{"id":207009,"date":"2025-04-18T08:40:18","date_gmt":"2025-04-18T08:40:18","guid":{"rendered":"https:\/\/learnexams.com\/blog\/?p=207009"},"modified":"2025-04-18T08:40:20","modified_gmt":"2025-04-18T08:40:20","slug":"the-function-of-ef-tu-during-protein-synthesis-is-to","status":"publish","type":"post","link":"https:\/\/www.learnexams.com\/blog\/2025\/04\/18\/the-function-of-ef-tu-during-protein-synthesis-is-to\/","title":{"rendered":"The function of EF-Tu during protein synthesis is to"},"content":{"rendered":"\n<p>The function of EF-Tu during protein synthesis is to: <\/p>\n\n\n\n<p>A deliver aminoacyl-tRNAs to the A site <\/p>\n\n\n\n<p>B assist GTP binding to EF-G<\/p>\n\n\n\n<p> C assist ATP binding to EF-G <\/p>\n\n\n\n<p>D deliver Met-tRNA Met to the P site<\/p>\n\n\n\n<p> E assist GDP release from EF-G<\/p>\n\n\n\n<p><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-ast-global-color-6-color\"><strong>The correct answer and explanation is :<\/strong><\/mark><\/p>\n\n\n\n<p><strong>Correct Answer: A. Deliver aminoacyl-tRNAs to the A site<\/strong><\/p>\n\n\n\n<p><strong>Explanation:<\/strong><\/p>\n\n\n\n<p>During protein synthesis in prokaryotes, elongation factor Tu (EF-Tu) plays a crucial role in the elongation phase of translation by ensuring the correct delivery of aminoacyl-tRNAs (aa-tRNAs) to the ribosome. Specifically, EF-Tu binds to GTP and forms a ternary complex with an aminoacyl-tRNA. This complex is responsible for delivering the aminoacyl-tRNA to the <strong>A site<\/strong> of the ribosome.<\/p>\n\n\n\n<p>Once the ternary complex reaches the A site, the ribosome checks the codon-anticodon interaction between the mRNA and the incoming tRNA. If the match is correct, GTP is hydrolyzed to GDP by EF-Tu. This hydrolysis induces a conformational change in EF-Tu, causing it to release the aminoacyl-tRNA, allowing the tRNA to fully enter the A site and participate in peptide bond formation.<\/p>\n\n\n\n<p>After GTP hydrolysis and release from the ribosome, EF-Tu bound to GDP is inactive. To become active again, EF-Tu requires the help of another elongation factor, EF-Ts, which acts as a guanine nucleotide exchange factor (GEF). EF-Ts facilitates the release of GDP from EF-Tu, allowing a new GTP molecule to bind and regenerate the active EF-Tu\u2022GTP complex for another round of elongation.<\/p>\n\n\n\n<p>EF-Tu&#8217;s function is critical for ensuring translational fidelity. By allowing only correctly paired codon-anticodon interactions to proceed (as incorrect pairings delay GTP hydrolysis), EF-Tu contributes to the high accuracy of protein synthesis.<\/p>\n\n\n\n<p><strong>Other options explained briefly:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>B &amp; C<\/strong>: EF-G is involved in translocation, but EF-Tu does not assist in its GTP or ATP binding.<\/li>\n\n\n\n<li><strong>D<\/strong>: Met-tRNA<sup>Met<\/sup> is delivered to the P site by initiation factors, not EF-Tu.<\/li>\n\n\n\n<li><strong>E<\/strong>: GDP release from EF-G is not facilitated by EF-Tu but is part of EF-G&#8217;s own recycling process.<\/li>\n<\/ul>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" src=\"https:\/\/learnexams.com\/blog\/wp-content\/uploads\/2025\/04\/image-129.png\" alt=\"\" class=\"wp-image-207010\"\/><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>The function of EF-Tu during protein synthesis is to: A deliver aminoacyl-tRNAs to the A site B assist GTP binding to EF-G C assist ATP binding to EF-G D deliver Met-tRNA Met to the P site E assist GDP release from EF-G The correct answer and explanation is : Correct Answer: A. Deliver aminoacyl-tRNAs to [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[25],"tags":[],"class_list":["post-207009","post","type-post","status-publish","format-standard","hentry","category-exams-certification"],"_links":{"self":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts\/207009","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/comments?post=207009"}],"version-history":[{"count":0,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts\/207009\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/media?parent=207009"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/categories?post=207009"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/tags?post=207009"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}