{"id":151987,"date":"2024-10-10T15:40:58","date_gmt":"2024-10-10T15:40:58","guid":{"rendered":"https:\/\/learnexams.com\/blog\/?p=151987"},"modified":"2024-10-10T15:41:00","modified_gmt":"2024-10-10T15:41:00","slug":"select-the-two-components-of-an-active-cdk","status":"publish","type":"post","link":"https:\/\/www.learnexams.com\/blog\/2024\/10\/10\/select-the-two-components-of-an-active-cdk\/","title":{"rendered":"Select the two components of an active Cdk"},"content":{"rendered":"\n<p>Select the two components of an active Cdk.<br>MPF cofactor<br>A protein kinase<br>A short RNA molecule<br>Cyclin<\/p>\n\n\n\n<p><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-ast-global-color-6-color\"><strong>The Correct Answer and Explanation is :<\/strong><\/mark><\/p>\n\n\n\n<p>The two components of an active cyclin-dependent kinase (Cdk) are <strong>a protein kinase<\/strong> and <strong>cyclin<\/strong>.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Explanation<\/h3>\n\n\n\n<p>Cyclin-dependent kinases (Cdks) are essential regulatory proteins that play a critical role in controlling the cell cycle. They are a part of a larger family of serine\/threonine kinases, which means they phosphorylate specific serine or threonine residues in target proteins, thereby altering their activity, stability, or localization. However, Cdks are not active on their own; their activity is regulated by the binding of cyclins.<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong>A Protein Kinase<\/strong>: At their core, Cdks are protein kinases. This means they have the enzymatic ability to transfer a phosphate group from ATP to specific substrates (proteins), which can activate or deactivate these proteins, influencing various cellular processes. The kinase activity is fundamental for driving key events in the cell cycle, such as DNA replication and cell division. The specificity of the Cdk for its substrates is determined by the interaction with cyclins.<\/li>\n\n\n\n<li><strong>Cyclin<\/strong>: Cyclins are regulatory proteins that bind to Cdks, forming an active Cdk-cyclin complex. The levels of cyclins fluctuate throughout the cell cycle, ensuring that Cdks are active only at specific times. For example, the presence of cyclin B activates Cdk1, which is essential for the transition from the G2 phase to mitosis. The binding of cyclin induces a conformational change in the Cdk, allowing it to become enzymatically active and phosphorylate target substrates. The specific cyclin present will dictate the Cdk&#8217;s function at various checkpoints of the cell cycle.<\/li>\n<\/ol>\n\n\n\n<p>In summary, an active Cdk consists of a protein kinase (the Cdk itself) and a cyclin, which is crucial for the proper regulation of the cell cycle and cellular processes that underpin growth and division.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Select the two components of an active Cdk.MPF cofactorA protein kinaseA short RNA moleculeCyclin The Correct Answer and Explanation is : The two components of an active cyclin-dependent kinase (Cdk) are a protein kinase and cyclin. Explanation Cyclin-dependent kinases (Cdks) are essential regulatory proteins that play a critical role in controlling the cell cycle. They [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[25],"tags":[],"class_list":["post-151987","post","type-post","status-publish","format-standard","hentry","category-exams-certification"],"_links":{"self":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts\/151987","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/comments?post=151987"}],"version-history":[{"count":0,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts\/151987\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/media?parent=151987"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/categories?post=151987"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/tags?post=151987"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}