ACRP CCRC EXAM QUESTION WITH COMPLETE SOLUTION

ACRP CCRC EXAM QUESTION WITH COMPLETE SOLUTION
Question : The DSMB has prematurely terminated a trial
evaluating an investigational pain medication that is taken one
caplet orally b.i.d. for chronic hip pain. Subjects are allowed to
take one extra caplet per day. Subjects receive a sufficient
quantity of IP for 14 days plus two additional doses. Which of
the following represents a drug accountability issue?1) Subject
A returns 24 pills after 10 days on trial.2) Subject B returns 12
pills after 8 days on the trial.3) Subject C returns 29 pills after 5
days on the trial.4)Subject D returns 42 pills after 1 day on the
trial.
Correct answer: Subject B returns 12 pills after 8 days on the
trial.
Question : A subject is issued 120 tablets and is instructed to
take 2 tablets 4 times a day. He returns 88 tablets on the
morning of day 9 fasting for laboratory tests. What percent
compliant is he?
Correct answer: 50%
Question : Twenty-six subjects were enrolled in a pneumonia
trial. The site received 100 bottles of IP. Each subject received 

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