AGNP BOARD EXAM QUESTIONS Respiratory

AGNP BOARD EXAM QUESTIONS Respiratory Prescribing (Questions 100)

Question:

Treatment of Bordetella pertussis in a patient with a hypersensitivity to

macrolides is: doxycycline.

clindamycin (Cleocin).metronidazole (Flagyl).sulfamethoxazole/trimethoprim (Bactrim). Correct

Explanation:

Sulfamethoxazole/trimethoprim (Bactrim) is an alternative choice for patients in whom a macrolide is contraindicated.

Question:

The mainstay of treatment in the management of mild and moderate croup is

symptomatic relief that includes:

antibiotics.beta-2 agonists.corticosteroids.Correct decongestants.

Explanation:

The mainstay of treatment in the management of mild and moderate croup is symptomatic relief, which includes corticosteroids (inhaled or oral). Antibiotics, beta-2 agonists and decongestants have not been studied, and their use is discouraged.

Question:

In adults with community-acquired pneumonia in which B-lactamase producing Haemophilus influenzae is identified as the causative

organism, the outpatient treatment of choice is:

amoxicillin (Amoxil).azithromycin (Zithromax). Cefixime (Suprax). Correct oseltamivir (Tamiflu).

Explanation:

The treatment of choice in adults with B-lactamase producing Haemophilus influenzae community acquired pneumonia is cefixime (Suprax). Amoxicillin is recommended in the presence of non-B-lactamase producing Haemophilus influenzae. Alternate antibiotics include fluoroquinolones (ie. moxifloxacin [Avelox]), doxycycline, azithromycin and clarithromycin.

Question:

A patient with sinusitis is treated with amoxicillin. Caution is advised with

concomitant use of:

lisinopril (Zestril).fexofenadine (Allegra).

warfarin (Coumadin). Correct furosemide (Lasix).

Explanation:

Amoxicillin should be used with caution with warfarin (Coumadin). The combination will increase the INR and thus increase the risk of bleeding, possibly due to altered vitamin K production by gut flora. Amoxicillin can be co- administered with lisinopril (Zestril), fexofenadine (Allegra), and furosemide (Lasix).

Question:

A patient with bacterial sinusitis taking an oral penicillin should be

instructed: to monitor capillary blood glucose readings if they have

diabetes.that additional protection against pregnancy is necessary if they are taking an oral contraceptive. Correct to use an anti-diarrheal if they experience diarrhea.to avoid penicillin if they are pregnant or trying to become pregnant.

Explanation:

Penicillin is a beta-lactam antibiotic. The drug interactions of most concern with the beta-lactam antibiotics are those with oral contraceptive products, methotrexate and valproic acid. In the case oral contraceptives, even though a small percentage of women may potentially experience decreased effectiveness of these birth control products while taking beta-lactam antibiotic, alternative birth control methods should be considered while taking these antibiotics. Anti-diarrheal medicine should not be taken because it may worsen or prolong diarrhea. Most penicillins are safe to use during pregnancy. Penicillins may cause false readings with some urine glucose tests.

Question:

An example of a beta2-adrenergic receptor agonist used in the treatment of

asthma is: dobutamine.

denopamine.xamoterol.albuterol. Correct

Explanation:

ß2 (beta2) adrenergic receptor agonists, also known as adrenergic ß2 receptor agonists, act on the ß2 adrenergic receptor. Like other ß adrenergic agonists, they cause smooth muscle relaxation. ß2 adrenergic agonists' effects on smooth muscle cause dilation of bronchial passages. They are primarily used to treat asthma and other pulmonary disorders, such as COPD. Examples of a beta2-adrenergic receptor agonists are albuterol, xamoterol, and terbutaline.The others are examples of beta1-adrenergic receptor agonists.

Question:

Benzonatate (Tessalon Perles), a non-narcotic

antitussive,: does not cause sedation.

is centrally acting on cough receptors. is safe in children 6 years and older. should be swallowed whole. Correct

Explanation:

Benzonatate (Tessalon Perles) capsules act peripherally by anesthetizing the stretch receptors located in the respiratory passages, lungs, and pleura by dampening their activity and thereby reducing the cough reflex. It is approved for the relief of cough in adults and children older than 10 years. Benzonatate capsules should be swallowed whole. Severe hypersensitivity reactions (including bronchospasm, laryngospasm and cardiovascular collapse) have been reported from sucking or chewing the capsule instead of swallowing it.This is thought to be related to a local anesthetic property of the drug. The most common side effects of benzonatate are sedation, headache and dizziness.

Question:

Which of the following medications, when combined with pulmonary rehabilitation, enhances exercise performance?Ipratropium bromide (Atrovent). Levalbuterol (Xopenex) inhaled.Salmeterol (Serevent Diskus).Tiotropium (Spiriva HandiHaler). Correct

Explanation:

Tiotropium (Spiriva HandiHaler), a long-acting antimuscarinic antagonist, enhances the effectiveness of pulmonary rehabilitation in increasing exercise performance.

Question:

Which of the following would NOT be a potential adverse reaction of an intramuscular corticosteroid?anuria. Correct angioedema.cardiac arrhythmias.mood swings.

Explanation:

Anuria has not been reported as a potential side effect of intramuscular corticosteroids. Reactions that may occur include anaphylaxis, angioedema, convulsions, depression, emotional instability, euphoria, headache, insomnia, mood swings, neuritis, neuropathy, paresthesia, personality changes, bradycardia, cardiac arrest, cardiac arrhythmias, cardiac enlargement, circulatory collapse, congestive heart failure, and tachycardia.

Question:

Doxycycline (Vibramycin), for the treatment of pneumonia, is classified as a:

fluoroquinolone.penicillin.macrolide.tetracycline.Correct

Explanation: