death (bactericidal)<br>after an infusion of Coly-Mycin, the nurse will report to the prescriber if the patient complains of which adverse effects?a. numbness b. vertigo c. upset stomach d. insomnia e. dizziness a,b,e<br>the nurse is reviewing the list of medications for a patient who will be starting antibiotic therapy with an aminoglycoside. which medications may present a possible interaction?a. metoprolol, a beta blocker b. Furosemide, a loop diuretic c. warfarin, an oral anticoagulant d. Vancomycin, an antibiotice. Levothyroxine, a thyroid hormone b,c,d<br>Enfuvirtide (Fuzeon) MOA -Fusion Inhibitor -Blocks the fusion of HIV to CD4 receptor<br>Enfivirtide indications HIV<br>Enfuvirtide (Fuzeon) adverse effects Injection-site reactions, pneumonia, and hypersensitivity reactions<br>Enfuvirtide (Fuzeon) contraindications children &lt;6 yrs<br>Enfuvirtide (Fuzeon) nursing implications monitor viral load and assess for signs of pneumonia<br>Antivirals: Ribavirin (Virazole) MOA inhibit viral DNA and RNA synthesis<br>Antivirals: Ribavirin (Virazole) indications severe lower respiratory tract infections and HEP C<br>Antivirals: Ribavirin (Virazole) adverse effects anemia, rash, dizziness, hypotension<br>Antivirals: Ribavirin (Virazole) contraindications mechanical ventilation, pregnancy<br>Antivirals: Ribavirin (Virazole) nursing implications assess for neurological changes and may cause MI<br>Antivirals: Sofosbuvir (Sovaldi) MOA inhibits replication<br>Antivirals: Sofosbuvir (Sovaldi) indications HEP C<br>Antivirals: Sofosbuvir (Sovaldi) adverse effects GI upset, fatigue, headache, insomnia, itching<br>Antivirals: Sofosbuvir (Sovaldi) contraindications bradycardia, beta blockers, liver disease<br>A patient with HIV infection is seen in the clinic. The nurse notes the patient is experiencing weight loss, chronic diarrhea, fever, and dropping CD4 counts. The nurse anticipates the patient is in which stage of HIV infection?a. stage Ib. Stage IIc. Stage III d. Stage IV c. stage III<br>A patient with active HIV has been taking zidovudine (Retrovir). Which potential adverse effect may limit the length of time this medication can be taken?A.Lactic acidosisB.Bone marrow suppressionC.HepatomegalyFatigue b. bone marrow suppression<br>Antifungals: Griseofulvin MOA disrupts cell division and inhibits fungal cell mitosis *not commonly used anymore<br>Antifungals: Amphotericin B MOA binds to sterols in cell membrane lining resulting in cell death<br>Antifungals: Amphotericin B indications candidiasis<br>Antifungals: Amphotericin B adverse effects increase liver enzymes, neurological changes, GI upset, nephrotoxicity<br>Antifungals: Amphotericin B contraindications breast feeding<br>Antifungals: Amphotericin B nursing implications monitor vitals every 30 minutes for the first 2-4 hours after administration<br>A patient is diagnosed with onychomycosis. The nurse anticipates use of which medication for the treatment of this condition?A. terbinafine (Laminal)B. voriconazole (Vfend)C.fluconazole (Diflucan)D.amphotericin B (Amphocin, Fungizone) A.<br>Antifungals: Fluconazole (Diflucan) MOA alters cell metabolism resulting in fungal death<br>Antifungals: Fluconazole (Diflucan) adverse effects Nausea, vomiting, diarrhea, stomach pain, increased liver enzymes<br>Antifungals: Fluconazole (Diflucan) indications candidiasis of mouth or vagina; prophylactic for bone marrow transplant<br>Antifungals: Fluconazole (Diflucan) contraindications liver or renal failure<br>Antifungals: Fluconazole (Diflucan) nursing implications assess for rash or systemic infection<br>Antifungals Nystatin (Mycostatin) MOA binds to sterols in the fungal cell lining, results in death of cell<br>Antifungals Nystatin (Mycostatin) indications candidiasis of oral cavity<br>Antifungals Nystatin (Mycostatin) adverse effects SJS and GI upset<br>Antifungals Nystatin (Mycostatin) nursing implications assess oral membranes before, during, and after for irritation<br>A patient is taking nystatin (Mycostatin) in an oral troche form for oral candidiasis. Which instruction is correct?A.Allow the troche to dissolve slowly in the mouth.B.Swish the medication in the mouth and then swallow it.C.Chew the troche thoroughly to activate the medication.D.Swallow the troche whole without chewing. A.<br>A patient has developed an aspergillosis infection. Which tissue does the aspergillosis affect?A.SkinB.NailsC.BloodD. Lungs D. lungs<br>A patient is receiving amphotericin B lipid complex. The nurse knows that an advantage of the lipid formulations of this drug is that they:A.have a lower cost.B.can be administered quickly.C.take longer to be absorbed.cause fewer adverse effects. D.<br>Fifteen minutes after an infusion of amphotericin B was started, the patient begins to complain of fever, chills, muscle pain, and nausea. His heart rate has increased slightly, but his blood pressure is down to 100\/68 mm Hg. What is the nurse&#8217;s priority?A.Notify the prescriber immediately.B.Recognize an impending anaphylactic reaction and stop the infusion.C.Assess for other symptoms of this expected infusion-related reaction.D.Slow the infusion to reduce these adverse effects. c.<br>what is a neoplasm? mass of cells, tumor<br>lymphomas and leukemias are also known as circulating tumors<br>cell cycle nonspecific drugs cytotoxic at many different stages<br>cell cycle specific drugs cytotoxic at a specific stage<br>chemotherapy is harmful to all rapidly growing cells including cancer cells and normal human cells<br>antineoplastic drugs drugs used to treat cancer<br>folate antagonists: Pemetrexed (Alimta) MOA disrupts folate metabolism<br>folate antagonists: Pemetrexed (Alimta) indications malignant tumor<br>folate antagonists: Pemetrexed (Alimta) adverse effects pharyngitis, constipation, nausea, rash, infection<br>folate antagonists: Pemetrexed (Alimta) nursing implications monitor for bone marrow suppression<br>folate antagonists: Pralatrexate indication T cell lymphoma<br>folate antagonists: Pralatrexate MOA disrupts folate metabolism<br>folate antagonists: Pralatrexate adverse effects thrombocytopenia, neutropenia, sepsis<br>folate antagonists: Pralatrexate nursing implications monitor for bone marrow suppression<br>purine antagonists: fludarabine (F-AMP) MOA inhibits DNA synthesis<br>purine antagonists: fludarabine (F-AMP) indications B cell leukemia<br>purine antagonists: fludarabine (F-AMP) adverse effects neurotoxicity, GI upset, leukopenia, thrombocytopenia<br>purine antagonists: fludarabine (F-AMP) contraindications hypersensitivity and renal impairment<br>purine antagonists: fludarabine (F-AMP) nursing implications monitor for visual changes, weakness, and confusion<br>Pyrimidine antagonists: fluorouracil (5-FU) MOA inhibit DNA and RNA synthesis<br>Pyrimidine antagonists: fluorouracil (5-FU) indications many types of cancers<br>Pyrimidine antagonists: fluorouracil (5-FU) adverse effects alopecia, anemia, photosensitivity, thrombocytopenia<br>Pyrimidine antagonists: fluorouracil (5-FU) contraindications bone marrow decreased<br>Pyrimidine antagonists: fluorouracil (5-FU) nursing implications IV site inflammation, vitals monitored, signs of infection<br>What are mitotic inhibitors? Drugs that kill cells as the process of mitosis begins<br>Extravasation leakage from a vessel into the tissue<br>mitotic inhibitors adverse effects hair loss, nausea\/vomiting, liver, kidney, and lung toxicity, and extravasation<br>mitotic inhibitors indications non small cell lung cancer, testicular, breast, ovarian, kaposi&#8217;s, and acute leukemia cancers<br>mitotic inhibitors nursing implications monitor for effects on tissues<br>mitotic inhibitors MOA can work in various phases of the cell cycle<br>what are Alkaloid Topoisomerase II inhibitors used for? small cell cancer and testicular cancer<br>Alkaloid Topoisomerase II inhibitors implications remember all cells are affected ; monitor for effects on these tissues or complications ; monitor for complications<br>The nurse is caring for a patient who received chemotherapy 24 hours ago. The patient&#8217;s white blood cell count is 4,400 mcL. Which symptom, if experienced by the patient, should the nurse report to the prescriber immediately?A.FatigueB.DiarrheaC.FeverNausea and vomiting C. this is a sign of early infection; normal WBC count is 4500 to 10,000 mcL<br>When working with a patient who is neutropenic, the nurse identifies which as the most effective measure to prevent the patient from developing an infection?A.Administer prophylactic antibiotics.B.Stop administration of the chemotherapeutic drug.C.Perform hand hygiene.D.Vaccinate the patient to prevent bacterial infection. c. risk for infection is a serious adverse side effect that requires close attention. standard precautions can help quell the spread of pathogens.<br>Alkylating drugs MOA prevent cancer cells from reproducing<br>Alkylating drugs indications various types of cancer<br>Alkylating drugs adverse effects dose limiting adverse effects, alopecia, nephrotoxicity, peripheral neuropathy, ototoxicity, extravasation<br>Alkylating drug examples Cisplatin (Platinol), Cyclophosphamide (Cytoxan), and Mechlorethamine (nitrogen mustard)<br>what are cytotoxic antibiotics natural substances produced by streptomyces<br>cytotoxic antibiotics MOA CCNS drugs, blockage of DNA synthesis<br>cytotoxic antibiotics indications used in combo with chemotherapy regimens ; solid tumors<br>cytotoxic antibiotics adverse effects bone marrow suppression, hair loss, nausea and vomiting, heart failure, acute left ventricular failure, pulmonary fibrosis, liver, kidney, and cardiovascular toxicities<br>Hematopoetics: Filgrastim (Neupogen) MOA binds to and stimulates immature neutrophils<br>Hematopoetics: Filgrastim (Neupogen) indications prevents infection<br>Hematopoetics: Filgrastim (Neupogen) adverse effects acute respiratory distress, bone pain<br>Hematopoetics: Filgrastim (Neupogen) contraindications hypersensitivity<br>Hematopoetics: Sargramostim (Leukine) MOA acts on the bone marrow to increase production of WBC<br>Hematopoetics: Sargramostim (Leukine) indications bone marrow transplant, non Hodgkin&#8217;s lymphoma<br>Hematopoetics: Sargramostim (Leukine) adverse effects bone pain, itching, pain<br>Hematopoetics: Sargramostim (Leukine) contraindications newborns<br>Hematopoetics: Sargramostim (Leukine) nursing implications assess for sins of infection<br>what do hematopoietic drugs do? decrease the duration of chemotherapy and allow for higher doses of chemo<br>Interferons indications leukemia, AIDS, viral infections, MS<br>Interferons MoA suppresses immune response<br>Interferons adverse effects flulike symptoms, dose limiting effect, dizziness, anorexia, nausea\/vomiting, diarrhea<br>&#8220;Monoclonal Antibodies (&#8220;&#8221;mab&#8221;&#8221;) contraindications&#8221; very few<br>monoclonal antibodies adverse effects flulike symptoms<br>interleukins * proteins that stimulate the growth of B and T lymphocytes<br>capillary leak syndrome result in massive fluid retention due to severe toxicity of aldesleukin therapy<br>lymphokine activated killer cells recognize and destroy ONLY cancer cells and ignore normal cells<br>interleukins example aldesleukin<br>Aldesleukin indications metastatic cell carcinoma and melanoma; HIV and AIDS<br>what types of drugs are typically used to treat Rheumatoid Arthritis? NSAIDs and DMARDs<br>Methotrexate MOA folic acid antagonist<br>Methotrexate adverse effects Renal toxicity and drowsiness, bone marrow suppression<br>Methotrexate indications rheumatoid arthritis<br>Methotrexate contraindications thrombocytopenia, anemia, leukopenia, concurrent admin of hepatotoxic drugs &amp; hematopoietic suppressants, alcoholism, lactation, immunosuppressed pts<br>Methotrexate Nursing Implications takes 3-6 weeks for onset of anti rheumatic action<br>A patient who had a kidney transplant is receiving cyclosporine orally in maintenance doses. What action would decrease the potency of this drug?A.Taking it with orange juiceB.Taking it with milkC.Using a Styrofoam container to administer the drugD.Mixing it with chocolate milk c. styrofoam<br>Which oral fluid the patient requests with med administration would be most concerning to the nurse for a patient taking cyclosporine?A.WaterB.MilkC.Grapefruit juiceD.Apple juice c. grapefruit juice<br>A male patient who received a kidney transplant 6 months ago is taking cyclosporine. The patient tells the nurse that he has started to take several herbal preparations. Which does not pose a possible problem for the patient?A.St. John&#8217;s wortB.GinkgoC.Cat&#8217;s clawD.Echinacea b. ginkgo<br>humoral immunity is mediated by B lymphocyte cells<br>cellular immunity is mediated by T lymphocyte cells<br>Immunosuppressants: Azathioprine MOA prevents transplant rejection<br>Immunosuppressants: Azathioprine (Imuran) indications RA, MS, psoriasis, Crohn&#8217;s Disease, transplant maintenance<br>Immunosuppressants: Azathioprine adverse effects leukopenia, anemia, thrombocytopenia<br>Immunosuppressants: Azathioprine contraindications Pregnancy or infection<br>Immunosuppressants: Azathioprine nursing implications assess for infection; monitor for toxicity<br>Immunosuppressants: Cyclosporines (sandimmune) MOA inhibit normal immune response<br>Immunosuppressants: Cyclosporines (sandimmune) indications prevent organ rejection<br>Immunosuppressants: Cyclosporines (sandimmune) adverse effects renal impairment, increased risk of fatal infection, liver injury, seizures<br>Immunosuppressants: Cyclosporines (sandimmune) contraindications breastfeeding, hypersensitivity<br>Immunosuppressants: Cyclosporines (sandimmune) nursing implications no styrofoam cups, black box warning<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Exam 1: NR293 \/ NR 293 (Latest Update 2024\/2025) Pharmacology Review| Complete Guide with Questions and Verified Answers| 100% Correct -Chamberlain Exam 1: NR293 \/ NR 293 (Latest Update2024\/2025) Pharmacology Review| CompleteGuide with Questions and Verified Answers|100% Correct -ChamberlainQ: PharmacotherapeuticsAnswer:treatment of conditionsQ: enteral routeAnswer:through the GI tractQ: parenteral tractAnswer:outside the GI tractQ: how is medication [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[25],"tags":[],"class_list":["post-132075","post","type-post","status-publish","format-standard","hentry","category-exams-certification"],"_links":{"self":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts\/132075","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/comments?post=132075"}],"version-history":[{"count":0,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts\/132075\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/media?parent=132075"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/categories?post=132075"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/tags?post=132075"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}