1. Question
Flumazenil (Romazicon) has been ordered for a male client who has overdosed on oxazepam (Serax). Before administering the medication,Â
nurse Gina should be prepared for which common adverse effect?
o A. Seizures o B. Shivering
o C. Anxiety o D. Chest pain
Incorrect
Correct Answer: A. Seizures
Seizures are the most common serious adverse effect of usingÂ
flumazenil to reverse benzodiazepine overdose. The effect is magnified
if the client has a combined tricyclic antidepressant andÂ
benzodiazepine overdose. Benzodiazepine reversal has correlationsÂ
with seizures. Seizures may happen more frequently in patients whoÂ
have been on benzodiazepines for long-term sedation or in patientsÂ
who are showing signs of severe tricyclic antidepressant overdose. The
required dosage of Flumazenil should be measured and prepared byÂ
the practitioners to manage seizures. Flumazenil use requires cautionÂ
in patients relying on a benzodiazepine for seizure control. o Option B: Shivering is not an adverse effect of flumazenil.Â
Monitor the patient for the possible return of sedation, mostly inÂ
those who are tolerant of benzodiazepines. Patients should haveÂ
monitoring for respiratory depression, benzodiazepineÂ
withdrawal, and other residual effects of benzodiazepines for atÂ
least 2 hours. o Option C: Anxiety is a rare adverse effect for people usingÂ
flumazenil. Flumazenil has some associations with precipitation of
seizures in patients with benzodiazepine dependence with aÂ
history of seizures. Flumazenil overdose is extremely rare. ThereÂ
is no precise antidote for flumazenil toxicity. In mild to severe toxicity, symptomatic and supportive treatment should be aÂ
consideration. o Option D: An overdose of flumazenil in a patient who is not
a chronic benzodiazepine user would not be expected. ChronicÂ
benzodiazepines users may experience withdrawal with abruptÂ
discontinuation of the drug. Administration of benzodiazepines orÂ
barbiturates may be necessary for seizure control. ï‚· 2. Question
Nurse Tamara is caring for a client diagnosed with bulimia. The mostÂ
appropriate initial goal for a client diagnosed with bulimia is to:
o A. Avoid shopping for large amounts of food. o B. Control eating impulses. o C. Identify anxiety-causing situations. o D. Eat only three meals per day. Incorrect
Correct Answer: C. Identify anxiety-causing situations
Bulimic behavior is generally a maladaptive coping response to stress and underlying issues. The client must identify anxiety-causingÂ
situations that stimulate the bulimic behavior and then learn new ways
of coping with the anxiety. Bulimia nervosa is a condition that occursÂ
most commonly in adolescent females, characterized by indulgence inÂ
binge-eating, and inappropriate compensatory behaviors to preventÂ
weight gain. o Option A: Controlling shopping for large amounts of foodÂ
isn’t a goal early in treatment. It is important to educate patientsÂ
who abuse laxatives that these medications work in theÂ
gastrointestinal tract after the areas where caloric absorption has occurred primarily. It is crucial to inform patients that a period ofÂ
edema and weight gain may follow up to several weeks afterÂ
discontinuation of purging behavior. o Option B: Managing eating impulses and replacing themÂ
with adaptive coping mechanisms can be integrated into the plan
of care after initially addressing stress and underlying issues. TheÂ
primary objective of treatment is a cessation of the binging andÂ
purging behavior. Selective serotonin reuptake inhibitors such asÂ
fluoxetine, citalopram, and sertraline have shown to reduceÂ
symptoms of bulimia nervosa. Fluoxetine is the only FDAÂ
approved medication for bulimia nervosa. It appears that a higher
dose (60 mg) is significantly better than a placebo in decreasingÂ
the frequency of binge and vomiting episodes. o Option D: Eating three meals per day isn’t a realistic goalÂ
early in treatment. Patients with bulimia nervosa who purge byÂ
vomiting often brush their teeth immediately after purging, which
can accelerate dental erosion. The clinician should instruct theÂ
patients who persist in vomiting to rinse their mouths with waterÂ
or fluoride rather than brushing their teeth within 30 minutes ofÂ
each episode. Consider consulting a dentist to address dentalÂ
issues associated with vomiting. ï‚· 3. Question
A female client who’s at high risk for suicide needs close supervision.Â
To best ensure the client’s safety, Nurse Mary should:
o A. Check the client frequently at irregularÂ
intervals throughout the night. o B. Assure the client that the nurse will hold inÂ
confidence anything the client says. o C. Repeatedly discuss previous suicide attempts withÂ
the client. o D. Disregard decreased communication by the clientÂ
because this is common with suicidal clients.
Incorrect
Correct Answer: A. Check the client frequently at irregularÂ
intervals throughout the night
Checking the client frequently but at irregular intervals prevents theÂ
client from predicting when observation will take place and alteringÂ
behavior in a misleading way at these times. Once the patient isÂ
deemed to be at risk for suicide, then intervention steps must beÂ
initiated right away. The individual must not be left alone. Enlist theÂ
help of a support person while at home. The suicidal individual must be
treated in a safe and secure place. In addition, the place has to beÂ
monitored. o Option B: This may encourage the client to try toÂ
manipulate the nurse or seek attention for having a secret suicide
plan. Assessing the individual’s judgment is critical. One shouldÂ
try and determine how the individual can handle stress. Does heÂ
or she have an impairment in decision making? Does theÂ
individual know that jumping in front of a train is dangerous?Â
Reflect empathy and concern. Offer a hand to help. Provide theÂ
patient with confidence that he or she can overcome the issues. o Option C: This may reinforce suicidal ideas. Help developÂ
internal coping strategies (e.g., exercise, journaling, reading,Â
developing a hobby). Utilize the help of healthcare professionalsÂ
to follow up on therapy. Once the individual is safe as an inpatient
or outpatient, a formal treatment plan should be established. The next step is to refer all patients deemed to be at higher risk for suicide to a mental health counselor as soon as possible. EveryÂ
state has laws and procedures regarding this process which mustÂ
be incorporated into the clinical practice when addressingÂ
individuals at high suicide risk. o Option D: Decreased communication is a sign ofÂ
withdrawal that may indicate the client has decided to commitÂ
suicide; the nurse shouldn’t disregard it. In some cases,Â
assessment of the mental status may provide a clue to theÂ
individual’s potential for self-harm. Depressed patients will oftenÂ
tend to appear unclean and unkempt. The clothing may not beÂ
ironed or dirty. The risk of suicide is often high in people whoÂ
appear very anxious or depressed. The patient may exhibit a flatÂ
affect or no emotions at all. Some depressed patients mayÂ
develop hallucinations that may be telling him or her to killÂ
themselves. The majority of these hallucinations are auditory. ï‚· 4. Question
Which of the following drugs should Nurse Mary prepare to administerÂ
to a client with a toxic acetaminophen (Tylenol) level?
o A. Deferoxamine mesylate (Desferal) o B. Succimer (Chemet) o C. Flumazenil (Romazicon) o D. Acetylcysteine (Mucomyst)
Incorrect
Correct Answer: D. Acetylcysteine (Mucomyst)
The antidote for acetaminophen toxicity is acetylcysteine. It enhancesÂ
conversion of toxic metabolites to nontoxic metabolites.Â
Acetaminophen (N-acetyl-para-aminophenol, paracetamol, APAP)Â
toxicity is common primarily because the medication is so readilyÂ
available, and there is a perception that it is very safe. More than 60Â
million Americans consume acetaminophen on a weekly basis. AllÂ
patients with high levels of acetaminophen need admission andÂ
treatment with N-acetyl-cysteine (NAC). This agent is fully protectiveÂ
against liver toxicity if given within 8 hours after ingestion. o Option A: Deferoxamine mesylate is the antidote for ironÂ
intoxication. Desferal is indicated for the treatment of acute ironÂ
intoxication and chronic iron overload due to transfusiondependent anemias. Desferal is an adjunct to, and not aÂ
substitute for, standard measures used in treating acute ironÂ
intoxication, which may include the following: induction of emesis
with syrup of ipecac; gastric lavage; suction and maintenance ofÂ
a clear airway; control of shock with intravenous fluids, blood, oxygen, and vasopressors; and correction of acidosis. o Option B: Succimer is an antidote for lead poisoning.Â
Succimer is an oral heavy metal chelating agent used to treatÂ
lead and heavy metal poisoning. Succimer has been linked to aÂ
low rate of transient serum aminotransferase elevations duringÂ
therapy, but its use has not been linked to cases of clinicallyÂ
apparent liver injury with jaundice. Succimer does notÂ
significantly chelate essential metals such as zinc, copper, orÂ
iron, and its specificity, safety and oral availability make itÂ
preferable to other chelating agents for treating lead poisoningÂ
such as Ca-EDTA which must be given intravenously andÂ
dimercaprol (British anti-Lewisite [BAL) which requiresÂ
intramuscular administration. o Option C: Flumazenil reverses the sedative effects ofÂ
benzodiazepines. Flumazenil is a benzodiazepine antagonist.Â
Flumazenil is also indicated for the management and treatmentÂ
of benzodiazepine overdose in adults. It is useful in reversingÂ
coma due to benzodiazepine overdose. Flumazenil is moreÂ
effective in reversing sedation or coma in patients withÂ
benzodiazepine intoxication rather than in patients with multipleÂ
drug overdoses.