CNS DISORDER FINAL EXAM QNS & ANS 2026/2027 7pages

1. The dopamine hypothesis initially stated that in people with schizophrenia, certain regions of the brain contain excess dopamine, thereby causing symptoms of the disease, particularly positive symptoms. a. True b. False c. Not stated d. Unknown 2. The dopamine hypothesis arose and has since been supported by, several observations. These are the following except: a. Most antipsychotic drugs that are effective in treating the positive symptoms of schizophrenia block dopamine D2 receptors. b. Drugs that increase dopamine levels in the brain, including amphetamines and cocaine, mimic the positive symptoms of schizophrenia. c. A higher density of D2 receptors has been found postmortem in the frontal cortex of people with schizophrenia. d. None of the Above 3. The positive symptoms of schizophrenia, such as delusions and hallucinations, are thought to result from excess activity in the . a. Mesocortical Dopaminergic Pathways b. Mesolimbic Dopaminergic Pathways c. Nigrostriatal Pathway d. Tuberoinfundibular Pathways 4. Deficits in are believed to be involved in the development of negative symptoms (e.g. alogia, and anhedonia) and some cognitive deficits associated with schizophrenia. a. Mesocortical Concentrations b. Mesolimbic Dopaminergic Pathways c. Nigrostriatal Pathway d. Tuberoinfundibular Pathways 5. Normal dopamine function in this pathway helps control movements, while deficiencies may cause movement disorders. a. Mesocortical Concentrations b. Mesolimbic Dopaminergic Pathways c. Nigrostriatal Pathway d. Tuberoinfundibular Pathways 6. It is a profound inner restlessness and a compulsion to move accompanied by restless motion a. Dystonia b. Akathisia c. Akinesia d. None of the Above