{"id":194591,"date":"2025-02-24T09:43:12","date_gmt":"2025-02-24T09:43:12","guid":{"rendered":"https:\/\/learnexams.com\/blog\/?p=194591"},"modified":"2025-02-24T09:43:14","modified_gmt":"2025-02-24T09:43:14","slug":"ammonia-nh3-has-pka-36-and-acetone-has-pka-19","status":"publish","type":"post","link":"https:\/\/www.learnexams.com\/blog\/2025\/02\/24\/ammonia-nh3-has-pka-36-and-acetone-has-pka-19\/","title":{"rendered":"Ammonia, NH3, has pKa = 36 and acetone has pKa 19"},"content":{"rendered":"\n<p>Ammonia, NH3, has pKa = 36 and acetone has pKa 19. <\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" src=\"https:\/\/learnexams.com\/blog\/wp-content\/uploads\/2025\/02\/image-1377.png\" alt=\"\" class=\"wp-image-194592\"\/><\/figure>\n\n\n\n<p><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-ast-global-color-6-color\"><strong>The Correct Answer and Explanation is :<\/strong><\/mark><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Reaction Feasibility Analysis:<\/strong><\/h3>\n\n\n\n<p>The reaction likely involves <strong>ammonia (NH\u2083) acting as a base<\/strong> and <strong>acetone acting as an acid<\/strong> by donating a proton from its \u03b1-carbon (adjacent to the carbonyl group).<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>pKa of ammonia (NH\u2083) = 36<\/strong><\/li>\n\n\n\n<li><strong>pKa of acetone (CH\u2083COCH\u2083) = 19<\/strong><\/li>\n<\/ul>\n\n\n\n<p>The key principle in acid-base reactions is that <strong>a stronger acid (lower pKa) donates a proton to a stronger base (higher pKa of its conjugate acid)<\/strong>.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Will the Reaction Occur?<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li>The pKa of acetone (19) is significantly lower than that of ammonia (36), meaning that acetone is a much stronger acid than ammonia.<\/li>\n\n\n\n<li>The conjugate base of acetone (the enolate ion) is much more stable than the conjugate base of ammonia (NH\u2082\u207b).<\/li>\n\n\n\n<li>For an acid-base reaction to proceed significantly, the equilibrium should favor the formation of the weaker acid and base.<\/li>\n\n\n\n<li>Since ammonia is a very weak base (compared to strong bases like hydroxide or alkoxide), it <strong>is not strong enough<\/strong> to deprotonate acetone effectively.<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Conclusion:<\/strong><\/h3>\n\n\n\n<p>The reaction will <strong>not<\/strong> take place because ammonia is too weak of a base to deprotonate acetone. Instead, a much stronger base such as NaOH or LDA (lithium diisopropylamide) would be required for enolate formation.<\/p>\n\n\n\n<p>Now, I&#8217;ll generate an image illustrating this reaction with explanations.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" src=\"https:\/\/learnexams.com\/blog\/wp-content\/uploads\/2025\/02\/image-1378.png\" alt=\"\" class=\"wp-image-194593\"\/><\/figure>\n\n\n\n<p>Here is the generated image illustrating why the reaction does not take place. It visually explains that ammonia is too weak of a base to deprotonate acetone due to the significant pKa difference. Let me know if you need any modifications or further clarifications!<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Ammonia, NH3, has pKa = 36 and acetone has pKa 19. The Correct Answer and Explanation is : Reaction Feasibility Analysis: The reaction likely involves ammonia (NH\u2083) acting as a base and acetone acting as an acid by donating a proton from its \u03b1-carbon (adjacent to the carbonyl group). The key principle in acid-base reactions [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[25],"tags":[],"class_list":["post-194591","post","type-post","status-publish","format-standard","hentry","category-exams-certification"],"_links":{"self":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts\/194591","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/comments?post=194591"}],"version-history":[{"count":0,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts\/194591\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/media?parent=194591"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/categories?post=194591"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/tags?post=194591"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}