(FNP) D116 NURS 6800 Advanced Pharmacology LATEST OA EXAM QUESTIONS & ANSWERS
1. Question: Which cytochrome P450 enzyme is primarily
responsible for the metabolism of warfarin?
- A) CYP1A2
- B) CYP2C9
- C) CYP3A4
- D) CYP2D6
Answer: B) CYP2C9
Rationale: Warfarin is primarily metabolized by CYP2C9, and
variations in this enzyme can significantly affect drug levels and
patient response.
2. Question: Which of the following antihypertensive
medications is contraindicated in pregnancy due to teratogenic
effects?
- A) Labetalol
- B) Methyldopa
- C) Losartan
- D) Nifedipine
Answer: C) Losartan
Rationale: Losartan is an angiotensin receptor blocker (ARB),
which is contraindicated in pregnancy, particularly in the second
and third trimesters, due to the risk of fetal harm.
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