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1. A client is prescribed phenobarbital sodium (Luminal) for a seizure disorder. The medication has a long half-life of 4 days. Based on this half-life, the medication will most likely be prescribed A. once a day. B. twice a day. C. three times a day. D. four times a day.: Answer: ANS: A Medication with long half-lives remain at their therapeutic levels between doses for long periods of time. Therefore, this medication can be administered once a day. 2. A nurse educator is reviewing medication dosages and factors that influence medication metabolism with a group of nurses. Medication dosages may need to be decreased for which of the following reasons? (Select all that apply.) A. Increased renal excretion B. Increased medication-metabolizing enzymes C. Liver failure D. Peripheral vascular disease E. Concurrent use of medication metabolized by the same pathway: Answer: ANS: C, E Liver failure decreases metabolism and thus increase the concentration of medication. This may require decreasing the dosage of medication. When two medicationsÂ
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