A nurse is administering filgrastim, a bone marrow stimulant, to a client who has leukemia and is receiving chemotherapy that causes neutropenia. The nurse should monitor the client for which of the following adverse effects of filgrastim?<\/p>\n\n\n\n
A.
Hypertension and headache<\/p>\n\n\n\n
B.
Diarrhea and abdominal pain<\/p>\n\n\n\n
C.
Fever and flulike symptoms<\/p>\n\n\n\n
D.
Bleeding and bruising<\/p>\n\n\n\n
The Correct Answer and Explanation is:<\/mark><\/strong><\/p>\n\n\n\n The correct answer is C. Fever and flulike symptoms<\/strong>.<\/p>\n\n\n\n Filgrastim is a recombinant human granulocyte colony-stimulating factor (G-CSF) used primarily to stimulate the production of neutrophils (white blood cells) in patients undergoing chemotherapy. Chemotherapy often leads to neutropenia, a condition characterized by low neutrophil counts, increasing the risk of infections. Filgrastim helps to mitigate this risk by promoting the proliferation and differentiation of neutrophil precursors in the bone marrow.<\/p>\n\n\n\n While filgrastim is effective in increasing neutrophil counts, it can also lead to several adverse effects. One of the most common side effects reported by patients is flu-like symptoms, which can include fever, chills, fatigue, and myalgia (muscle pain). These symptoms occur as a result of the mobilization of neutrophils and their subsequent activity in the body, as the immune system becomes more responsive due to increased neutrophil levels.<\/p>\n\n\n\n Monitoring for fever and flu-like symptoms is essential for nurses administering filgrastim. Patients may also experience mild pain at the injection site, which is generally self-limiting. Other adverse effects, though less common, include splenomegaly (enlargement of the spleen) and bone pain due to increased bone marrow activity.<\/p>\n\n\n\n In contrast, the other options listed are less directly associated with filgrastim administration. Hypertension and headache (Option A) are not typical side effects. Diarrhea and abdominal pain (Option B) may occur but are not common. Bleeding and bruising (Option D) could be attributed to thrombocytopenia (low platelet count), which is not a direct effect of filgrastim. Thus, while nurses should monitor for various potential side effects, the most significant and common adverse effect associated with filgrastim is fever and flu-like symptoms.<\/p>\n","protected":false},"excerpt":{"rendered":" A nurse is administering filgrastim, a bone marrow stimulant, to a client who has leukemia and is receiving chemotherapy that causes neutropenia. The nurse should monitor the client for which of the following adverse effects of filgrastim? A.Hypertension and headache B.Diarrhea and abdominal pain C.Fever and flulike symptoms D.Bleeding and bruising The Correct Answer and […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[25],"tags":[],"class_list":["post-140329","post","type-post","status-publish","format-standard","hentry","category-exams-certification"],"_links":{"self":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts\/140329","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/comments?post=140329"}],"version-history":[{"count":0,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts\/140329\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/media?parent=140329"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/categories?post=140329"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/tags?post=140329"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}