A-level BIOLOGY 7402/3 Paper 3 Mark scheme June 2026
Question Marking Guidance Mark Comments
01.1
1. (There are) stretch-mediated sodium ionÂÂ
channels (in the membrane);
2. (Increased pressure) deforms/changesÂÂ
(sensory neurone/axon) membrane/lamella(e)
OR
(Increased pressure) deforms/changes sodiumÂÂ
ion channels;
3. Sodium ion channels open;
4. Sodium ions diffuse in;ÂÂ
5. Depolarisation (leading to generator potential);
3 max
(3 xÂÂ
AO1)
1. 2. 3. or 4. AcceptÂÂ
N
Max 2 if onlyÂÂ
reference to sodiumÂÂ
and not sodium ions
4. Accept sodiumÂÂ
ions move in downÂÂ
a concentrationÂÂ
gradient
5. Accept insideÂÂ
becomes positive