1. Question
Flumazenil (Romazicon) has been ordered for a male client who has overdosed on oxazepam (Serax). Before administering the medication,ÂÂ
nurse Gina should be prepared for which common adverse effect?
o A. Seizures o B. Shivering
o C. Anxiety o D. Chest pain
Incorrect
Correct Answer: A. Seizures
Seizures are the most common serious adverse effect of usingÂÂ
flumazenil to reverse benzodiazepine overdose. The effect is magnified
if the client has a combined tricyclic antidepressant andÂÂ
benzodiazepine overdose. Benzodiazepine reversal has correlationsÂÂ
with seizures. Seizures may happen more frequently in patients whoÂÂ
have been on benzodiazepines for long-term sedation or in patientsÂÂ
who are showing signs of severe tricyclic antidepressant overdose. The
required dosage of Flumazenil should be measured and prepared byÂÂ
the practitioners to manage seizures. Flumazenil use requires cautionÂÂ
in patients relying on a benzodiazepine for seizure control. o Option B: Shivering is not an adverse effect of flumazenil.ÂÂ
Monitor the patient for the possible return of sedation, mostly inÂÂ
those who are tolerant of benzodiazepines. Patients should haveÂÂ
monitoring for respiratory depression, benzodiazepineÂÂ
withdrawal, and other residual effects of benzodiazepines for atÂÂ
least 2 hours. o Option C: Anxiety is a rare adverse effect for people usingÂÂ
flumazenil. Flumazenil has some associations with precipitation of
seizures in patients with benzodiazepine dependence with aÂÂ
history of seizures. Flumazenil overdose is extremely rare. ThereÂÂ
is no precise antidote for flumazenil toxicity. In mild to severe toxicity, symptomatic and supportive treatment should be aÂÂ
consideration. o Option D: An overdose of flumazenil in a patient who is not
a chronic benzodiazepine user would not be expected. ChronicÂÂ
benzodiazepines users may experience withdrawal with abruptÂÂ
discontinuation of the drug. Administration of benzodiazepines orÂÂ
barbiturates may be necessary for seizure control. ï‚· 2. Question
Nurse Tamara is caring for a client diagnosed with bulimia. The mostÂÂ
appropriate initial goal for a client diagnosed with bulimia is to:
o A. Avoid shopping for large amounts of food. o B. Control eating impulses. o C. Identify anxiety-causing situations. o D. Eat only three meals per day. Incorrect
Correct Answer: C. Identify anxiety-causing situations
Bulimic behavior is generally a maladaptive coping response to stress and underlying issues. The client must identify anxiety-causingÂÂ
situations that stimulate the bulimic behavior and then learn new ways
of coping with the anxiety. Bulimia nervosa is a condition that occursÂÂ
most commonly in adolescent females, characterized by indulgence inÂÂ
binge-eating, and inappropriate compensatory behaviors to preventÂÂ
weight gain. o Option A: Controlling shopping for large amounts of foodÂÂ
isn’t a goal early in treatment. It is important to educate patientsÂÂ
who abuse laxatives that these medications work in theÂÂ
gastrointestinal tract after the areas where caloric absorption has occurred primarily. It is crucial to inform patients that a period ofÂÂ
edema and weight gain may follow up to several weeks afterÂÂ
discontinuation of purging behavior. o Option B: Managing eating impulses and replacing themÂÂ
with adaptive coping mechanisms can be integ into the plan
of care after initially addressing stress and underlying issues. TheÂÂ
primary objective of treatment is a cessation of the binging andÂÂ
purging behavior. Selective serotonin reuptake inhibitors such asÂÂ
fluoxetine, citalopram, and sertraline have shown to reduceÂÂ
symptoms of bulimia nervosa. Fluoxetine is the only FDAÂÂ
approved medication for bulimia nervosa. It appears that a higher
dose (60 mg) is significantly better than a placebo in decreasingÂÂ
the frequency of binge and vomiting episodes. o Option D: Eating three meals per day isn’t a realistic goalÂÂ
early in treatment. Patients with bulimia nervosa who purge byÂÂ
vomiting often brush their teeth immediately after purging, which
can accelerate dental erosion. The clinician should instruct theÂÂ
patients who persist in vomiting to rinse their mouths with waterÂÂ
or fluoride rather than brushing their teeth within 30 minutes ofÂÂ
each episode. Consider consulting a dentist to address dentalÂÂ
issues associated with vomiting. ï‚· 3. Question
A female client who’s at high risk for suicide needs close supervision.ÂÂ
To best ensure the client’s safety, Nurse Mary should:
o A. Check the client frequently at irregularÂÂ
intervals throughout the night. o B. Assure the client that the nurse will hold inÂÂ
confidence anything the client says. o C. Repeatedly discuss previous suicide attempts withÂÂ
the client. o D. Disregard decreased communication by the clientÂÂ
because this is common with suicidal clients.
Incorrect
Correct Answer: A. Check the client frequently at irregularÂÂ
intervals throughout the night
Checking the client frequently but at irregular intervals prevents theÂÂ
client from predicting when observation will take place and alteringÂÂ
behavior in a misleading way at these times. Once the patient isÂÂ
deemed to be at risk for suicide, then intervention steps must beÂÂ
initiated right away. The individual must not be left alone. Enlist theÂÂ
help of a support person while at home. The suicidal individual must be
treated in a safe and secure place. In addition, the place has to beÂÂ
monitored. o Option B: This may encourage the client to try toÂÂ
manipulate the nurse or seek attention for having a secret suicide
plan. Assessing the individual’s judgment is critical. One shouldÂÂ
try and determine how the individual can handle stress. Does heÂÂ
or she have an impairment in decision making? Does theÂÂ
individual know that jumping in front of a train is dangerous?ÂÂ
Reflect empathy and concern. Offer a hand to help. Provide theÂÂ
patient with confidence that he or she can overcome the issues. o Option C: This may reinforce suicidal ideas. Help developÂÂ
internal coping strategies (e.g., exercise, journaling, reading,ÂÂ
developing a hobby). Utilize the help of healthcare professionalsÂÂ
to follow up on therapy. Once the individual is safe as an inpatient
or outpatient, a formal treatment plan should be established. The next step is to refer all patients deemed to be at higher risk for suicide to a mental health counselor as soon as possible. EveryÂÂ
state has laws and procedures regarding this process which mustÂÂ
be incorpo into the clinical practice when addressingÂÂ
individuals at high suicide risk. o Option D: Decreased communication is a sign ofÂÂ
withdrawal that may indicate the client has decided to commitÂÂ
suicide; the nurse shouldn’t disregard it. In some cases,ÂÂ
assessment of the mental status may provide a clue to theÂÂ
individual’s potential for self-harm. Depressed patients will oftenÂÂ
tend to appear unclean and unkempt. The clothing may not beÂÂ
ironed or dirty. The risk of suicide is often high in people whoÂÂ
appear very anxious or depressed. The patient may exhibit a flatÂÂ
affect or no emotions at all. Some depressed patients mayÂÂ
develop hallucinations that may be telling him or her to killÂÂ
themselves. The majority of these hallucinations are auditory. ï‚· 4. Question
Which of the following drugs should Nurse Mary prepare to administerÂÂ
to a client with a toxic acetaminophen (Tylenol) level?
o A. Deferoxamine mesylate (Desferal) o B. Succimer (Chemet) o C. Flumazenil (Romazicon) o D. Acetylcysteine (Mucomyst)
Incorrect
Correct Answer: D. Acetylcysteine (Mucomyst)
The antidote for acetaminophen toxicity is acetylcysteine. It enhancesÂÂ
conversion of toxic metabolites to nontoxic metabolites.ÂÂ
Acetaminophen (N-acetyl-para-aminophenol, paracetamol, APAP)ÂÂ
toxicity is common primarily because the medication is so readilyÂÂ
available, and there is a perception that it is very safe. More than 60ÂÂ
million Americans consume acetaminophen on a weekly basis. AllÂÂ
patients with high levels of acetaminophen need admission andÂÂ
treatment with N-acetyl-cysteine (NAC). This agent is fully protectiveÂÂ
against liver toxicity if given within 8 hours after ingestion. o Option A: Deferoxamine mesylate is the antidote for ironÂÂ
intoxication. Desferal is indicated for the treatment of acute ironÂÂ
intoxication and chronic iron overload due to transfusiondependent anemias. Desferal is an adjunct to, and not aÂÂ
substitute for, standard measures used in treating acute ironÂÂ
intoxication, which may include the following: induction of emesis
with syrup of ipecac; gastric lavage; suction and maintenance ofÂÂ
a clear airway; control of shock with intravenous fluids, blood, oxygen, and vasopressors; and correction of acidosis. o Option B: Succimer is an antidote for lead poisoning.ÂÂ
Succimer is an oral heavy metal chelating agent used to treatÂÂ
lead and heavy metal poisoning. Succimer has been linked to aÂÂ
low rate of transient serum aminotransferase elevations duringÂÂ
therapy, but its use has not been linked to cases of clinicallyÂÂ
apparent liver injury with jaundice. Succimer does notÂÂ
significantly chelate essential metals such as zinc, copper, orÂÂ
iron, and its specificity, safety and oral availability make itÂÂ
preferable to other chelating agents for treating lead poisoningÂÂ
such as Ca-EDTA which must be given intravenously andÂÂ
dimercaprol (British anti-Lewisite [BAL) which requiresÂÂ
intramuscular administration. o Option C: Flumazenil reverses the sedative effects ofÂÂ
benzodiazepines. Flumazenil is a benzodiazepine antagonist.ÂÂ
Flumazenil is also indicated for the management and treatmentÂÂ
of benzodiazepine overdose in adults. It is useful in reversingÂÂ
coma due to benzodiazepine overdose. Flumazenil is moreÂÂ
effective in reversing sedation or coma in patients withÂÂ
benzodiazepine intoxication rather than in patients with multipleÂÂ
drug overdoses.