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Which of the following cellular hallmarks of cancer is characterized by
uncontrolled cell growth and division?
 a) Angiogenesis
 b) Sustained proliferative signaling
 c) Evasion of growth suppressors
 d) Tumor-promoting inflammation
 Answer: b) Sustained proliferative signaling
 Rationale: Sustained proliferative signaling refers to the ability of cancer
cells to continuously receive signals for cell growth and division, leading
to uncontrolled proliferation.
What is the process by which cancer cells stimulate the formation of new
blood vessels to supply nutrients and oxygen to the tumor?
 a) Angiogenesis
 b) Resisting cell death
 c) Deregulating cellular energetics
 d) Enabling replicative immortality
 Answer: a) Angiogenesis
 Rationale: Angiogenesis is a hallmark of cancer that allows tumors to
induce the formation of new blood vessels, supporting their growth and
metastasis.
Which hallmark of cancer involves the ability of cancer cells to evade
programmed cell death?
 a) Tumor-promoting inflammation
 b) Evading immune destruction
 c) Resisting cell death
 d) Activating invasion and metastasis
 Answer: c) Resisting cell death
 Rationale: Cancer cells can resist programmed cell death (apoptosis),
allowing them to survive and proliferate uncontrollably.
The process of altering cellular metabolism to support the energy
requirements of cancer cells is known as:
 a) Evading growth suppressors
 b) Deregulating cellular energetics
 c) Enabling replicative immortality
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