{"id":222351,"date":"2025-05-31T09:04:44","date_gmt":"2025-05-31T09:04:44","guid":{"rendered":"https:\/\/learnexams.com\/blog\/?p=222351"},"modified":"2025-05-31T09:04:47","modified_gmt":"2025-05-31T09:04:47","slug":"select-all-the-true-statements-regarding-glycolysis","status":"publish","type":"post","link":"https:\/\/www.learnexams.com\/blog\/2025\/05\/31\/select-all-the-true-statements-regarding-glycolysis\/","title":{"rendered":"Select ALL the TRUE statements regarding glycolysis"},"content":{"rendered":"\n<ol start=\"2\" class=\"wp-block-list\">\n<li>Select ALL the TRUE statements regarding glycolysis<\/li>\n<\/ol>\n\n\n\n<p>A.<\/p>\n\n\n\n<p>Glycolysis produces 32-34 molecules of ATP per glucose molecule<\/p>\n\n\n\n<p>B.<\/p>\n\n\n\n<p>Glycolysis occurs within the mitochondrial matrix of both prokaryotes and eukaryotes.<\/p>\n\n\n\n<p>C.<\/p>\n\n\n\n<p>During the conversion stages of 3-carbon molecules that result in forming pyruvic acid (pyruvate), NAD+ is reduced to NADH.<\/p>\n\n\n\n<p>D.<\/p>\n\n\n\n<p>The pyruvate made during glycolysis can be used either in the Krebs cycle or fermentation, and the NADH+ is used in the electron transport chain.<\/p>\n\n\n\n<p>E.<\/p>\n\n\n\n<p>Two molecules of ATP are utilized to fuel the reactions of glycolysis.<\/p>\n\n\n\n<p>F.<\/p>\n\n\n\n<p>Glycolysis is the breakdown of glucose, which is a key part of the metabolism of both aerobic and anaerobic organisms.<\/p>\n\n\n\n<p><strong><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-ast-global-color-1-color\">The Correct Answer and Explanation is:<\/mark><\/strong><\/p>\n\n\n\n<p><strong>Correct Answers: C, D, E, and F<\/strong><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Explanation <\/strong><\/h3>\n\n\n\n<p>Glycolysis is a fundamental metabolic pathway that breaks down <strong>glucose (a 6-carbon sugar)<\/strong> into <strong>two molecules of pyruvate (3-carbon compounds)<\/strong>. This process occurs in the <strong>cytoplasm<\/strong> of both <strong>prokaryotic and eukaryotic<\/strong> cells\u2014not in the mitochondrial matrix\u2014making <strong>statement B false<\/strong>.<\/p>\n\n\n\n<p><strong>Statement A is incorrect<\/strong> because glycolysis itself only produces a <strong>net gain of 2 ATP molecules<\/strong> per glucose, not 32\u201334. The larger ATP yield (about 32\u201334 ATP) comes from <strong>cellular respiration as a whole<\/strong>, including the <strong>Krebs cycle and the electron transport chain<\/strong>, but not from glycolysis alone.<\/p>\n\n\n\n<p><strong>Statement C is true<\/strong>: During glycolysis, specifically in the energy payoff phase, the 3-carbon intermediates (like glyceraldehyde-3-phosphate) are oxidized, and <strong>NAD+ is reduced to NADH<\/strong>. This is a key step, as the captured electrons will later be used in the electron transport chain (in aerobic organisms).<\/p>\n\n\n\n<p><strong>Statement D is also true<\/strong>: After glycolysis, pyruvate has two potential fates. Under <strong>aerobic conditions<\/strong>, it enters the <strong>Krebs cycle<\/strong> for further breakdown and energy extraction. Under <strong>anaerobic conditions<\/strong>, it may undergo <strong>fermentation<\/strong> (e.g., lactic acid or alcohol fermentation). Meanwhile, <strong>NADH<\/strong> produced in glycolysis can be used in the <strong>electron transport chain<\/strong> to produce more ATP, but only if oxygen is present.<\/p>\n\n\n\n<p><strong>Statement E is correct<\/strong>: Glycolysis requires an <strong>initial investment of 2 ATP molecules<\/strong> during its early steps (energy investment phase) to phosphorylate glucose and its intermediates, which helps drive the later energy-releasing reactions.<\/p>\n\n\n\n<p><strong>Statement F is correct<\/strong>: Glycolysis is <strong>central to both aerobic and anaerobic metabolism<\/strong>, making it one of the most <strong>ancient and conserved pathways<\/strong> in biology. It provides a quick supply of energy and intermediates needed for other pathways.<\/p>\n\n\n\n<p>Thus, <strong>C, D, E, and F are the true statements<\/strong>.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" src=\"https:\/\/learnexams.com\/blog\/wp-content\/uploads\/2025\/05\/learnexams-banner7-157.jpeg\" alt=\"\" class=\"wp-image-222352\"\/><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>A. Glycolysis produces 32-34 molecules of ATP per glucose molecule B. Glycolysis occurs within the mitochondrial matrix of both prokaryotes and eukaryotes. C. During the conversion stages of 3-carbon molecules that result in forming pyruvic acid (pyruvate), NAD+ is reduced to NADH. D. The pyruvate made during glycolysis can be used either in the Krebs [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[25],"tags":[],"class_list":["post-222351","post","type-post","status-publish","format-standard","hentry","category-exams-certification"],"_links":{"self":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts\/222351","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/comments?post=222351"}],"version-history":[{"count":0,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/posts\/222351\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/media?parent=222351"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/categories?post=222351"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.learnexams.com\/blog\/wp-json\/wp\/v2\/tags?post=222351"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}