The conjugate base of the active ingredient in aspirin, acetylsalicylic acid (C\u2089H\u2088O\u2084)<\/strong>, is formed when the acid loses a proton (H\u207a) from its carboxyl group (-COOH). The formula of the conjugate base<\/strong> is C\u2089H\u2087O\u2084\u207b<\/strong>.<\/p>\n\n\n\n Acetylsalicylic acid contains both an ester group (-COOCH\u2083) and a carboxyl group (-COOH). The carboxyl group is responsible for its acidic properties. When acetylsalicylic acid dissociates in water, the hydrogen ion (H\u207a) from the carboxyl group is released, resulting in the formation of the conjugate base.<\/p>\n\n\n\n Thus, the conjugate base of acetylsalicylic acid is C\u2089H\u2087O\u2084\u207b<\/strong>, and the process involves the deprotonation of the carboxyl group to stabilize the negative charge.<\/p>\n\n\n\n Write the formula of the conjugate base of the active ingredient in aspirin, acetylsalicylic acid, C9H8O4 The correct answer and explanation is : The conjugate base of the active ingredient in aspirin, acetylsalicylic acid (C\u2089H\u2088O\u2084), is formed when the acid loses a proton (H\u207a) from its carboxyl group (-COOH). The formula of the conjugate base […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[25],"tags":[],"class_list":["post-197899","post","type-post","status-publish","format-standard","hentry","category-exams-certification"],"_links":{"self":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts\/197899","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/comments?post=197899"}],"version-history":[{"count":0,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts\/197899\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/media?parent=197899"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/categories?post=197899"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/tags?post=197899"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}Explanation:<\/h3>\n\n\n\n
\n
Acetylsalicylic acid has the chemical structure of a benzene ring (C\u2086H\u2085) attached to a carboxyl group (-COOH) and an ester group (-COOCH\u2083). The carboxyl group is acidic, and it is this group that loses a proton during dissociation.<\/li>\n\n\n\n
In aqueous solutions, acetylsalicylic acid can lose a proton from the carboxyl group as follows:
[
\\text{C\u2089H\u2088O\u2084} \\rightarrow \\text{C\u2089H\u2087O\u2084}\u207b + \\text{H}\u207a
]
When the proton (H\u207a) is lost, the negative charge is delocalized over the oxygen atoms in the carboxylate group, stabilizing the conjugate base. This gives the conjugate base C\u2089H\u2087O\u2084\u207b<\/strong>.<\/li>\n\n\n\n
The conjugate base, C\u2089H\u2087O\u2084\u207b<\/strong>, retains the ester group (-COOCH\u2083) and the benzene ring but now has one fewer hydrogen atom, resulting in a negative charge on one of the oxygen atoms in the carboxylate group. This form is less acidic than acetylsalicylic acid itself because the conjugate base is a weaker acid compared to the neutral form.<\/li>\n<\/ol>\n\n\n\n![\"\"](\"https:\/\/learnexams.com\/blog\/wp-content\/uploads\/2025\/03\/image-574.png\")
<\/figure>\n","protected":false},"excerpt":{"rendered":"