Which of the following statements best describes the involvement of the immune system in psoriasis etiology?
A.
Immune system suppresses inflammation and skin cell proliferation<\/p>\n\n\n\n
B.
Immune system responds normally to environmental triggers<\/p>\n\n\n\n
C.
Immune system becomes overactive, leading to inflammation and excessive skin cell growth<\/p>\n\n\n\n
D.
Immune system functions independently of psoriasis development<\/p>\n\n\n\n
The correct answer and Explanation is :<\/strong><\/mark><\/p>\n\n\n\n The correct answer is C. Immune system becomes overactive, leading to inflammation and excessive skin cell growth.<\/strong><\/p>\n\n\n\n Psoriasis is a chronic autoimmune condition where the immune system mistakenly identifies normal skin cells as harmful. In a healthy immune system, T cells (a type of white blood cell) help defend the body against infections by attacking foreign invaders like bacteria and viruses. However, in psoriasis, these T cells become overactive and target healthy skin cells. This immune system malfunction is a key factor in the etiology of the disease.<\/p>\n\n\n\n The overactivation of T cells leads to an abnormal immune response, releasing inflammatory signals, including cytokines such as TNF-alpha, interleukins (IL-17, IL-23), and interferons. These cytokines create an inflammatory environment in the skin. This inflammation then accelerates the production of skin cells (keratinocytes), causing them to proliferate at an abnormally high rate. In psoriasis, the skin cells mature and rise to the surface of the skin in just a few days, instead of the normal cycle of about a month. The excessive buildup of these skin cells leads to the formation of thick, scaly patches on the skin, characteristic of psoriasis.<\/p>\n\n\n\n This immune-driven process explains why psoriasis is often treated with medications that suppress the immune system or specifically target the cytokines involved in inflammation. Biologic drugs, for example, target specific molecules like TNF-alpha or IL-17 to reduce inflammation and control the symptoms.<\/p>\n\n\n\n Thus, psoriasis is not simply a skin condition but a systemic inflammatory disorder with immune system dysregulation at its core.<\/p>\n","protected":false},"excerpt":{"rendered":" Which of the following statements best describes the involvement of the immune system in psoriasis etiology?A.Immune system suppresses inflammation and skin cell proliferation B.Immune system responds normally to environmental triggers C.Immune system becomes overactive, leading to inflammation and excessive skin cell growth D.Immune system functions independently of psoriasis development The correct answer and Explanation is […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[25],"tags":[],"class_list":["post-141113","post","type-post","status-publish","format-standard","hentry","category-exams-certification"],"_links":{"self":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts\/141113","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/comments?post=141113"}],"version-history":[{"count":0,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts\/141113\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/media?parent=141113"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/categories?post=141113"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/tags?post=141113"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}Explanation:<\/h3>\n\n\n\n