A mother with sickle anemia asks the nurse why her child’s hemoglobin was normal at birth and now the child has the S hemoglobin (sickle cell). Which of the following is an appropriate response from the nurse?<\/p>\n\n\n\n
A. The red bone marrow does not begin to produce hemoglobin (S)
B. The placenta bars passage of the hemoglobin S from the mother
C. Antibodies transmitted from you to the fetus provided the newborn with temporary immunity.
D. At birth, a newborn has a high concentration of fetal hemoglobin in the blood, which over time, have been replaced by these abnormal S hemoglobin cells<\/p>\n\n\n\n
The Correct answer and Explanation is:<\/mark><\/strong><\/p>\n\n\n\n The correct answer is D. At birth, a newborn has a high concentration of fetal hemoglobin in the blood, which over time has been replaced by these abnormal S hemoglobin cells.<\/strong><\/p>\n\n\n\n At birth, infants possess a significant amount of fetal hemoglobin (HbF), which is the primary form of hemoglobin present during fetal development. Fetal hemoglobin has a higher affinity for oxygen than adult hemoglobin (HbA) and plays a crucial role in ensuring adequate oxygen transfer from the mother to the fetus during pregnancy. This HbF is composed of two alpha and two gamma chains, differentiating it from the adult hemoglobin which consists of two alpha and two beta chains.<\/p>\n\n\n\n In children who inherit sickle cell disease (SCD), they typically receive one sickle cell gene (hemoglobin S) from one parent and an abnormal gene from the other, or two sickle cell genes (SS) from both parents. While newborns may initially show normal hemoglobin levels due to the predominance of HbF, over time\u2014often within the first few months to a few years\u2014the levels of HbF gradually decrease, and hemoglobin S production increases. This shift occurs as the infant\u2019s body begins to produce adult-type hemoglobin.<\/p>\n\n\n\n As a result, the presence of sickle hemoglobin becomes more pronounced. Sickle cell hemoglobin is associated with several complications, including vaso-occlusive crises, pain episodes, and increased risk of infections due to spleen dysfunction. Understanding this process is crucial for parents and caregivers, as it emphasizes the dynamic nature of hemoglobin types in the early stages of life and the transition from fetal to adult hemoglobin. It also highlights the importance of regular medical follow-ups and proactive management to mitigate potential complications associated with sickle cell disease.<\/p>\n","protected":false},"excerpt":{"rendered":" A mother with sickle anemia asks the nurse why her child’s hemoglobin was normal at birth and now the child has the S hemoglobin (sickle cell). Which of the following is an appropriate response from the nurse? A. The red bone marrow does not begin to produce hemoglobin (S)B. The placenta bars passage of the […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[25],"tags":[],"class_list":["post-143220","post","type-post","status-publish","format-standard","hentry","category-exams-certification"],"_links":{"self":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts\/143220","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/comments?post=143220"}],"version-history":[{"count":0,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts\/143220\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/media?parent=143220"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/categories?post=143220"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/tags?post=143220"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}Explanation:<\/h3>\n\n\n\n