{"id":204832,"date":"2025-03-22T16:23:49","date_gmt":"2025-03-22T16:23:49","guid":{"rendered":"https:\/\/learnexams.com\/blog\/?p=204832"},"modified":"2025-03-22T16:23:51","modified_gmt":"2025-03-22T16:23:51","slug":"match-each-of-the-following-classes-of-eicosanoids-with-its-function","status":"publish","type":"post","link":"https:\/\/www.learnexams.com\/blog\/2025\/03\/22\/match-each-of-the-following-classes-of-eicosanoids-with-its-function\/","title":{"rendered":"Match each of the following classes of eicosanoids with its function"},"content":{"rendered":"\n<p>Match each of the following classes of eicosanoids with its function:<\/p>\n\n\n\n<p>Leukotrienes: Mediate allergic and inflammatory reactions<br>Prostacyclin: Inhibit(s) blood clotting and vasoconstriction<br>Prostaglandins: Relax and\/or contract smooth muscle<br>Thromboxanes: Stimulate(s) vasoconstriction and clotting<\/p>\n\n\n\n<p><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-ast-global-color-6-color\"><strong>The correct answer and explanation is :<\/strong><\/mark><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Correct Matching of Eicosanoids and Their Functions:<\/h3>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong>Leukotrienes<\/strong> \u2192 Mediate allergic and inflammatory reactions<\/li>\n\n\n\n<li><strong>Prostacyclin<\/strong> \u2192 Inhibit(s) blood clotting and vasoconstriction<\/li>\n\n\n\n<li><strong>Prostaglandins<\/strong> \u2192 Relax and\/or contract smooth muscle<\/li>\n\n\n\n<li><strong>Thromboxanes<\/strong> \u2192 Stimulate(s) vasoconstriction and clotting<\/li>\n<\/ol>\n\n\n\n<h3 class=\"wp-block-heading\">Explanation:<\/h3>\n\n\n\n<p>Eicosanoids are lipid-derived signaling molecules synthesized from arachidonic acid and play crucial roles in physiological and pathological processes. They include leukotrienes, prostacyclins, prostaglandins, and thromboxanes, each with distinct biological effects.<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong>Leukotrienes<\/strong>: These molecules are primarily produced by leukocytes and are involved in immune responses, particularly in inflammation and allergic reactions. They contribute to bronchoconstriction in asthma, increased vascular permeability, and chemotaxis (the attraction of immune cells to sites of infection or injury).<\/li>\n\n\n\n<li><strong>Prostacyclin (PGI\u2082)<\/strong>: This eicosanoid is produced by endothelial cells and plays a vital role in cardiovascular homeostasis. It inhibits platelet aggregation (preventing clot formation) and promotes vasodilation, thereby reducing blood pressure and maintaining smooth blood flow.<\/li>\n\n\n\n<li><strong>Prostaglandins (PGs)<\/strong>: These compounds have diverse effects depending on the specific type (PGE\u2082, PGF\u2082\u03b1, etc.). Some prostaglandins cause smooth muscle relaxation (e.g., PGE\u2082 in the vasculature and bronchi), while others induce contraction (e.g., PGF\u2082\u03b1 in the uterus during labor). They also regulate inflammation, fever, and pain.<\/li>\n\n\n\n<li><strong>Thromboxanes (TXA\u2082)<\/strong>: Produced mainly by platelets, thromboxanes have the opposite effect of prostacyclins. They promote platelet aggregation, vasoconstriction, and blood clot formation, which is essential for stopping bleeding but can also contribute to conditions like thrombosis if excessively activated.<\/li>\n<\/ol>\n\n\n\n<p>Understanding eicosanoids is critical in pharmacology and medicine, as drugs like aspirin and NSAIDs inhibit their synthesis to reduce inflammation, pain, and clotting risks.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Match each of the following classes of eicosanoids with its function: Leukotrienes: Mediate allergic and inflammatory reactionsProstacyclin: Inhibit(s) blood clotting and vasoconstrictionProstaglandins: Relax and\/or contract smooth muscleThromboxanes: Stimulate(s) vasoconstriction and clotting The correct answer and explanation is : Correct Matching of Eicosanoids and Their Functions: Explanation: Eicosanoids are lipid-derived signaling molecules synthesized from arachidonic acid [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center 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