ADVANCED PHARMACOLOGY NR 565 MIDTERM CHAMBERLAIN COMPLETE STUDY QUESTIONS WITH VERIFIED ANSWERS (GUARANTEED PASS) | RATED A+

ADVANCED PHARMACOLOGY NR 565 MIDTERM CHAMBERLAIN COMPLETE STUDY QUESTIONS WITH VERIFIED ANSWERS (GUARANTEED PASS) | RATED A+

ADVANCED PHARMACOLOGY NR 565 MIDTERM CHAMBERLAIN
During what trimester is a pregnant woman most at risk for adverse drug reactions with
potential long term consequences? - Answer>>> 1st trimester (fetus most at risk d/t rapid
growth)
What is BEERS criteria? - Answer>>> Recommendations of medications inappropriate for elderly
(65 and older), prescriber ultimately decides
What is the CYP450 (cytochrome P450) - Answer>>> liver enzyme system where medications are
metabolized, can either be inducers or inhibitors and create drug-drug interactions
CYP450 inducers - Answer>>> Speed up metabolism of drugs (drug is cleared faster), drug has
lesser effect (decrease blood levels of drug), elevate CYP450 enzymes
CYP450 inducers pneumonic - Answer>>> "Bullshit Crap GPS INDUCES rage"
CYP450 inducer drug names - Answer>>> Barbituates, St John wort, Carbamazepine, rifampin,
alcohol, phenytoin, griseofulvin, phenobarbital, sulfonylureas
CYP450 inhibitors - Answer>>> inhibit metabolism, increase blood levels of medications
CYP450 pneumonic - Answer>>> "VISA credit card debt INHIBITS spending on designers like CK to
look GQ"
CYP450 inhibitors drug names - Answer>>> Valproate, isoniazid, sulfonamides, amiodarone,
chloramphenicol, ketoconazole, grapefruit juice, quinidine
Physiological changes during pregnancy that impact pharmacodynamics and pharmacokinetic
properties of drugs? - Answer>>> increase glomerular filtration rate leads to increase durg
excretion
increase hepatic metabolism
decrease tone and motility of bowel
increase drug absorption
Examples of medications that can be teratogenic - Answer>>> Antiepileptic drugs, antimicrobials
such as tetracyclines and fluoroquinolones, vitamin A in large doses, some anticoagulants, and
hormonal medications such as diethylstilbestrol (DES).
How is absorption of intramuscular medications different in neonates? - Answer>>> slow and
erratic due to low blood flow in muscles first few days of life
Why is absorption of medication in the stomach increased in infancy? - Answer>>> delayed
gastric emptying